Ilja Tachecí
Charles University in Prague
PharmacokineticsInternal medicineRadiologySurgeryPathologyChemistryProspective cohort studyImmunologyDouble-balloon enteroscopyCapsule endoscopyCzechEnteropathyColonoscopyEndoscopyCapsuleStomachAbdominal painEnteroscopyPopulationColorectal cancerGeneral surgeryMedicineGastroenterologyPharmacology
125Publications
16H-index
950Citations
Publications 125
Newest
#1Jan Bures (Charles University in Prague)H-Index: 28
#2Ilja Tachecí (Charles University in Prague)H-Index: 16
Last. Jana Zdarova Karasova (University of Defence)H-Index: 17
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Galantamine has been used as a treatment for Alzheimer disease. It has a unique, dual mode of action (inhibitor of acetylcholinesterase and allosteric modulator of nicotinic acetylcholine receptors). Nausea (in about 20%), vomiting (10%) and diarrhoea (5-7%) are the most common side effects. The aim of this study was to assess the effect of galantamine on porcine gastric myoelectric activity without (Group A) and with (Group B) dextran sodium sulphate (DSS)-induced gastrointestinal injury. Galan...
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#1Ilja Tachecí (Charles University in Prague)H-Index: 16
#2Marcela KopacovaH-Index: 21
Last. Jan BuresH-Index: 28
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PURPOSE OF REVIEW Peutz-Jeghers syndrome is a rare, autosomal dominant, hereditary polyposis syndrome defined by gastrointestinal hamartomas and mucocutaneous pigmentations, caused by a germline mutation in the serine/ threonine kinase 11 or liver kinase B1 (STK11/LKB1) genes. Hamartomatous polyps located throughout the gastrointestinal tract can be complicated by bleeding and small bowel intussusception, potentially leading to the need for emergency surgery. Individuals suffering from Peutz-Jeg...
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#1Ilja TachecíH-Index: 16
#2Jaroslav KvetinaH-Index: 11
Last. Jan BuresH-Index: 28
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Source
#1Jan Melek (Charles University in Prague)H-Index: 2
#2Markéta Štanclová (Charles University in Prague)H-Index: 1
Last. Jan BuresH-Index: 28
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Background Mucosal healing (MH) has become a perspective treatment target in patients with Crohn's disease (CD). Data about the impact of MH on long-term outcome in pediatric patients are still scarce. Methods 76 pediatric patients with CD were evaluated retrospectively (2000-2015) in a tertiary care center. Based on MH achievement, they were divided into two groups (MH, n= 17; and No MH, n=59). The primary endpoint was to assess the association of MH and the need for CD-related hospitalizations...
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#1Jan BuresH-Index: 28
#2Ilja TachecíH-Index: 16
Last. Jana Zdarova KarasovaH-Index: 17
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Gastrointestinal side effects of donepezil, including dyspepsia, nausea, vomiting or diarrhea, occur in 20–30% of patients. The pathogenesis of these dysmotility associated disorders has not been fully clarified yet. Pharmacokinetic parameters of donepezil and its active metabolite 6-O-desmethyldonepezil were investigated in experimental pigs with and without small intestinal injury induced by dextran sodium sulfate (DSS). Morphological features of this injury were evaluated by a video capsule e...
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#1Vladimír Bureš (University of Hradec Králové)H-Index: 9
#2Pavel Čech (University of Hradec Králové)H-Index: 6
Last. Marek Zanker (University of Hradec Králové)H-Index: 3
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Diagnostics-related errors made by medical students represent a considerable issue for the field, as they very often have negative consequences that reduce learning effectiveness. This study propos...
1 CitationsSource
#1Ilja Tachecí (Charles University in Prague)H-Index: 16
#2Rudolf Repák (Charles University in Prague)H-Index: 7
Last. Darina Kohoutova (The Royal Marsden NHS Foundation Trust)H-Index: 1
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ABSTRACT Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS) is a rare familial gastric cancer syndrome with an autosomal dominant pattern of inheritance. It is characterised by fundic gland polyposis of the gastric body and is associated with a significant risk of gastric adenocarcinoma. Unlike sporadic gastric cancer, Helicobacter pylori is usually absent in patients with GAPPS. This opposite-point finding has so far not been fully clarified. Prophylactic total gastrectomy is ...
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Introduction A proactive approach is recommended in colorectal anastomosis leak treatment, and early diagnosis is very important. Early postoperative endoscopy would allow rapid diagnosis of anastomotic pathologies and consequent prompt intervention according to anastomotic disruption morphology. Aim To evaluate the effectiveness of close endoscopic follow-up of all patients (including asymptomatic ones) in improving diagnosis of acute leak (AL) and reducing its complications. Material and metho...
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#1Samir Jain (Indian Institute of Information Technology, Design and Manufacturing, Jabalpur)H-Index: 1
#2Ayan Seal (Indian Institute of Information Technology, Design and Manufacturing, Jabalpur)H-Index: 13
Last. Anis Yazidi (Metropolitan University)H-Index: 11
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Abstract One of the most recent non-invasive technologies to examine the gastrointestinal tract is wireless capsule endoscopy (WCE). As there are thousands of endoscopic images in an 8–15 h long video, an evaluator has to pay constant attention for a relatively long time (60–120 min). Therefore the possibility of the presence of pathological findings in a few images (displayed for evaluation for a few seconds only) brings a significant risk of missing the pathology with all negative consequences...
2 CitationsSource
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Dieulafoy lezia je vzacna pricina krvacania do traviaceho traktu z minimalneho defektu erodovanej submukoznej arterie. Najcastejsie býva lokalizovana v žaludku u starsich polymorbidnych mužov, može sa vsak vyskytovať v celom traviacom trakte, u obidvoch pohlavi a v každom veku. Malo by sa na ňu myslieť, ako na jednu z možných pricin krvacania z neurceneho zdroja. Krvacanie je casto masivne, vyžadujuce rýchlu diagnostiku, liecbu a mutidisciplinarny pristup. Kazuistika popisuje pripad pacienta s r...