Gregory I Snell
Monash University
Internal medicineSurgeryPathologyCardiologyRetrospective cohort studyIntensive care medicineImmunologyDonationRespiratory diseaseBronchiolitis obliteransCOPDLungBronchoalveolar lavageImmunosuppressionLung transplantationPrimary Graft DysfunctionTransplantationAnesthesiaMedicineGastroenterology
429Publications
60H-index
9,266Citations
Publications 428
Newest
#1Michael Z L Zhu (Alfred Hospital)
#2Joanna Yilin Huang (Alfred Hospital)
Last. Gregory I Snell (Alfred Hospital)H-Index: 60
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A best evidence topic was written according to a structured protocol. The question addressed was: 'Does continuation of antifibrotics before lung transplantation (LTx) influence post-transplant outcomes in patients with idiopathic pulmonary fibrosis (IPF) with regard to mortality, bronchial anastomotic dehiscence, reoperation for bleeding and wound complications, primary graft dysfunction or longer-term survival and allograft rejection?' A total of 261 articles were found using the reported sear...
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#1Miranda Paraskeva (Alfred Hospital)H-Index: 13
#2Brigitte M. Borg (Monash University)H-Index: 9
Last. Gregory I Snell (Monash University)H-Index: 60
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Background null The prognostic value of evaluating spirometry at a fixed time point using standardized population reference has not previously been evaluated. Our aim was to assess the association between spirometric phenotype at 12 months (Spiro12M), survival and incidence of chronic lung allograft dysfunction (CLAD) in bilateral lung transplant recipients. null null null Methods null We conducted a retrospective cohort study of bilateral lung transplant recipients transplanted between January ...
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#1Shuji Okahara (Monash University)H-Index: 1
#2Bronwyn Levvey (Monash University)H-Index: 38
Last. Gregory I Snell (Monash University)H-Index: 60
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Abstract Background Even in the extended-criteria era, the reasons for declining lung donors are not always clear. Furthermore, it has not been determined how many actual declined lungs would be retrieved by ex-vivo lung perfusion (EVLP) beyond that already achieved in centers with an existing high utilization rate. Methods This retrospective study reviewed all lung donor referrals between 2014-2018, including detailed formal referrals and preliminary notifications. This study categorized reason...
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#1Shuji Okahara (Monash University)H-Index: 1
#2Bronwyn Levvey (Monash University)H-Index: 38
Last. Gregory I Snell (Monash University)H-Index: 60
view all 7 authors...
Background null In Australia, increased organ donation and subsequent lung transplantation (LTx) rates have followed enhanced donor identification, referral and management, as well as the introduction of a donation after circulatory death (DCD) pathway. However, the number of patients waiting for LTx still continues to exceed the number of lung donors and the search for further suitable donors is critical. null null null Methods null All 2014–2018 Victorian DonateLife hospital deaths after inten...
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#1Jaideep Vazirani (Monash University)H-Index: 1
#2Glen P. Westall (Monash University)H-Index: 29
Last. C. Orla Morrissey (Monash University)H-Index: 16
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INTRODUCTION Scedosporium apiospermum and Lomentospora prolificans (Scedosporium/Lomentospora) species are emerging, multi-resistant pathogens that cause life-threatening illnesses among lung transplant (LTx) recipients. The current epidemiology and management in LTx are unknown. METHODS We performed a retrospective single center audit of all sputum/bronchoscopy samples for Scedosporium/Lomentospora species in LTx patients over a 24-year period (1995-2019). Patients were diagnosed as colonized o...
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#1Shuji Okahara (Monash University)H-Index: 1
#2Gregory I Snell (Monash University)H-Index: 60
Last. Bronwyn Levvey (Monash University)H-Index: 38
view all 7 authors...
Although the use of donation-after-circulatory-death (DCD) donors has increased lung transplant activity, 25-40% of intended DCD donors do not convert to actual donation due to no progression to asystole in the required timeframe after withdrawal of cardio-respiratory support (WCRS). No studies have specifically focused on DCD lung donor progression. This retrospective study reviewed intended DCD lung donors to make a prediction model of the likelihood of progression to death using logistic regr...
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Purpose A retrospective study of paediatric lung and heart-lung transplant (LTx) recipients to assess growth and its relationship with spirometric indices. Methods Analyses of relationships between serially assessed age, height, weight, forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1) were undertaken. Serial spirometry at identical heights were analysed as means. Percentile height-for-age was calculated from the CDC 2000 dataset.1 95% confidence intervals are presented...
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Purpose Baseline and chronic lung allograft dysfunction (BLAD & CLAD) are leading causes of reduced patient survival. Airway oscillometry characterises the lung's mechanical properties with greater sensitivity than spirometry. This study aims to characterise BLAD and CLAD with airway oscillometry. Methods Oscillometry was performed on all bilateral lung transplant (LTx) recipients at 2 Australian centres between Jan-Oct 2020 with the TremoFlo C-100 device to obtain resistance (R5, R19-5), reacta...
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#1Bronwyn Levvey (Alfred Hospital)H-Index: 38
#2S. Okahara (Okayama University)
Last. Gregory I Snell (Alfred Hospital)H-Index: 60
view all 7 authors...
Purpose Although use of donation-after-circulatory-death (DCD) donors has significantly increased lung transplant (LTx) rates, 25-40% of intended DCD do not convert to actual donors due to non-progression to asystole in the required 90 minute time frame from withdrawal of cardio-respiratory support (WCRS). Predicting which intended DCD patient will progress remains problematic & impacts resourcing. Methods This retrospective study reviewed intended DCD lung donors referred between 2014-2018 to o...
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