Jianhong An
Guangzhou Higher Education Mega Center
Survival analysisGermline mutationVimentinBasal (phylogenetics)Lung cancerHyperplasiaLungProstate cancerWound healingAdenocarcinomaCell morphologyGene mutationCancer researchProportional hazards modelCell growthMedicineMissense mutationBiologyCancer cell
Publications 3
#1Jianhong AnH-Index: 1
Last. Hong Shen (Guangzhou Higher Education Mega Center)
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#2Chunya ChenH-Index: 1
Last. Hong Shen (Guangzhou Higher Education Mega Center)
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Aim Basal epithelial cells are absent in distant prostate cancer. This study aimed to investigate whether basal epithelial cells could suppress migration and invasion of prostate cancer cells to become a new treatment strategy for prostate cancer. Main methods Basal epithelial cells were identified by immunofluorescence with anti-p63. Wound healing assays or transwell assays were used to explore the effects of basal epithelial cells, TGF-β1, SB431542 (inhibitor of TGF-β type I receptor) or statt...
#1Xingyu Cheng (Guangzhou Higher Education Mega Center)H-Index: 1
#2Han Yin (Guangzhou Higher Education Mega Center)H-Index: 1
Last. Hong Shen (Southern Medical University)H-Index: 1
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Purpose Lung cancer prevalence with its high mortality rate is a trending topic globally. Non-small cell lung cancer (NSCLC) is the most common type of lung cancer. The human gene TTN encoding for TITIN protein is known as major mutation gene in many types of tumor including NSCLC. However, it is still controversial that TTN is a cancer-associated candidate considering tumor heterogeneity and complex genetic structure. In-depth researches on correlation between TTN mutation and NSCLC are still l...
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