Ilaria Silvestro
Sapienza University of Rome
FoulingNuclear chemistryNanoparticleChemistryMaterials scienceBioremediationGraftingPolyethylene glycolBiocompatibilityHyaluronic acidGlutaraldehydeStaphylococcus epidermidisSwellingPolyurethaneChitosanOxideWound healingTrametes versicolorMechanical strengthChitosan scaffoldWound careGraphenePhoto crosslinkingCompressive strengthFood scienceImmobilized enzymeChemical engineeringPhase (matter)Tissue engineeringChromiumPolymerPEG ratioBiofilmThermal stabilityBiofoulingPorosityLaccaseFreeze-dryingAdhesionMagnetic nanoparticlesScaffoldWastewater
7Publications
5H-index
56Citations
Publications 7
Newest
#1Ilaria Silvestro (Sapienza University of Rome)H-Index: 5
#2Riccardo Sergi (Sapienza University of Rome)
Last. Iolanda Francolini (Sapienza University of Rome)H-Index: 24
view all 7 authors...
Abstract In this study, a new scaffold fabrication method based on the combination of a series of stabilization processes was set up to obtain chitosan scaffolds with improved mechanical properties for regeneration of load-bearing tissues. Specifically, thermally induced phase separation (TIPS) of chitosan solutions was used to obtain an open structure which was then stabilized by freeze-gelation and photo cross-linking. Freeze-gelation combined with freeze-drying permitted to obtain a porous st...
Source
#1Azzurra Apriceno (Sapienza University of Rome)H-Index: 6
#2Ilaria Silvestro (Sapienza University of Rome)H-Index: 5
Last. Antonella Piozzi (Sapienza University of Rome)H-Index: 23
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Bioremediation with immobilized enzymes has several advantages, such as the enhancement of selectivity, activity, and stability of biocatalysts, as well as enzyme reusability. Laccase has proven to be a good candidate for the removal of a wide range of contaminants. In this study, naked or modified MnFe2O4 magnetic nanoparticles (MNPs) were used as supports for the immobilization of laccase from Trametes versicolor. To increase enzyme loading and stability, MNPs were coated with chitosan both af...
1 CitationsSource
#1Ilaria Silvestro (Sapienza University of Rome)H-Index: 5
#2Iolanda Francolini (Sapienza University of Rome)H-Index: 24
Last. Antonella Piozzi (Sapienza University of Rome)H-Index: 23
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Scaffolds are three-dimensional porous structures that must have specific requirements to be applied in tissue engineering. Therefore, the study of factors affecting scaffold performance is of great importance. In this work, the optimal conditions for cross-linking preformed chitosan (CS) scaffolds by the tripolyphosphate polyanion (TPP) were investigated. The effect on scaffold physico-chemical properties of different concentrations of chitosan (1 and 2% w/v) and tripolyphosphate (1 and 2% w/v)...
6 CitationsSource
#1Ilaria Silvestro (Sapienza University of Rome)H-Index: 5
#2Mariangela Lopreiato (Sapienza University of Rome)H-Index: 4
Last. Iolanda Francolini (Sapienza University of Rome)H-Index: 24
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Wound healing is a dynamic process that can be seriously delayed by many factors including infectious complications. The development of dressings with intrinsic wound healing activity and/or releasing bioactive compounds may help with addressing such an issue. In this study, hyaluronic acid (HA) at different percentages (1–35%) was used to modify chitosan (CS) biological and physico-chemical properties in order to obtain 2D-matrices able to promote healing and protect from infection. HA incorpor...
5 CitationsSource
#1Loris PietrelliH-Index: 18
#2Iolanda FrancoliniH-Index: 24
Last. Marco VoccianteH-Index: 16
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13 CitationsSource
#1Iolanda Francolini (Sapienza University of Rome)H-Index: 24
#2Elena Perugini (Sapienza University of Rome)H-Index: 1
Last. Antonella Piozzi (Sapienza University of Rome)H-Index: 23
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Tissue engineering is a highly interdisciplinary field of medicine aiming at regenerating damaged tissues by combining cells with porous scaffolds materials. Scaffolds are templates for tissue regeneration and should ensure suitable cell adhesion and mechanical stability throughout the application period. Chitosan (CS) is a biocompatible polymer highly investigated for scaffold preparation but suffers from poor mechanical strength. In this study, graphene oxide (GO) was conjugated to chitosan at...
9 CitationsSource
#1Iolanda Francolini (Sapienza University of Rome)H-Index: 24
#2Ilaria Silvestro (Sapienza University of Rome)H-Index: 5
Last. Antonella Piozzi (Sapienza University of Rome)H-Index: 23
view all 5 authors...
Despite advances in material sciences and clinical procedures for surgical hygiene, medical device implantation still exposes patients to the risk of developing local or systemic infections. The development of efficacious antimicrobial/antifouling materials may help with addressing such an issue. In this framework, polyethylene glycol (PEG)-grafted segmented polyurethanes were synthesized, physico-chemically characterized, and evaluated with respect to their bacterial fouling-resistance properti...
15 CitationsSource