Jinsoo Kim
Hallym University
OphthalmologySurgeryVirologyAntibodyChemistryApoptosisIn vitroVirusInfluenza A virusB cellPeritoneal cavitySTAT3PeptideEyelidIn patientMedicineCell cultureBiologyImmune systemVero cell
Publications 21
#1Byoung Kwon Park (Hallym University)H-Index: 9
#2Dongbum Kim (Hallym University)H-Index: 13
Last. Hyung-Joo Kwon (Hallym University)H-Index: 19
view all 9 authors...
Severe acute respiratory syndrome CoV-2 (SARS-CoV-2) is responsible for the current coronavirus disease 2019 (COVID-19) pandemic. Signaling pathways that are essential for virus production have potential as therapeutic targets against COVID-19. In this study, we investigated cellular responses in two cell lines, Vero and Calu-3, upon SARS-CoV-2 infection and evaluated the effects of pathway-specific inhibitors on virus production. SARS-CoV-2 infection induced dephosphorylation of STAT1 and STAT3...
2 CitationsSource
#1Dongbum Kim (Hallym University)H-Index: 13
#2Sony Maharjan (Hallym University)H-Index: 6
Last. Hyung-Joo Kwon (Hallym University)H-Index: 19
view all 8 authors...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces coronavirus disease 2019 (COVID-19) and may increase the risk of adverse outcomes in lung cancer patients. In this study, we investigated the expression and function of mucin 1 (MUC1) after SARS-CoV-2 infection in the lung epithelial cancer cell line Calu-3. MUC1 is a major constituent of the mucus layer in the respiratory tract and contributes to pathogen defense. SARS-CoV-2 infection induced MUC1 C-terminal subunit (MUC1-C) e...
#1Byoung Kwon ParkH-Index: 9
#2Jin-Soo KimH-Index: 15
Last. Hyung-Joo KwonH-Index: 19
view all 11 authors...
Background: The molecular interactions between viral proteins form the basis of virus production and can be used to develop strategies against virus infection. The interactions of the envelope proteins and the viral RNA-binding nucleocapsid (N) protein are essential for the assembly of coronaviruses including the Middle East respiratory syndrome coronavirus (MERS-CoV). Methods: Using co-immunoprecipitation, immunostaining, and proteomics analysis, we identified a protein interacting with the spi...
1 CitationsSource
#1Minji Ha (Catholic University of Korea)H-Index: 2
#2Jin Soo Kim (Sacred Heart Hospital)
Last. Ho Sik Hwang (Catholic University of Korea)H-Index: 5
view all 9 authors...
Abstract Purpose To examine the relationship between lid margin abnormalities and meibomian gland loss in infrared meibography. Methods This study was a retrospective chart review of 170 patients with dry eye disease. A correlation analysis between eyelid margin abnormalities and meibomian gland dropout in infrared meibography was performed using data from 141 eyes. We graded the following eyelid margin abnormalities: irregular lid margin, vascular engorgement, plugging, anterior placement of th...
#1Jinsoo Kim (Sacred Heart Hospital)H-Index: 3
#2In Won Park (Sacred Heart Hospital)H-Index: 9
Last. Soonil Kwon (Sacred Heart Hospital)H-Index: 13
view all 3 authors...
To investigate factors reflecting visual outcome and macular perfusion in quiescent proliferative diabetic retinopathy (PDR) patients after panretinal photocoagulation (PRP). We included 118 patients with quiescent PDR who had completed PRP. All participants had standardized interview to determine ocular history, smoking status, cardiovascular risk factors, and history of diabetic mellitus (DM). Foveal avascular zone (FAZ) area, retinal vessel density (VD) and vessel length density (VLD) were me...
1 CitationsSource
#1Madhav Akauliya (Hallym University)H-Index: 2
#2Avishekh Gautam (Hallym University)H-Index: 4
Last. Hyung-Joo Kwon (Hallym University)H-Index: 19
view all 6 authors...
CD83 is known to regulate lymphocyte maturation, activation, homeostasis, and antibody response to immunization and infection. While CD83 has a major part in B cell function, its role in influenza A virus infection has not yet been investigated. We investigated the role of CD83 using C57BL/6J wild type mice and CD83 knockout (KO) mice after intraperitoneal administration of the influenza A/WSN/1933 virus. We analyzed cells of the peritoneal cavity, splenocytes, and cells of the bone marrow with ...
1 CitationsSource
#1Avishekh GautamH-Index: 4
#2Madhav AkauliyaH-Index: 2
Last. Hyung Joo Kwon (Hallym University)H-Index: 15
view all 12 authors...
In humans, respiratory infections with influenza A viruses can be lethal, but it is unclear whether non-respiratory influenza A infections can be equally lethal. Intraperitoneal infection makes the abdominal and pelvic organs accessible to pathogens because of the circulation of peritoneal fluid throughout the pelvis and abdomen. We found that high-dose intraperitoneal infection in mice with influenza A viruses resulted in severe sclerosis and structural damage in the pancreas, disruption of ova...
1 CitationsSource
#1Gye Jung Kim (Sacred Heart Hospital)
#2Dong Hwan Son (Sacred Heart Hospital)
Last. Min Chul Shin (Hallym University)H-Index: 3
view all 4 authors...
#1Yong Ho Koo (Sacred Heart Hospital)
#2Chang Su Lee (University of Suwon)
Last. Ho Sik Hwang (Catholic University of Korea)H-Index: 5
view all 7 authors...
#1Kwan Hyuk Cho (Sacred Heart Hospital)
#2Jinsoo Kim (Sacred Heart Hospital)H-Index: 3
Last. Joo Yeon Lee (Sacred Heart Hospital)H-Index: 8
view all 4 authors...
PURPOSE: Most ophthalmologists appear to have no distinct preference between unilateral recess-resect (R&R) and bilateral lateral rectus (BLR) recessions to treat basic-type exotropia. This study aimed to determine whether differences in distance-near discrepancy and resultant exotropia types of recurrent exotropia following surgery for primary basic-type exotropia exist between the two surgical options. METHODS: Ninety-three patients with recurrent exotropia following BLR recessions for basic-t...