Hongmei Yang
Shenyang Pharmaceutical University
MicelleMass spectrometryFourier transform ion cyclotron resonanceNanocarriersChemistryDecoctionIn vitroRadixIn vivoSide effectFormic acidGinsengMitomycin CIbuprofenContext (language use)TriterpeneAntineoplastic AntibioticChromatographyPharmacology
Publications 2
#1Hongmei Yang (SPU: Shenyang Pharmaceutical University)H-Index: 1
#2Miao Wang (SPU: Shenyang Pharmaceutical University)H-Index: 9
Last. Min Zhao (SPU: Shenyang Pharmaceutical University)H-Index: 8
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Mitomycin C (MMC), naturally synthesized by Streptomyces caespitosus, is a potent antineoplastic antibiotic for the treatment of various solid tumors. However, the defects of conventional MMC injections have greatly limited its clinical application due to its toxic side effects and non-specific interactions. To solve this problem, the PEG2k-Fmoc-Ibuprofen (PEG-FIbu) micellar nanocarrier was synthesized and the MMC-loaded micelles (PEG-FIbu/MMC) were prepared by thin film hydration method and cha...
1 CitationsSource
#1Zhibo Guan (SPU: Shenyang Pharmaceutical University)H-Index: 2
#2Miao Wang (SPU: Shenyang Pharmaceutical University)H-Index: 9
Last. Chunjie Zhao (SPU: Shenyang Pharmaceutical University)H-Index: 6
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Abstract Sijunzi decoction, a renowned Chinese prescription has long been utilized to treat gastrointestinal problems. In the context of this research work, the use of Ultra high performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry was made to separate and characterize the components of Sijunzi decoction. The performance of Liquid chromatography was carried out on a C8 column (150 mm × 2.1 mm, 1.8 μm); moreover, the mobile phase were consist...
10 CitationsSource