Christina Hague
University of Manchester
Deep learningPhase (waves)CancerInternal medicineRadiologyMagnetic resonance imagingOncologyCellArtificial intelligenceDose fractionationProspective cohort studyMasticatory forceDentistryProstateHead and neck cancerClinical OncologyAtlas (anatomy)CarcinomaMuscles of masticationTrismusContouringProton therapyRadium-223Castrate-resistant prostate cancerLeft submandibular glandOrthodonticsOrgan at riskOral cavityNuclear medicinePublic involvementMulticenter studyCt planningProspective evaluationRadiotherapy doseImproved performanceHead and neck radiotherapySurvey resultIntensity modulated radiotherapyClinical evaluationObserver variationPost operativeRadiation therapyFamily medicineClinical trialMedicineIntensity (physics)
12Publications
3H-index
26Citations
Publications 12
Newest
#1Christina HagueH-Index: 3
#2Andrew McPartlinH-Index: 6
Last. R. Chuter (MAHSC: Manchester Academic Health Science Centre)
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Abstract Introduction Auto contouring models help consistently define volumes and reduce clinical workload. This study aimed to evaluate the cross acquisition of a Magnetic Resonance (MR) deep learning auto contouring model for organ at risk (OAR) delineation in head and neck radiotherapy. Methods Two auto contouring models were evaluated using deep learning contouring expert (DLCExpert) for OAR delineation: a CT model (modelCT) and an MR model (modelMRI). Models were trained to generate auto co...
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#1Emma HallH-Index: 57
#2Christina HagueH-Index: 3
Last. Nicholas J SlevinH-Index: 35
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#1Christina HagueH-Index: 3
#2William J BeasleyH-Index: 4
Last. Robert ChuterH-Index: 19
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Source
#1Christina Hague (University of Manchester)H-Index: 3
#2Marianne C. Aznar (University of Manchester)H-Index: 31
Last. Boon-Keng Kevin Teo (UPenn: University of Pennsylvania)H-Index: 21
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Objectives:To evaluate dosimetric consequences of inter fraction set up variation and anatomical changes in patients receiving multi field optimised (MFO) intensity modulated proton therapy for pos...
3 CitationsSource
#1Christina HagueH-Index: 3
#2William J BeasleyH-Index: 4
Last. Nicholas J SlevinH-Index: 35
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Abstract Purpose/objective(s) Trismus is caused by injury to the masticatory muscles resulting from cancer or its treatment. Contouring these muscles to reduce dose and radiation related trismus can be problematic due to interobserver variability. This study aimed to evaluate the reduction in interobserver variability achievable with a new contouring atlas. Materials/methods The atlas included: medial and lateral pterygoids (MP, LP), masseter (M) and temporalis (T) muscles, and the temporo-mandi...
5 CitationsSource
Source
#1Christina HagueH-Index: 3
#2Bernadette Foran (Weston Park Hospital)H-Index: 7
Last. David J ThomsonH-Index: 11
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7 CitationsSource
#1Christina HagueH-Index: 3
#2William J BeasleyH-Index: 4
Last. Nicholas J SlevinH-Index: 35
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AbstractAims: This feasibility study aimed to identify relationships between radiation doses to the masticatory apparatus as a combined block or as individual subunits with changes in trismus following radiotherapy.Material and methods: Twenty patients from a single center were recruited prospectively as part of a randomized trial comparing proactive exercises in the management of trismus. Patients with stage III/IV oral cavity or oropharyngeal squamous cell cancers received intensity-modulated ...
3 CitationsSource
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#1Christina HagueH-Index: 3
#2Alan McWilliamH-Index: 12
Last. N. SlevinH-Index: 9
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