Sophia Khan
Rowan University
Endothelial stem cellPathologyMesenchymal stem cellAneurysmEndovascular aneurysm repairVascular endothelial growth factorAortic aneurysmOpen aortic surgeryMatrigelCD31Abdominal aortic aneurysmWound healingAngiogenesisStem cellPlatelet Endothelial Cell Adhesion MoleculeEndothelial cell differentiationSurgical repairMedicineFibroblast growth factorCell biology
3Publications
2H-index
33Citations
Publications 3
Newest
#1Sophia Khan (Rowan University)H-Index: 2
#2Miguel Villalobos (Rowan University)H-Index: 2
Last. Ping Zhang (Rowan University)H-Index: 2
view all 8 authors...
Objective Adipose-derived stem cells (ASCs) are a potential adult mesenchymal stem cell source for restoring endothelial function in patients with critical limb ischemia. Fibroblast growth factor 2 (FGF2) and vascular endothelial growth factor (VEGF) play a major role in angiogenesis and wound healing. This study evaluated the effects of FGF and VEGF on the proliferation, migration, and potential endothelial differentiation of human ASCs with regards to their use as endothelial cell substitutes....
28 CitationsSource
#1Sophia Khan (Rowan University)H-Index: 2
#2Joseph V. Lombardi (Rowan University)H-Index: 12
Last. Francis J. Caputo (Rowan University)H-Index: 9
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Objective Recent advances in endovascular aneurysm repair have overcome substantial anatomic barriers associated with short and challenging necks. With greater range to treat more difficult anatomy from an endovascular approach, one would assume the need of open surgical repair (OSR) would be diminished. The purpose of our study was to determine the need for OSR for abdominal aortic aneurysms, in a tertiary academic setting, with a moderate volume (10-15 cases/year) of fenestrated endografting b...
3 CitationsSource
#1Sophia Khan (Rowan University)H-Index: 2
#2Miguel Villalobos (Rowan University)H-Index: 2
Last. Ping Zhang (Rowan University)H-Index: 2
view all 9 authors...
Background: Adipose-derived stem cells (ASCs) are a potential adult mesenchymal stem cell source for restoring endothelial function in critical limb ischemia patients. Fibroblast growth factors (FGF) play a major role in angiogenesis and wound healing. The purpose of this study was to evaluate the effects of FGF and VEGF on human ASCs proliferation, migration and potential endothelial differentiation regards to their use as endothelial cell (EC) substitutes. Methods: ASCs were isolated from clin...