Yangyang Xu
Nanjing University of Chinese Medicine
Therapeutic effectAnalytePharmacodynamicsPharmacokineticsCorrelationTrap (plumbing)Internal medicineBioanalysisMass spectrometryChemistryTraditional Chinese medicineGas chromatography–mass spectrometryMedical prescriptionPrincipal component analysisAminosalicylic acidEnemaMental illnessOral administrationSemenEmodinIrritable bowel syndromeDepression (differential diagnoses)AntidepressantDiarrheaHerbEthyl acetateDrugUlcerative colitisAnthraquinonesPaeoniae RadixClinical treatmentMedicinal herbsChemical basisIntestinal inflammationBupleuri radixChemical markerChemical constituentsDrug formulationsCurative effectHerb pairUhplc q tof msMultivariate statisticalMultivariate analysisEnvironmental scienceElectrospray ionizationChromatographyTraditional medicineSelected reaction monitoringMedicineGastroenterology
8Publications
4H-index
56Citations
Publications 8
Newest
#1Li Xie (Nanjing University of Chinese Medicine)H-Index: 4
#2Xiao Liu (Nanjing University of Chinese Medicine)H-Index: 16
Last. Baochang Cai (Nanjing University of Chinese Medicine)H-Index: 21
view all 11 authors...
Abstract Semen Cassiae, called Juemingzi in Chinese, is widely used in clinic for alleviating constipation, improving eyesight and preventing hyperlipidemia. It can be used as medicine or food including many application forms, such as traditional pieces and ultrafine granular powder (UGP). In this paper, comparative pharmacokinetics of Semen Cassiae in different forms of traditional pieces and UGP were achieved to research the clinical dosage of UGP. Also, the scientific connotation of brewing w...
4 CitationsSource
#1Hao Cai (Nanjing University of Chinese Medicine)H-Index: 21
#2Yangyang Xu (Nanjing University of Chinese Medicine)H-Index: 4
Last. Gang CaoH-Index: 20
view all 11 authors...
Baizhu Shaoyao San (BSS) is a crucial traditional Chinese medicinal formula widely applied for the treatment of painful diarrhea, diarrhea-predominant irritable bowel syndrome, ulcerative colitis, and some other gastrointestinal diseases. Corresponding to the clinical medication, the three medicinal herbs (Atractylodis Macrocephalae Rhizoma, Paeoniae Radix Alba, and Citri Reticulatae Pericarpium) included in BSS should be processed using some specific methods of stir-frying. To find the underlyi...
7 CitationsSource
#1Jia Zhou (Nanjing University of Chinese Medicine)H-Index: 3
#2Hao Cai (Nanjing University of Chinese Medicine)H-Index: 21
Last. Qigang ZhouH-Index: 4
view all 11 authors...
Sinisan has been widely used to treat depression. However, its pharmacologically-effective constituents are largely unknown, and the pharmacological effects and clinical efficacies of Sinisan-containing processed medicinal herbs may change. To address these important issues, we developed an ultra-high performance liquid chromatography coupled with electrospray ionization tandem quadrupole-time-of-flight mass spectrometry (UHPLC-Q-TOF/MS) method coupled with multiple statistical strategies to ana...
9 CitationsSource
#1Yangyang Xu (Nanjing University of Chinese Medicine)H-Index: 4
#2Hao Cai (Nanjing University of Chinese Medicine)H-Index: 21
Last. Lin Shen (Nanjing University of Chinese Medicine)H-Index: 3
view all 11 authors...
To characterize the chemical differences of volatile components between crude and processed Baizhu Shaoyao San (BSS), a classical Chinese herbal formula that is widely applied in the treatment of g...
2 CitationsSource
#1Yangyang XuH-Index: 4
Last. Lin ShenH-Index: 3
view all 11 authors...
Source
#1Yangyang Xu (Nanjing University of Chinese Medicine)H-Index: 4
#2Hao Cai (Nanjing University of Chinese Medicine)H-Index: 21
Last. Lin Shen (Nanjing University of Chinese Medicine)H-Index: 3
view all 13 authors...
Abstract Baizhu Shaoyao San (BSS) is a famous traditional Chinese medicinal formula widely used for the treatment of painful diarrhea, intestinal inflammation, and diarrhea-predominant irritable bowel syndrome. According to clinical medication, three medicinal herbs (Atractylodis Macrocephalae Rhizoma, Paeoniae Radix Alba, and Citri Reticulatae Pericarpium) included in BSS must be processed using some specific methods of stir-frying. On the basis of the classical theories of traditional Chinese ...
28 CitationsSource
#1Jia Zhou (Nanjing University of Chinese Medicine)H-Index: 3
#2Hao Cai (Nanjing University of Chinese Medicine)H-Index: 21
Last. Jing Liu (Nanjing University of Chinese Medicine)H-Index: 3
view all 8 authors...
Depression is a kind of mental illness accompanied by complex etiology and pathogenesis in clinic. With the quickening pace of circadian rhythm and increase of life pressure in modern society, the incidence of depression is increasing year by year. Nowadays, some typical antidepressant Western medicines, such as selective serotonin re-uptake inhibitors (SSRI) and tricyclic antidepressants (TCA), have been used as the main therapeutic drugs in clinic. Unfortunately, administration of these drugs ...
2 CitationsSource
#1Yangyang Xu (Nanjing University of Chinese Medicine)H-Index: 4
#2Hao Cai (Nanjing University of Chinese Medicine)H-Index: 21
Last. Gang Cao (ZJNU: Zhejiang Chinese Medical University)H-Index: 20
view all 7 authors...
Ulcerative colitis is a chronic, nonspecific and complex intestinal disease. The current clinical treatment guideline of this disease recommends a variety of options with oral western medicines, such as aminosalicylic acids, glucocorticosteroids, and immunosuppressors. However, due to their unstable therapeutic effects, high toxicities, and strong drug dependence, they are not suitable for long-term administration. Baizhu Shaoyao powder, a traditional Chinese medicinal prescription, is clinicall...
3 CitationsSource