Bei Du
Tianjin Medical University
Fourier transformProteomeMean differenceSubclinical infectionDistortionTransforming growth factorOphthalmologyOptometryEquivalentOmicsRandomized controlled trialEmmetropiaScheimpflug principleChemistryPediatricsProspective cohort studyKeratometerRefractionYoung adultMetabolomicsDioptreAtropineMeasure (physics)Oxidative stressMuscarinic antagonistCorneaDry eyesInflammationMeibomian glandCycloplegiaMetaboliteEye dropGuinea pigAutorefractorKeratoconusFold changeAstigmatismPeptideOrthokeratologyLens (anatomy)Lens placodeCyclopentolateDropout (communications)TropicamideRetinalIntraocular pressureSubjective refractionRefractive errorBone morphogenetic protein 4Human eyeCyclopentolate HydrochlorideEye disorderCycloplegic refractionsAmplitude ratioStatistical analysisContact lensAxial lengthDouble passYoung populationSwath msIn patientTime courseHealthy populationLimits of agreementMixed effectsSpherical equivalentSchool age childAge distributionBone morphogenetic proteinProteomicsReactive oxygen speciesLinear regressionLipidomicsReceiver operating characteristicBioinformaticsTerm (time)Bayesian multivariate linear regressionMedicineArea under the curveActivating transcription factorBiologyMechanism (biology)Cell biologyPharmacologyAnalysis of variance
11Publications
1H-index
6Citations
Publications 12
Newest
Background null To evaluate the necessity of cycloplegia for epidemiological studies of refraction in Chinese young adults (aged 17-22 years) with dark irises, and to compare the cycloplegic effects of 1% cyclopentolate and 0.5% tropicamide in them. null Methods null A total of 300 young adults (108 males and 192 females) aged 17 to 22 years (mean 19.03 ± 1.01) were recruited from Tianjin Medical University from November 2019 to January 2020. Participants were randomly divided into two groups. I...
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#1Di Wang (Tianjin Medical University)
#2Dejia Wen (Tianjin Medical University)
Last. Ruihua Wei (Tianjin Medical University)H-Index: 8
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Purpose: To explore how Fourier parameters are associated with axial length growth (ALG) and clinical parameters in children who underwent orthokeratology.Materials and Methods: A total of 267 children received orthokeratology. Baseline cycloplegic autorefraction was performed. Axial length was measured at baseline and one year after the lens dispatch, and the difference was defined as ALG. Corneal topography was performed at the same two visits. Central treatment zone (CTZ) was identified from ...
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#1Yanhui Chen (Tianjin Medical University)
Last. Ruihua WeiH-Index: 8
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PURPOSE To analyze the agreement of corrected intraocular pressure (IOP) values between Corvis ST (ΔIOP1) and Pentacam (ΔIOP2) in patients with keratoconus (KC), subclinical KC (sub-KC), and normal cornea. METHODS In total, 235 eyes were divided into KC, sub-KC, and control groups. Differences in ΔIOP1 (biomechanically corrected IOP minus uncorrected IOP) and ΔIOP2 (central corneal thickness-corrected amounts of IOP) were analyzed within and among groups. Topographical and biomechanical differen...
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#2Zhuzhu LiuH-Index: 1
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#1Bei Du (Tianjin Medical University)H-Index: 1
#2Jia-Lin Zheng (Nanjing Medical University)H-Index: 1
Last. Lijie Dong (Tianjin Medical University)H-Index: 11
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Bone morphogenetic proteins (BMPs), a member of the transforming growth factor β (TGF-β) superfamily, are abundant in human ocular tissues and play an important role in lens development. Targeted deletion of BMP-4 in mice results in failure of lens placode formation. Following lens maturation, the formation of senile cataracts is demonstrably associated with free radical-related oxidative stress. Previous studies reported that BMPs play an antiapoptotic role in cells under oxidative stress, and ...
2 CitationsSource
#1Chengcheng JinH-Index: 1
#2Ruxia Pei (Tianjin Medical University)
Last. Lin Liu
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#1Ying Zhu (Tianjin Medical University)H-Index: 1
#2Jingfang Bian (PolyU: Hong Kong Polytechnic University)H-Index: 2
Last. Thomas Chuen Lam (PolyU: Hong Kong Polytechnic University)H-Index: 8
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Abstract Atropine, a non-selective muscarinic antagonist, is known to slow down myopia progression in human adolescents and in several animal models. However, its underlying molecular mechanism is unclear. The present work built a monocular form-deprivation myopia (FDM) guinea pig model, using facemasks as well as atropine treatment on FDM eyes for 2 and 4 weeks. Retinal protein changes in response to the FDM and effects of topical administration of atropine were screened for the two periods usi...
1 CitationsSource
#1Guihua Liu (Vision-Sciences, Inc.)
#2Hua Rong (Tianjin Medical University)
Last. Ruihua Wei (Tianjin Medical University)H-Index: 8
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Background To investigate the new cornea biomechanical parameter stress-strain index (SSI) in Chinese healthy people and the factors associated with SSI. Methods A total of 175 eyes from 175 participants were included in this study. Axial length was measured with the Lenstar LS-900. Pentacam measured curvature of the cornea and anterior chamber volume (ACV). Cornea biomechanical properties assessments were performed by corneal visualization Scheimpflug technology (Corvis ST). Student's t-test, o...
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#1Di Wang (Tianjin Medical University)
#2Nan Jin (Tianjin Medical University)H-Index: 1
Last. Xiaorong Li (Tianjin Medical University)H-Index: 22
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Aim To evaluate the effectiveness of Grand Seiko Ref/Keratometer WAM-5500 compared to Topcon KR800 autorefractor in detecting refractive error in large scale vision screening for Chinese school age children with the WHO criteria. Methods A total of 886 participants were enrolled with mean age of 9.49±1.88y from Tianjin, China. Spherical equivalent (SE) was obtained from un-cycloplegic autorefraction and cycloplegic autorefraction. Topcon KR 800 (Topcon) and Grand Seiko WAM-5500 (WAM) autorefract...
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#1Bei Du (Tianjin Medical University)H-Index: 1
#2Nan Jin (Tianjin Medical University)H-Index: 1
Last. Ruihua Wei (Tianjin Medical University)H-Index: 8
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Abstract Background Myopia is a prevalent eye disorder, especially among children and adolescents in eastern Asian countries. Multiple measures have already been taken to prevent and treat myopia, including atropine and dopamine. However, the serum metabolic picture of myopia has not yet been studied as a whole and remains largely unclear. In this paper, a prospective and panoramic study was carried out to find out the whole serum metabolomic and lipidomic picture of myopia. Methods With untarge...
3 CitationsSource