Javier Labad
Carlos III Health Institute
PsychiatryPsychopathologyInternal medicineEndocrinologyPsychologyCognitionEffects of sleep deprivation on cognitive performanceDelusional disorderProlactinDepression (differential diagnoses)Hypothalamic–pituitary–adrenal axisPsychosisMajor depressive disorderEarly psychosisObsessive compulsiveAnxietyCortisol awakening responseClinical psychologyMedicineSchizophrenia
193Publications
25H-index
2,343Citations
Publications 197
Newest
#1Eloi Giné-ServénH-Index: 1
Last. Javier Labad (Autonomous University of Barcelona)H-Index: 25
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Abstract null null In recent years, multiple studies have investigated the role of biomarkers in first-episode psychosis (FEP) to facilitate early diagnosis, disease stratification, therapeutic choice and outcome prediction. Few studies have focused on cerebrospinal fluid (CSF) investigations. In this prospective observational study, 95 FEP inpatients were followed up for one year. A lumbar puncture was performed at index admission (baseline) to study the CSF parameters (glucose, total proteins,...
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#1Alex Ferrer (University of Barcelona)H-Index: 4
#2Virginia Soria (University of Barcelona)H-Index: 14
Last. Javier Labad (ISCIII: Carlos III Health Institute)H-Index: 25
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Abstract Cognitive impairment has been associated with both childhood adversity and abnormalities of hypothalamic-pituitary-adrenal (HPA) axis function. An interaction exists between the functional polymorphism rs1360780 in the FKBP5 gene and childhood maltreatment, influencing a variety of clinical outcomes. Our goal was to study the relationship between different types of childhood trauma, HPA axis functionality, rs1360780 genotype and cognitive function in 198 healthy individuals who particip...
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Purpose Airway management is a key objective in adapted electroconvulsive therapy (ECT) protocols during the COVID-19 pandemic to prevent infection. The objective of this study was to describe the effectiveness of a modified ventilation procedure designed to reduce aerosol-generating bag-mask ventilation (BMV) and isolate possible droplets while maintaining adequate respiratory gas values in ECT sessions. Materials and Methods This prospective study analyzed the results of the modified protocol ...
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#2Aida ÁlvarezH-Index: 2
Last. Mary V. SeemanH-Index: 50
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The World Health Organization (WHO) developed a 7-year Mental Health Action Plan in 2013, which recommends integration of health and social care services into community-based settings, implementation of strategies for health promotion and prevention of illness, and support of research. In this review, we highlight partial hospitalization programs (PHPs) for delusional disorder (DD), with a special focus on the health and psychosocial needs of women. We suggest that PHPs are, in many ways, ideal ...
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Abstract Background Prolactin (Prl) is a pleiotropic hormone initially described for its regulation of lactation in mammals but later associated with metabolic and immune homeostasis, stress, inflammatory response and human behavior. Its regulation through dopamine receptors highlights its importance in psychiatry mostly because hyperprolactinemia is a common secondary side effect of dopamine antagonists. Despite its undeciphered patho-physiological mechanisms, hyperprolactinemia in naive psycho...
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#1Neus Salvat-PujolH-Index: 6
#2Javier LabadH-Index: 25
Last. Virginia SoriaH-Index: 14
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Relationships among childhood maltreatment (CM), hypothalamic–pituitary–adrenal (HPA) axis disturbances, major depressive disorder (MDD), poor functionality, and lower quality of life (QoL) in adulthood have been described. We aimed to study the roles of the remission status of depression and HPA axis function in the relationships between CM and functionality and QoL. Ninety-seven patients with MDD and 97 healthy controls were included. The cortisol awakening response, cortisol suppression ratio...
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#2Alexandre González-Rodríguez (Autonomous University of Barcelona)H-Index: 13
Last. D.J. Palao Vidal (Autonomous University of Barcelona)H-Index: 1
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Introduction null null null Paranoia querulans is a type of persistent delusional disorder of the persecutory subtype, recognized under ICD-10 and DSM-IV. Being a classically described entity, evidence is lacking from its conceptualization as a nosological entity to diagnosis and treatment. Furthermore, controversy still exists regarding its interplay between the judicial and mental health systems. Objectives null null null To summarize current evidence and knowledge regarding Paranoia querulans...
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#2Alexandre González-Rodríguez (Autonomous University of Barcelona)H-Index: 13
Last. Javier LabadH-Index: 25
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Introduction null null null Mycobacterium kansasii is a nontuberculous mycobacterium that causes infection associated with past or current tuberculosis disease. Clinical syndromes and radiological findings are mostly indistinguishable from that of Mycobacterium tuberculosis, thus requiring microbiological confirmation. Objectives null null null We report a case of a 44-year-old man diagnosed with schizophrenia and Mycobacterium kansasii infection. Methods null null null Case report and non-syste...
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