Lei Fang
Wnt signaling pathwaymicroRNACytotoxic T cellApoptosisThyroid cancerPapillary thyroid cancerCancer researchViability assayTransfectionFlow cytometryMAPK/ERK pathwayCell growthProtein kinase BPI3K/AKT/mTOR pathwayBiology
Publications 2
#1Lei FangH-Index: 2
#2Wei XuH-Index: 2
Last. Dedi KongH-Index: 2
view all 3 authors...
Abstract Thyroid cancer (TC) is a familiar cancer, which accounts for approximately 1% of the malignant tumors of all cancers worldwide. Recently, icariin (ICA) has been reported to play an anti-tumor role in different cancers. The study aimed to investigate the effect of ICA on TC cells to uncover the regulatory mechanism. The different concentrations of ICA were stimulated SW579 and TPC1 cells, and cell viability, apoptosis, migration, invasion and main factors of these processes were detected...
16 CitationsSource
#1Lei FangH-Index: 2
#2Dedi KongH-Index: 2
Last. Wei XuH-Index: 2
view all 3 authors...
Abstract Background Thyroid cancer is the most common malignancy in human endocrine system. This study aimed to investigate the effects of microRNA-625-3p (miR-625-3p) on thyroid cancer cell proliferation, migration, invasion and apoptosis, as well as underlying potential mechanism. Methods The relative expressions of miR-625-3p in tumor tissues and adjacent normal tissues of 20 patients with papillary thyroid cancer (PTC) were assessed using qRT-PCR. Cell transfection was used to up-regulate or...
10 CitationsSource