Julieta E. Lischinsky
New York University
TransgeneSexual dimorphismSensory cueG protein-coupled receptorDevelopmental psychologyLoomingPsychologyHuman factors and ergonomicsNeuroscienceChemistryMonoamine neurotransmitterCognitive scienceInjury preventionIn vivoNeurotransmitterZebrafishHypothalamusLocus coeruleusNorepinephrineAggressionVentral tegmental areaSuperior colliculusGonadal Steroid HormonesFuture studiesAnimal speciesPoison controlInstinctOptogeneticsDopamineMidbrainNatural selectionBiologySensory systemCell biologyPredator
Publications 4
#1Julieta E. Lischinsky (NYU: New York University)H-Index: 3
#2Dayu Lin (NYU: New York University)H-Index: 22
Aggression is a social behavior essential for securing resources and defending oneself and family. Thanks to its indispensable function in competition and thus survival, aggression exists widely across animal species, including humans. Classical works from Tinbergen and Lorenz concluded that instinctive behaviors including aggression are mediated by hardwired brain circuitries that specialize in processing certain sensory inputs to trigger stereotyped motor outputs. They further suggest that ins...
18 CitationsSource
#1Julieta E. Lischinsky (NYU: New York University)H-Index: 3
#2Dayu Lin (Center for Neural Science)H-Index: 22
Threat avoidance, particularly from predators, is key for survival. Through the use of optogenetics, viral tracing, and electrophysiological recordings, Zhou and colleagues identified a superior colliculus to ventral tegmental area pathway in detecting alarming visual cues and mediating defensive behaviors in mice. These findings provide novel insight into the neural circuit underlying innate predator defense.
1 CitationsSource
#1Jiesi Feng (PKU: Peking University)H-Index: 10
#2Zhang C (CAS: Chinese Academy of Sciences)H-Index: 1
Last. Yulong LiH-Index: 21
view all 19 authors...
Summary Norepinephrine (NE) is a key biogenic monoamine neurotransmitter involved in a wide range of physiological processes. However, its precise dynamics and regulation remain poorly characterized, in part due to limitations of available techniques for measuring NE in vivo. Here, we developed a family of GPCR activation-based NE (GRABNE) sensors with a 230% peak ΔF/F0 response to NE, good photostability, nanomolar-to-micromolar sensitivities, sub-second kinetics, and high specificity. Viral- o...
130 CitationsSource
#1Koichi Hashikawa (NYU: New York University)H-Index: 4
#1Koichi Hashikawa (NYU: New York University)H-Index: 5
Last. Dayu Lin (Center for Neural Science)H-Index: 22
view all 4 authors...
Aggression is a fundamental social behavior that is essential for competing for resources and protecting oneself and families in both males and females. As a result of natural selection, aggression is often displayed differentially between the sexes, typically at a higher level in males than females. Here, we highlight the behavioral differences between male and female aggression in rodents. We further outline the aggression circuits in males and females, and compare their differences at each ci...
31 CitationsSource