Jianping Zheng
Hubei University
ReceptorRegeneration (biology)Gene knockdownIntensive care medicineTight junctionChemistryKeratinocyteWound healingStem cellTissue engineeringMAPK/ERK pathwayMechanism (biology)Immunoglobulin superfamilyEpidermis (botany)Cell biology
2Publications
2H-index
16Citations
Publications 2
Newest
#1Linlin Su (Fourth Military Medical University)H-Index: 18
#2Jianping Zheng (Huda: Hubei University)H-Index: 2
Last. Dahai Hu (Fourth Military Medical University)H-Index: 26
view all 5 authors...
Abstract Normal wound repair is a dynamic and complex process involving multiple coordinated interactions between growth factors, cytokines, chemokines, and various cells. Any failure during the repair process may cause chronic wounds or scar formation, which increase the financial burden of patients due to repetitive treatments and considerable medical expenditures, and affect their quality of life. Nowadays, extensive efforts have been made to develop novel therapeutics for wound repair. Genet...
11 CitationsSource
#1Yunchuan Wang (Fourth Military Medical University)H-Index: 1
#2Jianping Zheng (Huda: Hubei University)H-Index: 2
Last. Xiaobing Fu (Chinese PLA General Hospital)H-Index: 1
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Junctional adhesion molecule-A (JAM-A) belongs to the immunoglobulin superfamily, it predominantly exists at the tight junctions of epithelial and endothelial cells. JAM-A is known to regulate leukocyte trans-endothelial migration, however, how it affects the proliferation and migration of keratinocytes, the two essential steps during wound healing, has less been explored. In this study, we showed that JAM-A was significantly expressed in normal skin epidermis. RNAi-mediated JAM-A knockdown rema...
5 CitationsSource