Patricio Araos
Autonomous University of Chile
Internal medicineEndocrinologyRenal functionProinflammatory cytokineChemistryAcquired immune systemImmunologyInflammationKidneyFibrosisAngiotensin IISodiumAntigen-presenting cellMedicineBlood pressureImmune systemPharmacology
15Publications
3H-index
38Citations
Publications 8
Newest
#2Patricio AraosH-Index: 3
Last. Cristián A. AmadorH-Index: 10
view all 6 authors...
Renal diseases are a global health concern, and nearly 24% of kidney disease patients are overweight or obese. Particularly, increased body mass index has been correlated with oxidative stress and urinary albumin excretion in kidney disease patients, also contributing to increased cardiovascular risk. Albumin is the main plasma protein and is able to partially cross the glomerular filtration barrier, being reabsorbed mainly by the proximal tubule through different mechanisms. However, it has bee...
Source
The sodium is essential for life in humans, where its balance is determined mainly by kidney function and by it consume that depends on social culture and people behavior...
Source
#1Hernán PratH-Index: 6
#2Patricio AraosH-Index: 3
Last. Luis MicheaH-Index: 24
view all 3 authors...
Source
Source
#1Patricio Araos (Autonomous University of Chile)H-Index: 3
Last. Cristián A. AmadorH-Index: 10
view all 3 authors...
It is well accepted that the immune system and some cells from adaptive and innate immunity are necessary for the initiation/perpetuation of arterial hypertension (AH). However, whether neutrophils are part of this group remains debatable. There is evidence showing that the neutrophil/lymphocyte ratio correlates with AH and is higher in non-dipper patients. On the other hand, the experimental neutrophil depletion in mice reduces basal blood pressure. Nevertheless, their participation in AH is st...
Source
#1Jessica LiberonaH-Index: 1
#2Patricio AraosH-Index: 3
Last. Luis MicheaH-Index: 24
view all 5 authors...
Introduction: Metabolic studies showed that, in addition to sodium, the intake of chloride is necessary for the development of hypertension due to high salt diet or mineralocorticoids Hypothesis: C...
#1Patricio Araos (University of Chile)H-Index: 3
#2Carolina PradoH-Index: 16
Last. Cristián A. AmadorH-Index: 10
view all 11 authors...
BACKGROUND: Adaptive immunity is crucial in cardiovascular and renal inflammation/fibrosis upon hyperactivation of mineralocorticoid receptor. We have previously demonstrated that dendritic cells can respond to mineralocorticoid receptor activation, and the neutrophil gelatinase-associated lipocalin (NGAL) in dendritic cells is highly increased during aldosterone (Aldo)/mineralocorticoid receptor-dependent cardiovascular damage. However, the interrelationship among dendritic cells, target organs...
Source
#2Patricio AraosH-Index: 3
#3Carolina PradoH-Index: 16
Last. Luis MicheaH-Index: 24
view all 11 authors...
Increasing evidence shows that antigen-presenting cells (APCs) are involved in the development of inflammation associated to hypertension. However, the potential role of APCs in the modulation of renal sodium transport has not been addressed. We hypothesized that APCs participate in renal sodium transport and, thus, development of high blood pressure in response to angiotensin II plus a high-salt diet. Using transgenic mice that allow the ablation of CD11c high APCs, we studied renal sodium tran...
Source
This website uses cookies.
We use cookies to improve your online experience. By continuing to use our website we assume you agree to the placement of these cookies.
To learn more, you can find in our Privacy Policy.