Hsin‐An A. Chen
Taipei Medical University
Proinflammatory cytokineKidney diseaseKidneyIcariinEpimediumRenal fibrosisTubulointerstitial fibrosisMedicineInterleukinPharmacology
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#1Hsin‐An A. Chen (TMU: Taipei Medical University)H-Index: 1
#2Chang-Mu Chen (NTU: National Taiwan University)H-Index: 11
Last. Shing-Hwa Liu (NTU: National Taiwan University)H-Index: 44
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Abstract Background The pathology change of renal tubulointerstitial fibrosis is a critical feature of chronic kidney disease (CKD), regardless of the primary insults. The infiltration of inflammatory cells and the consecutive secretion of profibrotic factors are frequently and conspicuously observed during the development of renal fibrosis. Icariin, an active polyphenol of the Epimedium genus, has been found to alleviate the symptoms of chronic diseases like diabetes, neurodegeneration, and hea...
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