Leon Fisher
Frankston Hospital
CancerRisk assessmentVitamin D and neurologyN-terminal telopeptideInternal medicineOsteocalcinUnivariate analysisRenal functionBone remodelingIntensive care medicineMortality rateAdverse effectObservational studyHyperparathyroidismHypoalbuminemiaAlbuminHelicobacter pyloriOsteoporosisSpontaneous bacterial peritonitisPneumonia (non-human)Heart failureKidney diseaseHip fractureImmunityMalignancyDiarrheaAtrophic gastritisPopulationPredictive valueMean ageNarrative reviewRoutine laboratoryIn hospital mortalityIncidence (epidemiology)Linear regressionPharmacotherapyLiver function testsProcollagen peptidaseBone resorptionMedicineGastroenterology
Publications 5
#1Leon Fisher (Frankston Hospital)H-Index: 4
#2Alexander A. Fisher (Canberra Hospital)H-Index: 20
Last. Paul N. SmithH-Index: 36
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Osteoporosis (OP) and osteoporotic fractures (OFs) are common multifactorial and heterogenic disorders of increasing incidence. Helicobacter pylori (H.p.) colonizes the stomach approximately in half of the world’s population, causes gastroduodenal diseases and is prevalent in numerous extra-digestive diseases known to be associated with OP/OF. The studies regarding relationship between H.p. infection (HPI) and OP/OFs are inconsistent. The current review summarizes the relevant literature on the ...
2 CitationsSource
#1Alexander Fisher (ANU: Australian National University)H-Index: 12
#1Alexander Fisher (Canberra Hospital)H-Index: 12
Last. Paul N. Smith (ANU: Australian National University)H-Index: 36
view all 4 authors...
Abstract Introduction The data on predictive value of the routinely obtained preoperative biochemical parameters in hip fracture (HF) patients are limited. The aims of this study were to examine in older HF patients (1) the relationships between a broad set of routine laboratory parameters at admission and in-hospital mortality, and (2) evaluate the prognostic value the biomarkers and clinical characteristics (alone or in combination) provide to predict a fatal outcome. Patients and methods In 1...
8 CitationsSource
#1Alexander Fisher (ANU: Australian National University)H-Index: 12
#2Leon Fisher (Frankston Hospital)H-Index: 4
Last. Paul N. Smith (Canberra Hospital)H-Index: 36
view all 4 authors...
Aim: To develop a practical model for classification bone turnover status and evaluate its clinical usefulness. Methods: Our classification of bone turnover status is based on internationally recommended biomarkers of both bone formation (N-terminal propeptide of type1 procollagen, P1NP) and bone resorption (beta C-terminal cross-linked telopeptide of type I collagen, bCTX), using the cutoffs proposed as therapeutic targets. The relationships between turnover subtypes and clinical characteristic...
10 CitationsSource
#1Alexander Fisher (ANU: Australian National University)H-Index: 12
#1Alexander A. Fisher (Canberra Hospital)H-Index: 20
Last. Paul N. Smith (Canberra Hospital)H-Index: 36
view all 4 authors...
PURPOSE: To estimate the discriminative value of serum P1NP/βCTX ratio and albumin levels in hospitalized orthogeriatric patients with and without nonvertebral fractures. METHODS: In 1,239 orthogeriatric patients (mean age 78.1±9.52 years, 69.1% women) including 854 (68.9%) with osteoporotic nonvertebral fractures (455 [36.7%] with hip fracture [HF]) and 385 (31.1%) without fractures, markers of bone formation (procollagen type 1 N-terminal propeptide [P1NP], osteocalcin [OC], and bone resorptio...
9 CitationsSource
#1Leon Fisher (Frankston Hospital)H-Index: 4
#2Alexander Fisher (ANU: Australian National University)H-Index: 12
Last. Alexander Fisher (Canberra Hospital)H-Index: 12
view all 2 authors...
This narrative review summarises the benefits, risks and appropriate use of acid-suppressing drugs (ASDs), proton pump inhibitors and histamine-2 receptor antagonists, advocating a rationale balanced and individualised approach aimed to minimise any serious adverse consequences. It focuses on current controversies on the potential of ASDs to contribute to infections—bacterial, parasitic, fungal, protozoan and viral, particularly in the elderly, comprehensively and critically discusses the growin...
12 CitationsSource