Marziyeh Salehiabar
Tabriz University of Medical Sciences
CytotoxicitySurface modificationAnalytical chemistryNuclear chemistryNanoparticleFourier transform infrared spectroscopyControlled releaseNanotechnologyInorganic chemistryNanocarriersChemistryMaterials scienceAlbuminChemotherapyBiocompatibilityIron oxideCurcuminMRI contrast agentChrysinDrug deliveryHemolysisMTT assaySurface coating2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Differential scanning calorimetryComputer scienceBiomoleculeThermogravimetric analysisMedicineBovine serum albuminMagnetic nanoparticlesCRISPRPharmacology
19Publications
10H-index
386Citations
Publications 18
Newest
#1Hamid Rashidzadeh (Zanjan University of Medical Sciences)H-Index: 5
#2Hossein Danafar (Zanjan University of Medical Sciences)H-Index: 30
Last. Mehdi Mirsaeidi (UM: University of Miami)H-Index: 32
view all 19 authors...
Coronavirus 2019 (COVID-19), as an emerging infectious disease, has caused significant mortality and morbidity along with socioeconomic impact. No effective treatment or vaccine has been approved yet for this pandemic disease. Cutting-edge tools, especially nanotechnology, should be strongly considered to tackle this virus. This review aims to propose several strategies to design and fabricate effective diagnostic and therapeutic agents against COVID-19 by the aid of nanotechnology. Polymeric, i...
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#1Hossein Rahimi (Zanjan University of Medical Sciences)H-Index: 2
#2Marziyeh Salehiabar (Tabriz University of Medical Sciences)H-Index: 10
Last. João Conde (NOVA: Universidade Nova de Lisboa)H-Index: 33
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The emergence of the new coronavirus 2019 (COVID-19) was first seen in December 2019, which has spread rapidly and become a global pandemic. The number of cases of COVID-19 and its associated mortality have raised serious concerns worldwide. Early diagnosis of viral infection undoubtedly allows rapid intervention, disease management, and substantial control of the rapid spread of the disease. Currently, the standard approach for COVID-19 diagnosis globally is the RT-qPCR test; however, the limit...
5 CitationsSource
#1Hossein Rahimi (Zanjan University of Medical Sciences)H-Index: 2
#2Marziyeh Salehiabar (Tabriz University of Medical Sciences)H-Index: 10
Last. Thomas J. Webster (NU: Northeastern University)H-Index: 104
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Abstract Exploiting bacterial DNA-acting enzymes and expanding their repertoire for genome engineering have been major technological and conceptual advances in molecular biology over the last decade. The CRISPR-Cas9 system offers many attractive superiorities, such as multiplexing, high precision, low cost, and simplicity compared to other strategies/systems/approaches known to date for gene editing. The efficient co-delivery of Cas9 and single guide RNA(s) into a desired cell and subsequent cor...
7 CitationsSource
#1Hamed NosratiH-Index: 19
#2Akram RakhshbaharH-Index: 2
Last. Soodabeh DavaranH-Index: 40
view all 7 authors...
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#1Hossein Rahimi (Zanjan University of Medical Sciences)H-Index: 2
#2Marziyeh Salehiabar (Tabriz University of Medical Sciences)H-Index: 10
Last. Hamed Nosrati (Zanjan University of Medical Sciences)H-Index: 19
view all 5 authors...
Proteins have been used to fabricate and design carriers for systemic drug delivery. One of the proteins that shows great potential for the applications in systemic delivery is albumin which is the most abundant plasma protein. This protein has been widely used in nanotechnology-based treatments of many diseases as a promising drug carrier. Taking cancer, an age-associated disease, as an example, the use of albumin nanoparticles as a drug carrier overcomes some of the limitations of chemotherapy...
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#1Hamed Nosrati (Zanjan University of Medical Sciences)H-Index: 19
#2Marziyeh Salehiabar (Tabriz University of Medical Sciences)H-Index: 10
Last. Hossein Danafar (Zanjan University of Medical Sciences)H-Index: 30
view all 6 authors...
At this time, passive targeting with the aid of enhanced permeability and retention (EPR effect), active targeting with the aid of molecular or other targeting agents, and employing external magnetic field are used to successfully deliver IONPs to aim tumor site. Latest progresses in treatment of disease are toward targeted delivery. With fast progresses in this field, researchers employed the IONPs as a hopeful theranostic vehicle. In this chapter, we focused on passive and active target delive...
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#1Hamed Nosrati (Zanjan University of Medical Sciences)H-Index: 19
#2Jalil Charmi (ZNU: University of Zanjan)H-Index: 6
Last. Hossein Danafar (Zanjan University of Medical Sciences)H-Index: 30
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Combination therapy such as radiotherapy combined with chemotherapy has attracted excessive interest in the new cancer research area. Therefore, developing nanobiomaterials for combination of radiotherapy and chemotherapy is required for more powerful and successful cures. Because of the amazing X-ray sensitization proficiency of Bi based nanoparticles, in this work, we synthesized and used Bi2S3 as an enhancer of X-ray radiation therapy, and furthermore, Bi2S3 served as carrier of curcumin (CUR...
13 CitationsSource
#1Hamed Nosrati (Zanjan University of Medical Sciences)H-Index: 19
#2Marziyeh Salehiabar (Tabriz University of Medical Sciences)H-Index: 10
Last. Hossein Danafar (Zanjan University of Medical Sciences)H-Index: 30
view all 7 authors...
Iron oxide magnetic nanoparticles (IONPs) have attracted enormous attention because of their extensive medicinal and industrial applicability. PEGylated L-arginine modified iron oxide magnetic nanoparticles (PEG-Arg@IONPs) were synthesized and functioned in the present research as MRI contrast agents considered in vivo BALB/c model. The Synthesized PEG-Arg@IONPs were tracked in certain time intervals by MRI. The intensity of MR imaging of kidneys increased after administration of PEG-Arg@IONPs, ...
13 CitationsSource
#1Hamed Nosrati (Zanjan University of Medical Sciences)H-Index: 19
#2Akram Rakhshbahar (Zanjan University of Medical Sciences)H-Index: 2
Last. Soodabeh Davaran (Tabriz University of Medical Sciences)H-Index: 40
view all 7 authors...
Abstract This study manipulated a chrysin loaded bovine serum albumin nanoparticles (BSA NPs), which could solubilize the poorly water-soluble drug and increase the therapeutic efficacy of the drug. Chrysin (5, 7-dihydroxyflavone) is a natural flavonoid which have some significant biological effects on the processes of chemical defense. Chrysin loaded bovine serum albumin nanoparticles (Chrysin-BSA NPs) were synthesized by a simple desolvation procedure. The resultant Chrysin-BSA NPs showed a sp...
15 CitationsSource
#1Hamed Nosrati (Zanjan University of Medical Sciences)H-Index: 19
#2Marziyeh Salehiabar (Zanjan University of Medical Sciences)H-Index: 10
Last. Hossein Danafar (Zanjan University of Medical Sciences)H-Index: 30
view all 6 authors...
AbstractThis study is a report about the synthesis iron oxide magnetic nanoparticles (IONPs) which modified with positive and negative charged amino acids (AAs). l-Arginine (Arg) and l-aspartic acid (Asp) which have of guanidinium and carboxylic acid groups, respectively, were selected for this study. After loading chrysin in amino acids modified iron oxide magnetic nanoparticles (F@AAs@Chrysin NPs), it was characterized by XRD, TGA, FTIR, VSM, and TEM techniques. Finally, MTT assays on HFF-2 an...
5 CitationsSource