Fergus Gleeson
John Radcliffe Hospital
Publications 11
#1Andrew G. Murchison (John Radcliffe Hospital)H-Index: 6
#2Julie-Ann Moreland (John Radcliffe Hospital)
Last. Fergus V. Gleeson (John Radcliffe Hospital)H-Index: 58
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Abstract Rationale and objectives To determine the prevalence of incidental findings and define the rate and outcomes of further investigations in a referral pathway for patients with non-specific cancer symptoms. Material and methods Incidental findings in each category of a structured report were documented and details of subsequent investigations were obtained from the local PACS and Electronic Patient Record system. Results 1034 patients were included. Of these, 11% were diagnosed with cance...
#1Maria Tsakok (John Radcliffe Hospital)H-Index: 7
#1Maria Tsakok (John Radcliffe Hospital)H-Index: 2
Last. Rachel BenamoreH-Index: 5
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#1Maria Tsakok (John Radcliffe Hospital)H-Index: 7
#1Maria Tsakok (John Radcliffe Hospital)H-Index: 2
Last. Fergus V. Gleeson (John Radcliffe Hospital)H-Index: 58
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Abstract Purpose To determine how implementation of an artificial intelligence nodule algorithm, the Lung Cancer Prediction Convolutional Neural Network (LCP-CNN), at the point of incidental nodule detection would have influenced further investigation and management using a series of threshold scores at both the benign and malignant end of the spectrum. Method An observational retrospective study was performed in the assessment of nodules between 5-15 mm (158 benign, 32 malignant) detected on CT...
#1M.R. Chetan (John Radcliffe Hospital)H-Index: 1
#2Maria Tsakok (John Radcliffe Hospital)H-Index: 7
Last. Fergus Gleeson (John Radcliffe Hospital)H-Index: 6
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Abstract Aim To determine the incidence of possible COVID-19-related lung changes on preoperative screening computed tomography (CT) for COVID-19 and how their findings influenced decision-making and to determine whether the patients were managed as COVID-19 patients after their imaging findings, and the proportion who had SARS-CoV2 reverse transcription-polymerase chain reaction (RT-PCR) testing. Materials and methods A retrospective study was undertaken of consecutive patients having imaging p...
10 CitationsSource
#1David J. McCrackenH-Index: 4
#2Najib M. RahmanH-Index: 46
Last. Fergus GleesonH-Index: 2
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#1Simon Lord (John Radcliffe Hospital)H-Index: 11
#2Neel Patel (John Radcliffe Hospital)H-Index: 7
Last. Adrian L. Harris (John Radcliffe Hospital)H-Index: 191
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There has been growing interest in the potential of the altered metabolic state typical of cancer cells as a drug target. The antidiabetes drug, metformin, is now under intense investigation as a safe method to modify cancer metabolism. Several studies have used window of opportunity in breast cancer patients before neoadjuvant chemotherapy to correlate gene expression analysis, metabolomics, immunohistochemical markers, and metabolic serum markers with those likely to benefit. We review the rol...
7 CitationsSource
#1Auditi Naziat (Churchill Hospital)H-Index: 2
#2Niki Karavitaki (Churchill Hospital)H-Index: 38
Last. Brian Shine (University of Oxford)H-Index: 23
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19 CitationsSource
#1John M. Wrightson (Churchill Hospital)H-Index: 2
#1John M. Wrightson (Churchill Hospital)H-Index: 19
Last. Nick A Maskell (UoB: University of Bristol)H-Index: 51
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Funding/Support: Dr Restrepo is partially funded by the National Heart, Lung, and Blood Institute [K23HL096054]. Financial/nonfinancial disclosures: The authors have reported to CHEST the following conflicts of interest: Dr Restrepo is a former participant in advisory boards for Theravance Inc; Forest Laboratories, Inc; Johnson & Johnson Services, Inc; Trius Therapeutics; and Novartis AG and has been a consultant for Theravance Inc; Trius Therapeutics; and Pfizer, Inc. Drs Fernandez and Levine h...
3 CitationsSource
#1Najib M. RahmanH-Index: 46
#2Nick A Maskell (North Bristol NHS Trust)H-Index: 51
Last. Robert J. O. DaviesH-Index: 76
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Background The optimal choice of chest tube size for the treatment of pleural infection is unknown, with only small cohort studies reported describing the efficacy and adverse events of different tube sizes. Methods A total of 405 patients with pleural infection were prospectively enrolled into a multicenter study investigating the utility of fibrinolytic therapy. The combined frequency of death and surgery, and secondary outcomes (hospital stay, change in chest radiograph, and lung function at ...
140 CitationsSource
#1Radu Mihai (John Radcliffe Hospital)H-Index: 27
#2Mary Weisters (John Radcliffe Hospital)H-Index: 2
Last. Greg Sadler (John Radcliffe Hospital)H-Index: 8
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Background Concordant parathyroid localization with sestamibi and ultrasound scans allows minimally invasive parathyroidectomy (MIP) to be performed in patients with non-familial primary hyperparathyroidism (PHPT).
11 CitationsSource