Sanjay Kumar
Mayo Clinic
Surface roughnessPhase (waves)PhysicsGeologyPetroleum cokeCeramicMathematical analysisBilayer grapheneUnits of measurementAngle-resolved photoemission spectroscopyNonlinear systemComposite materialQuadrature (mathematics)SeismologyPhasorTight bindingBilayerMaterials scienceReliability engineeringCondensed matter physicsInvestment castingShell (structure)GrapheneMathematicsObservabilityFermi levelComputer scienceOrdinary differential equationDensity of statesBasis functionControl theoryPorosityElectric power systemCoulombSlurryRadial basis function
64Publications
15H-index
541Citations
Publications 23
Newest
#2Stanislav V. Yuzhakov (Mayo Clinic)H-Index: 1
Last. John C. LieskeH-Index: 66
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#1Bhaskar Illa (NGRI: National Geophysical Research Institute)
#2K.S. Reshma (NGRI: National Geophysical Research Institute)
Last. Prantik Mandal (NGRI: National Geophysical Research Institute)H-Index: 25
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Abstract High-resolution P-wave velocity and anisotropy structure of the hitherto elusive uppermost mantle beneath the Indian shield and its surrounding regions are presented to unravel the tectonic imprints in the lithosphere. We inverted high quality 19,500 regional Pn phases from 172 seismological stations for 4780 earthquakes at a distance range of 2° to 15° with a mean apparent Pn velocity of 8.22 km/s. The Pn velocity anomalies with fast anisotropic directions are consistent with the colli...
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#1M.F. Nagoor Meeran (United Arab Emirates University)H-Index: 4
#2Sheikh Azimullah (United Arab Emirates University)H-Index: 17
Last. Shreesh Ojha (United Arab Emirates University)H-Index: 30
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The clinical usage of doxorubicin (DOX), a potent anthracycline antineoplastic drug, is limited due to its cardiotoxicity. The aim of this study was to assess the possible cardioprotective effects of nerolidol (NERO) in a rat model of DOX-induced chronic cardiotoxicity and the underlying molecular mechanisms. DOX (2.5 mg/kg) was injected intraperitoneally once in a week for 5 weeks to induce chronic cardiotoxicity in male albino Wistar rats. The rats were treated with NERO (50 mg/kg, orally) 6 d...
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#1Jiqing Zhang (Capital Medical University)
#2Sanjay Kumar (Mayo Clinic)H-Index: 15
Last. John C. Lieske (Mayo Clinic)H-Index: 66
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BACKGROUNDS Previous studies have demonstrated that excretion of urinary extracellular vesicles (EVs) from different nephron segments differs between kidney stone formers and non-stone formers (NSFs), and could reflect pathogenic mechanisms of urinary stone disease. In this study we quantified selected populations of specific urinary EVs carrying protein markers of immune cells and calcium/phosphorus physiology in calcium oxalate stone formers (CSFs) compared to non-stone formers (NSFs). METHODS...
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#1M.F. Nagoor Meeran (United Arab Emirates University)H-Index: 4
#2Hayate Javed (United Arab Emirates University)H-Index: 25
Last. Shreesh Ojha (United Arab Emirates University)H-Index: 7
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Abstract Coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an ongoing public health emergency. The pathogenesis and complications advanced with infection mainly involve immune-inflammatory cascade. Therefore, the therapeutic strategy relies on immune modulation, reducing infectivity and inflammation. Given the interplay of infection and immune-inflammatory axis, the natural products received attention for preventive and therap...
1 CitationsSource
#1M.F. Nagoor Meeran (United Arab Emirates University)H-Index: 4
#2Charu Sharma (United Arab Emirates University)H-Index: 11
Last. Shreesh Ojha (United Arab Emirates University)H-Index: 30
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The COVID-19 pandemic caused by SARS-CoV-2 is a deadly disease afflicting millions. The pandemic continues affecting population due to nonavailability of drugs and vaccines. The pathogenesis and complications of infection mainly involve hyperimmune-inflammatory responses. Thus, therapeutic strategies rely on repurposing of drugs aimed at reducing infectivity and inflammation and modulate immunity favourably. Among, numerous therapeutic targets, the endocannabinoid system, particularly activation...
1 CitationsSource
#1Muthuvel Jayachandran (Mayo Clinic)H-Index: 30
#2Stanislav V. Yuzhakov (Mayo Clinic)H-Index: 1
Last. John C. Lieske (Mayo Clinic)H-Index: 66
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BACKGROUND Primary hyperoxaluria type 1 (PH1) is associated with nephrocalcinosis (NC) and calcium oxalate (CaOx) kidney stones (KS). Populations of urinary extracellular vesicles (EVs) can reflect kidney pathology. The aim of this study was to determine whether urinary EVs carrying specific biomarkers and proteins differ among PH1 patients with NC, KS or with neither disease process. METHODS Mayo Clinic Rare Kidney Stone Consortium bio-banked cell-free urine from male and female PH1 patients wi...
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#1Anatilde M. Gonzalez Guerrico (Mayo Clinic)H-Index: 3
#2John C. Lieske (Mayo Clinic)H-Index: 66
Last. Marie C. Hogan (Mayo Clinic)H-Index: 37
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Abstract Introduction Heterogeneity of nephrotic diseases and a lack of validated biomarkers limits interventions and reduces ability to examine outcomes. Urinary CD80 is a potential biomarker for minimal change disease (MCD) steroid sensitive nephrotic syndrome (NS). We investigated and validated a CD80 ELISA assay in urine in a large cohort with a variety of nephrotic diseases Methods A commercial CD80 ELISA assay was enhanced and analytically validated for urine. Urine from Mayo (286) and NEP...
3 CitationsSource
#1Vijay Ramakrishnan (Mayo Clinic)H-Index: 11
#2Kevin C. Miller (Mayo Clinic)H-Index: 5
Last. Shaji Kumar (Mayo Clinic)H-Index: 123
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Despite recent advances, patients with multiple myeloma still inevitably relapse and become refractory to existing therapies. Mutations in K-RAS, N-RAS and B-RAF are common in multiple myeloma, affecting 50% of patients at diagnosis and >70% at relapse. However, targeting mutated RAS/RAF via MEK inhibition is merely cytostatic in myeloma and largely ineffective in the clinic. We examined mechanisms mediating this resistance and identified histone deacetylase (HDAC) inhibitors as a potent synergi...
10 CitationsSource
#1Sanjay Kumar (Mayo Clinic)H-Index: 15
#1Sanjay Kumar (Mayo Clinic)H-Index: 7
Last. Angela DispenzieriH-Index: 138
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