Lap Thi Nguyen
Hanoi University
PathophysiologyTransgeneDrug resistanceFear conditioningTumor microenvironmentAmyloid betaAntagonistMetastasisTacrineDrug deliveryAngiogenesisCancer immunotherapyPlatelet-derived growth factorAmyloid precursor proteinMuscarinic acetylcholine receptorCancer researchCarcinogenesisPlateletCancer cellPharmacology
Publications 3
#1Lap Thi Nguyen (Hanoi University)H-Index: 2
#2Nguyen Huu Son (Hanoi University)
Last. Pham Thi Nguyet HangH-Index: 1
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Alzheimer's disease (AD) is a common chronic neurodegenerative disease with well-defined pathophysiological mechanisms. Ilex kudingcha (IK) C.J. Tseng is commonly known as bitter tea or “Khom” tea in Vietnam. The present study was conducted to investigate the anti-dementia effect of IK using olfactory bulbectomized (OBX) mice. OBX mice were daily treated with IK extract (540 mg/kg) or reference drug, tacrine (2.5 mg/kg) 1 week before and continuously for 3 days after the OBX surgery. The object ...
#1Marco Pirisinu (NUS: National University of Singapore)H-Index: 2
#2Tin Chanh Pham (NUS: National University of Singapore)H-Index: 2
Last. Minh T. N. Le (CityU: City University of Hong Kong)H-Index: 15
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Abstract As cancer poses a significant threat to the well-being of humans on a global scale, many researchers have embarked on the search for effective anticancer therapeutic agents. In recent years, many drugs have been shown to have extraordinary anticancer effects. However, in a lot of cases the treatment is accompanied by undesirable side effects due to some intrinsic properties linked to the therapeutic agents, such as poor targeting selectivity and short half-life in the circulation. In th...
7 CitationsSource
#1Phung Thanh Huong (Hanoi University)H-Index: 3
#2Lap Thi Nguyen (Hanoi University)H-Index: 2
Last. Duc-Hiep Bach (SNU: Seoul National University)H-Index: 13
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Besides the critical functions in hemostasis, thrombosis and the wounding process, platelets have been increasingly identified as active players in various processes in tumorigenesis, including angiogenesis and metastasis. Once activated, platelets can release bioactive contents such as lipids, microRNAs, and growth factors into the bloodstream, subsequently enhancing the platelet–cancer interaction and stimulating cancer metastasis and angiogenesis. The mechanisms of treatment failure of chemot...
41 CitationsSource