Huiyuan Gao
Shenyang Pharmaceutical University
AnalytePharmacokineticsMass spectrometryProinflammatory cytokineChemistryIn vivoCalibration curveArthritisFormic acidCytokineLipopolysaccharideAnti-inflammatoryDexamethasoneOrbitrapTripterygiumChromatographyADMEAbsorption (pharmacology)Pharmacology
Publications 2
#1Miao Wang (SPU: Shenyang Pharmaceutical University)H-Index: 9
#2Da Wang (SPU: Shenyang Pharmaceutical University)H-Index: 4
Last. Zhaohua WuH-Index: 2
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: Cassane diterpenoids (CA) are considered as the main active constituents of medicinal plants belonging to the Caesalpinia genus. Three cassane derivatives, bonducellpin G (BG), 7-O-acetyl-bonducellpin C (7-O-AC) and caesalmin E (CE), isolated from Caesalpinia minax Hance seeds, showed strong anti-inflammatory activity. In this paper, pharmacokinetics (BG, 7-O-AC, CE) and tissue distribution (7-O-AC, CE) properties were studied for the first time using a reliable, sensitive and rapid UHPLC-Q-Or...
1 CitationsSource
#1Ziwei Tong (SPU: Shenyang Pharmaceutical University)H-Index: 1
#2Li Cheng (SPU: Shenyang Pharmaceutical University)H-Index: 2
Last. Zhaohua WuH-Index: 2
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Abstract Ethnopharmacological relevance Seeds of Caesalpinia minax Hance called ‘Ku-Shi-Lian’ (KSL) in China have been used as Zhuang or Dai folk medicines for treatment of common cold, fever, rheumatoid arthritis and dysentery for hundred years. Aim of the study This study aimed to investigate therapeutic efficacy of KSL extract using complete Freund's adjuvant (CFA) induced arthritis in a rat model and the anti-inflammatory activity of cassane diterpenes as the main active material basis of th...
18 CitationsSource