Cristiane Grella Miranda
Federal University of Technology - Paraná
Nuclear chemistryAbsorption (skin)NanoparticleNutraceuticalOrganic chemistryEnzymeBioavailabilityAqueous solutionChemistryIn vitroMyeloperoxidaseIn vivoCompatibilizationCurcuminoidCurcuminLuteinAcetylcholinesterasePolyvinylpyrrolidoneAqueous mediumIndustrial utilizationIn silico dockingHydrophilic matrixNutritional compositionMic valuesFood scienceIn vitro toxicologyBiochemistry
Publications 4
#1Cristiane Grella Miranda (UTFPR: Federal University of Technology - Paraná)H-Index: 3
#2Priscila Dayane Freitas dos Santos (UTFPR: Federal University of Technology - Paraná)H-Index: 2
Last. Odinei Hess Gonçalves (IPN: Instituto Politécnico Nacional)H-Index: 16
view all 8 authors...
Abstract Lutein is a bioactive found in dark leafy vegetables that may be used as a nutraceutical agent in foodstuff and an inhibitor of key enzymes of the human body such as those involved in the cholinergic system. However, its high hydrophobicity leads to low bioavailability and must be overcome if lutein is to be added in foods. The objective of this study was to evaluate the influence of nanoencapsulated lutein in the activity of the acetylcholinesterase enzyme. The in vitro study was carri...
5 CitationsSource
#1Heloísa H.S. Almeida (UTFPR: Federal University of Technology - Paraná)H-Index: 1
#2Lillian Barros (IPN: Instituto Politécnico Nacional)H-Index: 78
Last. Isabel C.F.R. Ferreira (IPN: Instituto Politécnico Nacional)H-Index: 97
view all 10 authors...
Abstract Curcumin (E100) is a natural colorant that, besides conferring color, has bioactivity, serving as an alternative to some artificial colorants. As a hydrophobic colorant, its modification/compatibilization with the aqueous medium is required to improve stability and enable its application in hydrophilic food matrices. Herein, different formulations of curcumin (curcumin powder: PC, water-dispersible curcumin: DC: and nanoencapsulated curcumin: NC) were evaluated as yogurt colorants. PC s...
13 CitationsSource
Curcumin is the main curcuminoid found in turmeric rhizomes and is a strong candidate to formulate foodstuff with specific properties. Among various bioactive properties of curcumin, its antiinflammatory activity is remarkable; on the other hand, its low water solubility leads to low absorption. Thus, new formulations need to be developed to improve its efficacy, and encapsulation is a promising alternative strategy in this regard. The objective of the present study was to obtain curcumin-loaded...
27 CitationsSource
OBJETIVO: A curcumina e um composto com varias caracteristicas interessantes para uso nas areas farmaceuticas e alimenticias, todavia, sua instabilidade frente a condicoes externas e insolubilidade em agua diminuem sua aplicabilidade. Deste modo, tecnicas vem sendo estudas para melhorar as caracteristicas tecnologicas da curcumina como a nanoencapsulacao, que vem se mostrando uma alterativa promissora para aumentar a sua biodisponibilidade. O objetivo do trabalho foi encapsular a curcumina utili...