Alessandra Pelagalli
University of Naples Federico II
Enteroendocrine cellEndocrinologyCellAquaporinReceptorChemistryMesenchymal stem cellImmunologyOrexin-AFibrinogenColostrumGastrointestinal tractLeishmania infantumCancer researchBiochemistryMedicineBlotBiologyPlateletCell biology
58Publications
14H-index
649Citations
Publications 60
Newest
#1Nicola Mirabella (University of Naples Federico II)H-Index: 13
#2Alessandra Pelagalli (University of Naples Federico II)H-Index: 14
Last. Caterina Squillacioti (University of Naples Federico II)H-Index: 13
view all 5 authors...
Abstract Aquaporins (AQPs) are integral transmembrane proteins facilitating transport of water and small solutes, such as glycerol and urea, between cells. In male reproductive tracts, AQPs maintain a milieu conducive for sperm formation, maturation, and storage. The aim of this study was to clarify effects of testicular and epidydimal function on male fertility by investigating localisation and abundances of AQP3 and AQP5 in testes and epididymal segments from dogs with and without unilateral c...
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#1Antonella ZannettiH-Index: 20
#2Gheorghe BengaH-Index: 1
Last. Alessandra PelagalliH-Index: 14
view all 6 authors...
3 CitationsSource
#1Angelica Avagliano (University of Naples Federico II)H-Index: 6
#2Giuseppe FiumeH-Index: 16
Last. Alessandro Arcucci (University of Naples Federico II)H-Index: 11
view all 7 authors...
Cutaneous melanoma (CM) is a highly aggressive and drug resistant solid tumour, showing an impressive metabolic plasticity modulated by oncogenic activation. In particular, melanoma cells can generate adenosine triphosphate (ATP) during cancer progression by both cytosolic and mitochondrial compartments, although CM energetic request mainly relies on glycolysis. The upregulation of glycolysis is associated with constitutive activation of BRAF/MAPK signalling sustained by BRAFV600E kinase mutant....
15 CitationsSource
#1Barbara Lamagna (University of Naples Federico II)H-Index: 6
#2Paolo Ciaramella (University of Naples Federico II)H-Index: 15
Last. Alessandra Pelagalli (University of Naples Federico II)H-Index: 14
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Aquaporins (AQPs) are a family of thirteen membrane proteins that play an essential role in the transport of fluids across the cell plasma membrane. Recently, the expression of AQPs in different ocular tissues and their involvement in the pathophysiology of eye diseases, have garnered attention. Considering that literature on AQP expression in the lacrimal glands and their secretion is scarce, we aimed to characterise AQP1 expression in the tears of healthy dogs using two tear collection methods...
2 CitationsSource
#2Nadia MuscoH-Index: 8
Last. Serena CalabròH-Index: 17
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Faba bean is an important vegetable protein source for ruminant diets. This research aimed to compare the nutritional characteristics of four commercial and four local cultivars in order to better characterise the local ones and promote their use in animal nutrition. The seeds’ weight and the chemical composition, including starch and the energy, was evaluated. The in vitro fermentation characteristics were studied for 48 h using bull’s rumen fluid as inoculum. All the varieties showed the value...
1 CitationsSource
#1Laura Cortese (University of Naples Federico II)H-Index: 15
#2Pete W. Christopherson (AU: Auburn University)H-Index: 8
Last. Alessandra Pelagalli (University of Naples Federico II)H-Index: 14
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Significant progress has been made in the functional characterization of canine platelets in the last two decades. The role of canine platelets in hemostasis includes their adhesion to the subendothelium, activation, and aggregation, leading to primary clot formation at the site of injury. Studies on canine platelet function and advancements in laboratory testing have improved the diagnosis and understanding of platelet-related disorders as well as the knowledge of the mechanisms behind these di...
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#1Loredana Assisi (University of Naples Federico II)H-Index: 14
#2Alessandra Pelagalli (University of Naples Federico II)H-Index: 14
Last. Nicola Mirabella (University of Naples Federico II)H-Index: 13
view all 6 authors...
Orexin A (OxA) is a neuropeptide produced in the lateral hypothalamus that performs pleiotropic functions in different tissues, including involvement in energy homeostasis and reproductive neuroendocrine functions. The role of OxA is particularly important given the well-studied relationships between physiological mechanisms controlling energy balance and reproduction. The enzyme P450 aromatase (ARO) helps convert androgens to estrogens and has roles in steroidogenesis, spermatogenesis, and ener...
1 CitationsSource
#1Heba Abdelrazik (Cairo University)H-Index: 2
#2Emanuele Giordano (UNIBO: University of Bologna)H-Index: 22
Last. Alessandra Pelagalli (University of Naples Federico II)H-Index: 14
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Mesenchymal stem cells (MSC) have piqued worldwide interest for their extensive potential to treat a large array of clinical indications, their unique and controversial immunogenic and immune modulatory properties allowing ample discussions and debates for their possible applications. Emerging data demonstrating that the interaction of biomaterials and physical cues with MSC can guide their differentiation into specific cell lineages also provide new interesting insights for further MSC manipula...
9 CitationsSource
#1Caterina Squillacioti (University of Naples Federico II)H-Index: 13
#2Alessandra Pelagalli (University of Naples Federico II)H-Index: 14
Last. Nicola Mirabella (University of Naples Federico II)H-Index: 13
view all 4 authors...
Urocortins (Ucns), peptides belonging to the corticotropin-releasing hormone (CRH) family, are classified into Ucn1, Ucn2, and Ucn3. They are involved in regulating several body functions by binding to two G protein-coupled receptors: receptor type 1 (CRHR1) and type 2 (CRHR2). In this review, we provide a historical overview of research on Ucns and their receptors in the mammalian endocrine system. Although the literature on the topic is limited, we focused our attention particularly on the mai...
1 CitationsSource
#1Caterina Squillacioti (University of Naples Federico II)H-Index: 13
#2Alessandra Pelagalli (University of Naples Federico II)H-Index: 14
Last. Nicola Mirabella (University of Naples Federico II)H-Index: 13
view all 6 authors...
: Cryptorchidism is associated with changes in the gonads and the spermatic duct system, which may cause infertility problems. Urocortin (UCN) is a corticotrophin-releasing hormone (CRH)-related peptide, which affects several functions of male genital organs. The aim of the present study was to investigate the expression of UCN and its receptors CRHR1 and CRHR2 using immunohistochemistry, western blotting and real-time reverse transcription polymerase chain reaction in tissues collected from the...
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