Sébastien Deferm
University of Hasselt
Subclinical infectionInterquartile rangeInternal medicineUrologyReview articleCardiologyRetrospective cohort studyNatriuresisHemodynamicsProspective cohort studyDeformation (meteorology)Volume overloadSinus rhythmCardiac resynchronization therapyHeart failure with preserved ejection fractionCardioversionMitral annulusAsymptomaticFurosemideHeart failurePressure overloadSpeckle tracking echocardiographyUrine collection deviceDecompensationCulpritDiseaseAtrial fibrillationVentricular remodelingDiureticElectrocardiographyContext (language use)Heart diseaseMitral valve annuloplastyLoop diureticPopulationElectric CardioversionFunctional mitral regurgitationLeft atrialAnalysis softwareMitral regurgitationVentricular functionAdverse outcomesAtrioventricular valveTime to recurrenceCardiovascular mortalityIn patientPatient characteristicsInvasive hemodynamicsUrine outputFunctional mrSt elevation myocardial infarctionPopulation screeningCryptogenic strokeAmbulatoryTroponinMyocardial infarctionStrokeOccultMechanicsMedicineCohortEjection fractionStroke volumeMechanism (biology)
Publications 12
#1H Gruwez (University of Hasselt)H-Index: 1
#2Tine ProesmansH-Index: 2
Last. Laurent PisonH-Index: 28
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Atrial fibrillation (AF) is associated with adverse outcomes. Screening may lead to earlier recognition and treatment of asymptomatic AF. However, most evidence regarding AF applies to clinical AF, with symptoms or electrocardiographic diagnosis. Whether this evidence can be translated toward subclinical AF, without symptoms and detected by novel, more continuous screening devices is uncertain. The diagnostic yield of screening is determined by the screening population, tool, duration and freque...
#1Sébastien DefermH-Index: 4
#2Philippe BertrandH-Index: 39
Last. Steffen Rex (Katholieke Universiteit Leuven)H-Index: 37
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Objectives null Atrial secondary mitral regurgitation (ASMR) is a clinically distinct form of Carpentier type I mitral regurgitation (MR), rooted in excessive atrial and mitral annular dilation in the absence of left ventricular dysfunction. Mitral valve annuloplasty (MVA) is expected to provide a more durable solution for ASMR than for ventricular secondary MR (VSMR). Yet data on MR recurrence and outcome after MVA for ASMR are scarce. This study sought to investigate surgical outcomes and repa...
BACKGROUND Contemporary data on left ventricular function (LVF) recovery in patients with left ventricular dysfunction after ST-elevation myocardial infarction (STEMI) are scarce and to date, no comparison has been made with patients with a baseline normal LVF. This study examined predictors of LVF recovery and its relation to outcomes in STEMI. METHODS Patients presenting with STEMI between January 2010 and December 2016 were categorized in three groups after 3 months according to left ventricu...
#1Sébastien Deferm (University of Hasselt)H-Index: 4
#2Philippe Bertrand (University of Hasselt)H-Index: 39
Last. James D. Thomas (NU: Northwestern University)H-Index: 137
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Abstract null null Objectives null This study aimed to investigate mitral annular dynamics in atrial fibrillation (AF) and after sinus rhythm restoration, and to assess the relationship between annular dynamics and mitral regurgitation (MR). null null null Background null AF can be associated with MR that improves after sinus rhythm restoration. Mechanisms underlying this atrial functional MR (AFMR) are ill-understood and generally attributed to left atrial remodeling. null null null Methods nul...
AIMS To study the loop diuretic (LD) response and effect of LD omission in ambulatory heart failure (HF) patients on chronic low dose LD. METHODS AND RESULTS Urine collections were performed on 2 consecutive days in 40 ambulatory HF patients with 40-80 mg furosemide (day 1 with LD; day 2 without LD). Three phases were collected each day: (1) first 6 hours; (2) rest of the day; and (3) night. On the day of LD intake, the total natriuresis was 129.9 (86.9-155.0) mmol/24h and urine output was 1650 ...
#1Sébastien Deferm (University of Hasselt)H-Index: 4
#2Philippe Bertrand (Harvard University)H-Index: 39
Last. Danita M. Yoerger Sanborn (Harvard University)H-Index: 6
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Background Occult atrial fibrillation (AF) is an important contributor to cryptogenic stroke, yet remains difficult to unmask at presentation. This study investigated the predictive value of left atrial (LA) mechanics by strain echocardiography during stroke hospitalization for the presence of AF as detected on early 30-day monitoring and routine clinical follow-up. Methods Left atrial mechanics were studied by strain echocardiography in a retrospective cohort of 191 patients with cryptogenic st...
Functional or secondary regurgitation of the atrioventricular valves most commonly presents as a consequence of ventricular heart disease. However, there is increasing recognition that functional mitral and/or tricuspid regurgitation can also relate to isolated atrial pathology in the absence of ventricular disease, as seen in atrial fibrillation (AF) and/or heart failure with preserved ejection fraction (HFpEF). The aim of this review article is to summarize recent data and insights into the me...
Abstract Objectives The aim of this study was to assess the effect of congestion and decongestive therapy on left atrial (LA) mechanics and to determine the relationship between LA improvement after decongestive therapy and clinical outcome in immediate or chronic heart failure with reduced ejection fraction (HFrEF). Background LA mechanics are affected by volume/pressure overload in decompensated HFrEF. Methods A total of 31 patients with HFrEF and immediate heart failure (age 64 ± 15 years, 74...
#1Pieter Martens (University of Hasselt)H-Index: 17
#2Sébastien Deferm (University of Hasselt)H-Index: 4
Last. Wilfried MullensH-Index: 38
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Abstract Objectives This study assessed the impact of right-atrial (RA) pacing on left-atrial (LA) physiology and clinical outcome. Background Data for the effects of RA pacing on LA synchronicity, function, and structure after cardiac resynchronization therapy (CRT) are scarce. Methods The effect of RA pacing on LA function, morphology, and synchronicity was assessed in a prospective imaging cohort of heart failure (HF) patients in sinus rhythm with a guideline-based indication for CRT. Additio...
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