Rong Yan
Guangzhou University
Internal medicineSynapseEndocrinologyLipofuscinImmunologyAutophagyLong-term potentiationSuperoxide dismutaseHippocampusSignal transductionBiologyGap-43 protein
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#1Yunbo Chen (GU: Guangzhou University)H-Index: 3
#2Gang Wei (GU: Guangzhou University)H-Index: 3
Last. Dongfeng Chen (GU: Guangzhou University)H-Index: 22
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Abstract β-Asarone is an active component of the Acori graminei rhizome that is a traditional Chinese medicine clinically used in treating dementia in China. However, the cognitive effect of β-asarone and its mechanism has remained elusive. Here, we used asenescence-accelerated prone 8 (SAMP8) mice, which mimic many of the salient features of Alzheimer׳s disease (AD), to further investigate whether modulation of the ROCK signaling pathway and/or autophagy, synaptic loss is involved in the effect...
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