Xiumin Tian
Shenyang Pharmaceutical University
BioassayAnalytical chemistryIonMass spectrometryFourier transform ion cyclotron resonanceHigh-performance liquid chromatographyChemistryDecoctionDemethylationRadixMetabolomicsMaximAcetonitrilePalmitoylcarnitineFatty acid amideGlucuronideOleamideUrineHydroxylationGegenqinlianActive componentsChromatographyFatty acidBiochemistryMetabolismBeta oxidationCatabolism
5Publications
3H-index
28Citations
Publications 5
Newest
#1Xiumin TianH-Index: 3
#2Xiuying YanH-Index: 2
view all 7 authors...
#1Ting Liu (SPU: Shenyang Pharmaceutical University)H-Index: 6
#2Xiumin Tian (SPU: Shenyang Pharmaceutical University)H-Index: 3
Last. Zhiguo Yu (SPU: Shenyang Pharmaceutical University)H-Index: 16
view all 7 authors...
Abstract Gegenqinlian decoction (GQLD) as a traditional Chinese medical (TCM) prescription is made from four Chinese herbs and has been used for centuries to treat pyrexia and diarrhea. In this work, an ultra-high performance liquid chromatography coupled with Fourier transform ion cyclotron resonance mass spectrometry (UHPLC-FT-ICR-MS) method was established to profile the metabolic fate of GQLD in rat plasma, urine, bile and feces. The analysis was performed on a Waters Acquity UPLC HSS T3 col...
17 CitationsSource
#1Ting Liu (SPU: Shenyang Pharmaceutical University)H-Index: 6
#2Yue Cui (SPU: Shenyang Pharmaceutical University)H-Index: 2
Last. Zhiguo Yu (SPU: Shenyang Pharmaceutical University)H-Index: 16
view all 8 authors...
Gegenqinlian decoction (GQLD) is one of the classic traditional Chinese medicines. The formula consists of four herbal medicines including Radix Puerariae lobatae, Radix Scutellariae, Coptidis Rhizoma, and Glycyrrhizae Radix et Rhizoma Praeparata Cum Melle. In this study, an ultra-high performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry method was employed to investigate the major constituents in GQLD. Liquid chromatographic separation was ...
8 CitationsSource
#1Ting Liu (SPU: Shenyang Pharmaceutical University)H-Index: 6
#2Songhe Li (SPU: Shenyang Pharmaceutical University)H-Index: 2
Last. Zhiguo Yu (SPU: Shenyang Pharmaceutical University)H-Index: 16
view all 8 authors...
Abstract Pyrexia usually is a systemic pathological process that can lead to metabolic disorders. Metabonomics as a powerful tool not only can reveal the pathological mechanisms, but also can give insight into the progression of pyrexia from another angle. Thus, an ultra high performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry (UHPLC-FT-ICR-MS) metabonomic approach was employed for the first time to investigate the plasma biochemical charac...
7 CitationsSource
#1Ting LiuH-Index: 6
#2Songhe LiH-Index: 2
Last. Zhiguo Yu
view all 8 authors...
Pyrexia usually is a systemic pathological process that can lead to metabolic disorders. Metabonomics as a powerful tool not only can reveal the pathological mechanisms, but also can give insight into the progression of pyrexia from another angle. Thus, an ultra high performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry (UHPLC-FT-ICR-MS) metabonomic approach was employed for the first time to investigate the plasma biochemical characteristics...