Saqib Mumtaz
St James's University Hospital
Internal medicineSurgeryImmunologySeHCATCholecystectomyInflammatory bowel diseaseIrritable bowel syndromeCalprotectinMicroscopic colitisFaecal calprotectinDepression (differential diagnoses)DiseaseComorbidityCrohn's diseaseBile acidDiarrheaUlcerative colitisPopulationChronic diarrheaMucosal inflammationClinical diseaseIn patientAnxietyMedicineGastroenterology
15Publications
6H-index
251Citations
Publications 14
Newest
#1Shujing Jane Lim (St James's University Hospital)H-Index: 1
#2David J. Gracie (University of Leeds)H-Index: 16
Last. Christopher J Black (University of Leeds)H-Index: 13
view all 8 authors...
BACKGROUND: 23-seleno-25-homo-tauro-cholic acid (SeHCAT) scanning to rule out bile acid diarrhea (BAD) in patients with chronic diarrhea has a high yield. Our previous study showed that patients with terminal ileal (TI) Crohn's disease, TI resection, or cholecystectomy were highly likely to have an abnormal scan. As a result, we encouraged clinicians to use a therapeutic trial of a bile acid sequestrant in these patients, instead of scanning. This may have reduced diagnostic yield of the test, s...
5 CitationsSource
#1Y. Derwa (University of Leeds)H-Index: 4
#2Christopher J.M. Williams (University of Leeds)H-Index: 4
Last. David J. Gracie (University of Leeds)H-Index: 16
view all 9 authors...
Objectives: Patient-reported symptoms correlate poorly with mucosal inflammation. Clinical decision-making may, therefore, not be based on objective evidence of disease activity. We conducted a study to determine factors associated with clinical decision-making in a secondary care inflammatory bowel disease (IBD) population, using a cross-sectional design. Methods: Decisions to request investigations or escalate medical therapy were recorded from outpatient clinic encounters in a cohort of 276 p...
10 CitationsSource
#1David J. GracieH-Index: 16
Last. Alexander C. FordH-Index: 86
view all 7 authors...
#1David J. Gracie (University of Leeds)H-Index: 16
#2Christopher J.M. Williams (St James's University Hospital)H-Index: 4
Last. Alexander C. Ford (University of Leeds)H-Index: 86
view all 7 authors...
Background & Aims Symptoms compatible with irritable bowel syndrome (IBS) are common in patients with inflammatory bowel disease (IBD), but it is unclear whether this relates to occult IBD activity. We attempted to resolve this issue in a secondary care population by using a cross-sectional study design. Methods We analyzed Rome III IBS symptoms, disease activity indices, and psychological, somatization, and quality of life data from 378 consecutive, unselected adult patients with IBD seen in cl...
40 CitationsSource
#1Y. Derwa (St James's University Hospital)H-Index: 4
#2David J. Gracie (University of Leeds)H-Index: 16
Last. Alexander C. Ford (University of Leeds)H-Index: 86
view all 8 authors...
Source
#1David J. Gracie (St James's University Hospital)H-Index: 16
#2Christopher J.M. Williams (St James's University Hospital)H-Index: 4
Last. Alexander C. Ford (St James's University Hospital)H-Index: 86
view all 7 authors...
Poor Correlation Between Clinical Disease Activity and Mucosal Inflammation, and the Role of Psychological Comorbidity, in Inflammatory Bowel Disease
61 CitationsSource
#1Imran Aziz (Royal Hallamshire Hospital)H-Index: 21
#2Saqib Mumtaz (St James's University Hospital)H-Index: 6
Last. Alexander C. Ford (University of Leeds)H-Index: 86
view all 6 authors...
Background & Aims Some studies have found that patients with idiopathic bile acid diarrhea (BAD) present with symptoms of diarrhea-predominant irritable bowel syndrome (D-IBS). However, these studies either were retrospective, did not define D-IBS according to current criteria, or included patients with chronic functional diarrhea. We performed a prospective study of the prevalence of idiopathic BAD in consecutive patients fulfilling the Rome III criteria for D-IBS. Methods We analyzed data from...
46 CitationsSource
#1David J. Gracie (University of Leeds)H-Index: 16
#2Christopher J.M. Williams (St James's University Hospital)H-Index: 4
Last. Alexander C. Ford (University of Leeds)H-Index: 86
view all 7 authors...
Introduction The Harvey-Bradshaw index (HBI) and simple clinical colitis activity index (SCCAI) are clinical scoring systems used to estimate Crohn’s disease (CD), and ulcerative colitis (UC) activity, respectively. However, whether they are superior to the patient’s own opinion at predicting disease activity, defined by faecal biomarkers of inflammatory bowel disease (IBD) activity is unclear. We conducted a cross-sectional survey of IBD patients to assess these issues. Method Patient opinion a...
Source
#1David J. Gracie (University of Leeds)H-Index: 16
#2Christopher J.M. Williams (St James's University Hospital)H-Index: 4
Last. Alexander C. Ford (University of Leeds)H-Index: 86
view all 7 authors...
Introduction The prevalence of symptoms compatible with irritable bowel syndrome (IBS) in inflammatory bowel disease (IBD) has been previously described.1However, the association between the presence of these symptoms and occult disease activity is less well known, as is the effect of these symptoms on psychological health. We conducted a cross-sectional survey examining these issues. Method Demographic and gastrointestinal symptom data were collected from 439 adult patients via the Rome III que...
Source
#1Victoria WarrenH-Index: 1
#2Amer F. RehmanH-Index: 1
Last. Christian P. SelingerH-Index: 25
view all 9 authors...
Source