Paolo Zunino

Polytechnic University of Milan

Porous mediumBiot numberPhysicsMathematical optimizationMicrocirculationMathematical analysisFinite element methodBiomedical engineeringPoromechanicsMaterials scienceApplied mathematicsDrug releaseMathematicsFlow (mathematics)Computer scienceComputer simulationMechanicsMedicineDiscretizationPartial differential equation

151Publications

28H-index

1,970Citations

Publications 148

#1M. Caputo (Polytechnic University of Milan)H-Index: 1

#2Claudio Chiastra (Polytechnic University of Milan)H-Index: 18

Last. Paolo Zunino (Polytechnic University of Milan)H-Index: 28

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SUMMARY Computational models are used to study the combined effect of biomechanical and biochemical factors on coronary in-stent restenosis, which is a postoperative remodeling and regrowth pathology of the stented arteries. More precisely, we address numerical simulations, on the basis of Navier–Stokes and mass transport equations, to study the role of perturbed wall shear stresses and reduced oxygen concentration in a geometrical model reconstructed from a real porcine artery treated with a st...

#1Sandro SalsaH-Index: 24

#2Federico M. G. VegniH-Index: 2

Last. Paolo ZuninoH-Index: 28

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Introduction.- Scalar Conservation Laws.- Diffusion.- The Laplace Equation.- Reaction-diffusion models.- Waves and vibrations.- Elements of Functional Analysis.- Variational formulation of elliptic problems.- Weak formulation of evolution problems.- Solutions.- Fourier Series.- Notes on ordinary differential equations.- Finite difference approximation of time dependent problems.- Identities and Formulas.

#1Giusy MazzoneH-Index: 5

#2Giovanni P. GaldiH-Index: 39

Last. Paolo ZuninoH-Index: 28

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#1Rana ZakerzadehH-Index: 6

#2Paolo ZuninoH-Index: 28

Last. Ivan YotovH-Index: 33

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#1Paolo ZuninoH-Index: 28

#2Laura CattaneoH-Index: 13

Modeling blood flow as a fluid- multilayered structure interaction problem consisting of poroelastic materials

#1Martina BukacH-Index: 11

#2Paolo ZuninoH-Index: 28

Last. Ivan YotovH-Index: 33

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#1Giovanni P. GaldiH-Index: 39

#2Giusy MazzoneH-Index: 5

Last. Paolo ZuninoH-Index: 28

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#1Giovanni P. Galdi (University of Pittsburgh)H-Index: 39

#2Giusy Mazzone (University of Pittsburgh)H-Index: 5

Last. Paolo Zunino (University of Pittsburgh)H-Index: 28

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We study inertial motions of the coupled system, \({\mathscr{S}}\), constituted by a rigid body containing a cavity entirely filled with a viscous liquid. We show that for arbitrary initial data having only finite kinetic energy, every corresponding weak solution (a la Leray–Hopf) converges, as time goes to infinity, to a uniform rotation, unless two central moments of inertia of \({\mathscr{S}}\) coincide and are strictly greater than the third one. This corroborates a famous “conjecture” of N....

Explicit partitioning strategies for the interaction between a fluid and a multilayered poroelastic structure: an operator-splitting approach

#1Martina BukacH-Index: 11

#2Paolo ZuninoH-Index: 28

Last. Ivan YotovH-Index: 33

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We study the interaction between an incompressible, viscous, Newtonian fluid and a multilayered structure, which consists of a thin elastic layer and a thick poroelastic material. The thin layer is modeled using the linearly elastic Koiter membrane model, while the thick poroelastic layer is modeled as a Biot system. The objective of this work is to investigate how the poroelastic phenomena affect the characteristic features of blood flow in arteries, such as propagation of pressure waves. We de...

Drug delivery patterns for different stenting techniques in coronary bifurcations: a comparative computational study.

#1Elena Cutrì (Polytechnic University of Milan)H-Index: 7

#2Paolo Zunino (University of Pittsburgh)H-Index: 28

Last. Francesco Migliavacca (Polytechnic University of Milan)H-Index: 60

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The treatment of coronary bifurcation lesions represents a challenge for the interventional cardiologists due to the lower rate of procedural success and the higher risk of restenosis. The advent of drug-eluting stents (DES) has dramatically reduced restenosis and consequently the request for re-intervention. The aim of the present work is to provide further insight about the effectiveness of DES by means of a computational study that combines virtual stent implantation, fluid dynamics and drug ...

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