Chaoxin Man
Northeast Agricultural University
FermentationGeneColloidal goldDetection limitAptamerChemistryCronobacter sakazakiiLactobacillus rhamnosusLactobacillus plantarumLactobacillus paracaseiCronobacterProbioticFood scienceChromatographyBacteriaEscherichia coliBiochemistryLoop-mediated isothermal amplificationMultilocus sequence typingBiologyMicrobiology
29Publications
8H-index
176Citations
Publications 35
Newest
#1Lihan Wang (NEAU: Northeast Agricultural University)H-Index: 2
#2Xinyi Pang (Nanjing University of Finance and Economics)
Last. Chaoxin Man (NEAU: Northeast Agricultural University)H-Index: 8
view all 11 authors...
Abstract null null Cronobacter sakazakii (C. sakazakii) is a food-borne pathogen that can be spread by powdered infant formula (PIF) to cause illness in infants. Bacteriophages (phages) are an effective potential strategy to control food-borne pathogens. Phage JK004 which isolated from the native environment of C. sakazakii was a novel virulent phage with short latent period and large burst size. JK004 had tolerance to heat, pH and osmotic-stress. The phage JK004 did not contain known virulence,...
Source
#1Lihan Wang (NEAU: Northeast Agricultural University)H-Index: 2
#2Jiaxin Zhang (NEAU: Northeast Agricultural University)
Last. Yujun Jiang (NEAU: Northeast Agricultural University)H-Index: 8
view all 9 authors...
Symbiotic gut microbiota in early life plays a vital role in human health, and changes in its communication and function are associated with various complex disorders. In this study, we analyzed the gut flora communication of 6 infants at 4 months of age and determined the disturbances related to antibiotic treatment. By the culturomics and Single Molecule Real-time sequencing methods, a total of 6234 strains were divided into 16 genera and 45 species. The alpha diversity of culturable microorga...
Source
#2Jiapeng ZhengH-Index: 1
view all 7 authors...
Probiotics can prevent obesity and related metabolic complications. In our study, the protective effect and molecular mechanism of Lactobacillus rhamnosus JL1 (separated from the feces of healthy infants) on high-fat diet mice were investigated. After 10 weeks of dietary intervention with L. rhamnosus JL1 intervention, the body weight of the JL1 group (23.78 g) was significantly lower than that of the HFD group (26.59 g, p < 0.05) and the liver index was reduced. Serum biochemical analysis showe...
Source
#1Sihan ChenH-Index: 5
Last. Yujun JiangH-Index: 8
view all 8 authors...
Salmonella typhimurium (S. typhimurium) is a foodborne pathogen that has caused numerous outbreaks worldwide, necessitating the development of on-site strategy to prevent early contamination. Here, we set up an enzyme-free strategy for aptamer-catalyzed hairpin assembly in which salt-induced aggregation of unmodified gold nanoparticles (AuNPs) served as a colorimetric signal output, allowing on-site detection of S. typhimurium in milk. The aptamer-functionalized magnetic beads were used as a veh...
Source
#1Xinyan Yang (NEAU: Northeast Agricultural University)H-Index: 5
#2Lihan Wang (NEAU: Northeast Agricultural University)H-Index: 2
Last. Yujun Jiang (NEAU: Northeast Agricultural University)H-Index: 8
view all 8 authors...
Abstract null null A novel fluorescent platform of DNA-stabilized silver nanoclusters (DNA-AgNCs) has been developed based on exonuclease III (Exo III) amplification-assisted for simple and sensitive detection of Salmonella Typhimurium (S. Typhimurium). The platform was designed by using magnetic beads, aptamer, its complementary DNA, hairpin probe (HP), Exo III, AgNO3, and NaBH4. The functionalized HP contained a cytosine-rich oligonucleotide loop (C-rich loop), which served as an effective tem...
Source
#1Xue Qin (NEAU: Northeast Agricultural University)H-Index: 3
#2Hao Wang (NEAU: Northeast Agricultural University)H-Index: 4
Last. Yujun Jiang (NEAU: Northeast Agricultural University)H-Index: 8
view all 9 authors...
Abstract null null The genus Cronobacter is an opportunistic food-borne pathogen which is able to adapt to diverse environments and shows considerable genetic diversity. Genomic analysis can be used to reveal the variation across the genus with respect to virulence, drug resistance and factors involved in horizontal gene transfer mechanisms, such as integrons, conjugative plasmids, and recombinases. In this study, whole-genome comparative analysis of 27 Cronobacter genomes (12 existing and 15 ne...
Source
#1Lihan Wang (NEAU: Northeast Agricultural University)H-Index: 2
#2Stephen Forsythe (University of Nottingham)H-Index: 6
Last. Yujun Jiang (NEAU: Northeast Agricultural University)H-Index: 8
view all 6 authors...
ABSTRACT null null Members of the Cronobacter genus include food-borne pathogens that can cause infections in infants, with a mortality rate as high as 40 to 80%. The high fatality rate of Cronobacter and its isolation from numerous types of food, especially from powdered infant formula, demonstrate the serious nature of this organism. The source tracking of Cronobacter spp. and the analysis of high-frequency species from different sources are helpful for a more targeted control. Furthermore, th...
Source
#1Yuwei Ren (NEAU: Northeast Agricultural University)H-Index: 1
#2Pingping Gao (NEAU: Northeast Agricultural University)H-Index: 1
Last. Yujun Jiang (NEAU: Northeast Agricultural University)H-Index: 8
view all 11 authors...
ABSTRACT Escherichia coli O157:H7 (E. coli O157:H7), one of the most widespread foodborne pathogens, can cause a series of diseases and even lead to death. In this study, a highly sensitive method was developed by combining aptamer-exonuclease III (Exo III)–assisted amplification with lateral flow assay (LFA) based on gold nanoparticles (AuNP). The compound of single-stranded (ss) DNA-anti-E. coli O157:H7 aptamer (ssDNA-aptamer) was formed by hybridization between designed target ssDNA and aptam...
Source
#1Tao Yang (NEAU: Northeast Agricultural University)H-Index: 3
#2Zhenghui Wang (NEAU: Northeast Agricultural University)H-Index: 2
Last. Yujun Jiang (NEAU: Northeast Agricultural University)H-Index: 8
view all 10 authors...
Effective testing tools for Escherichia coli O157:H7 can prevent outbreaks of foodborne illness. In this paper, a smartphone-based colorimetric aptasensor was developed using functionalized gold nanoparticles (GNP) and multi-walled carbon nanotubes (MWCNT) for monitoring E. coli O157:H7 in milk. The maximum absorption peak of GNP bonded with aptamer (Apt) generated evident transformation from 518 to 524 nm. The excess GNP-Apt was removed by functionalized MWCNT magnetized with carbonyl iron powd...
Source
#1Pingping GaoH-Index: 1
#2Lihan WangH-Index: 2
Last. Yujun JiangH-Index: 8
view all 10 authors...
In this paper, a novel and ultrasensitive lateral flow assay (LFA) based on aptamer–magnetic separation, and multifold Au nanoparticles (AuNPs) was developed for visual detecting Salmonella enterica ser. Typhimurium (S. Typhimurium). The method realized magnetic enrichment and signal transduction via magnetic separation and achieved signal amplification through hybridizing AuNPs–capture probes and AuNPs–amplification probes to form multifold AuNPs. Two different thiolated single-strand DNA (ssDN...
Source
This website uses cookies.
We use cookies to improve your online experience. By continuing to use our website we assume you agree to the placement of these cookies.
To learn more, you can find in our Privacy Policy.