Kaitlin A. Quinn
National Institutes of Health
Internal medicineRadiologyObservational studyPositron emission tomographyVasculitisAneurysmGiant cell arteritisTocilizumabRelapsing polychondritisMagnetic resonance angiographyTakayasu's arteritisStenosisAngiographyArteritisLarge vessel vasculitisNuclear medicineClinical trialMedicineCohortGastroenterology
35Publications
9H-index
174Citations
Publications 36
Newest
#1Yiming Luo (NIH: National Institutes of Health)
#2Ertugrul C. Bolek (NIH: National Institutes of Health)
Last. Marcela A. Ferrada (NIH: National Institutes of Health)H-Index: 8
view all 14 authors...
ABSTRACT null null Objective null Mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome is characterized by overlapping features of relapsing polychondritis (RP) and Behcet's disease (BD). To date, no studies have defined the clinical spectrum of disease in a cohort of patients with MAGIC syndrome. null null null Methods null Adult patients within an ongoing prospective, observational cohort study in RP were clinically assessed for MAGIC syndrome. A systematic review was conducted to...
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#1Emily Rose (NIH: National Institutes of Health)H-Index: 1
#2Marcela A. Ferrada (NIH: National Institutes of Health)H-Index: 8
Last. Peter C. Grayson (NIH: National Institutes of Health)H-Index: 27
view all 10 authors...
Objectives null Relapsing polychondritis (RP) is a rare, heterogeneous, systemic inflammatory disease that targets cartilage. Patient-reported outcome measures may differ from physician assessment. This study compared patient global assessment (PtGA) and physician global assessment (PhGA) scores in a prospective cohort of patients with RP. null Methods null Adult patients with RP underwent a standardized comprehensive evaluation at ∼6-month intervals. At each visit, three physicians scored PhGA ...
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#1Kaitlin A. Quinn (NIH: National Institutes of Health)H-Index: 9
#2H. Dashora (NIH: National Institutes of Health)H-Index: 2
Last. Peter C. Grayson (NIH: National Institutes of Health)H-Index: 27
view all 5 authors...
OBJECTIVES To evaluate the time-dependent effects of tocilizumab on vascular inflammation as measured by 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) in giant cell arteritis (GCA). METHODS Patients with GCA treated with tocilizumab were selected from a prospective, observational cohort. Patients underwent FDG-PET at the baseline visit prior to initiation of tocilizumab and at subsequent follow-up visits performed at 6-month intervals. All imaging findings were interpreted blinde...
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#9Beverley Shea (Ottawa Hospital Research Institute)H-Index: 20
Abstract null null Objective null The Outcome Measures in Rheumatology (OMERACT) Vasculitis Working Group aims to develop composite response criteria for ANCA-Associated Vasculitis (AAV). null null null Methods null The project follows the OMERACT approach for composite measures: (i) choose relevant domains; (ii) define high-quality instruments; (iii) decide on a scoring system approach; (iv) put through the OMERACT Filter 2.1 for validation. null null null Results null A systematic literature r...
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#1H. Dashora (NIH: National Institutes of Health)H-Index: 2
#2Joel S. Rosenblum (NIH: National Institutes of Health)H-Index: 6
Last. Peter C. Grayson (NIH: National Institutes of Health)H-Index: 27
view all 8 authors...
The study rationale was to assess the performance of qualitative and semi-quantitative scoring methods for 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) assessment in large-vessel vasculitis (LVV). Methods: Patients with giant cell arteritis (GCA) or Takayasu's arteritis (TAK) underwent clinical and imaging assessment, blinded to each other, within a prospective observational cohort. FDG-PET-CT scans were interpreted for active vasculitis by central reader assessment. Arterial FD...
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#1Kaitlin A. Quinn (NIH: National Institutes of Health)H-Index: 9
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#1Marcela A. Ferrada (NIH: National Institutes of Health)H-Index: 8
#2Keith A. Sikora (NIH: National Institutes of Health)H-Index: 7
Last. Peter C. Grayson (NIH: National Institutes of Health)H-Index: 27
view all 35 authors...
OBJECTIVE Somatic mutations in ubiquitin activating enzyme 1 (UBA1) cause a newly defined syndrome known as VEXAS. More than fifty percent of patients currently identified with VEXAS meet diagnostic criteria for relapsing polychondritis (RP). Clinical features that characterize VEXAS within a cohort of RP have not been defined. METHODS Exome and targeted sequencing of the UBA1 gene was performed in a prospective observational cohort of patients with RP. Clinical and immunological characteristics...
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#1Emily Rose (NIH: National Institutes of Health)H-Index: 1
#2Marcela A. Ferrada (NIH: National Institutes of Health)H-Index: 8
Last. Peter C. Grayson (NIH: National Institutes of Health)H-Index: 27
view all 12 authors...
OBJECTIVE Relapsing polychondritis (RP) is a systemic inflammatory disorder of cartilage that lacks validated disease activity measures. Physician global assessment (PhGA), a measure of disease activity commonly used in rheumatologic diseases, has not been tested in a cohort of patients with RP. METHODS Adult patients in an observational cohort of RP underwent standardized, comprehensive evaluation at approximately 6-month intervals. PhGA was scored by three physicians from the evaluating instit...
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