Phil A. Hart
The Ohio State University Wexner Medical Center
CancerInternal medicineRadiologySurgeryPathologyOncologyIntensive care medicinePancreatitisAcute pancreatitisAutoimmune pancreatitisPancreasDiseasePancreatic cancerEndoscopic ultrasoundConfocal laser endomicroscopyNuclear medicineIn patientCystic lesionDiabetes mellitusGeneral surgeryMedicineGastroenterology
Publications 183
#1Dana K. AndersenH-Index: 21
#2Suresh T. ChariH-Index: 103
Last. Stephen J. PandolH-Index: 74
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#1Brandon K. Chu (The Ohio State University Wexner Medical Center)
#2Bipul Gnyawali (OSU: Ohio State University)
Last. Somashekar G. Krishna (The Ohio State University Wexner Medical Center)H-Index: 21
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BACKGROUND Same-admission cholecystectomy (CCY) is recommended for mild acute biliary pancreatitis (biliary-AP). However, there is a paucity of research investigating reasons for early (30-day) unplanned readmissions in patients who undergo CCY for biliary-AP. Hence, we sought to investigate this gap using a large population database. METHODS Using the Nationwide Readmission Database (2010-2014), we identified all adults (age ≥ 18 years) with a principal diagnosis of biliary-AP who had undergone...
#1Phil A. Hart (The Ohio State University Wexner Medical Center)H-Index: 29
#2David Bradley (The Ohio State University Wexner Medical Center)H-Index: 15
Last. Jose Serrano (NIH: National Institutes of Health)H-Index: 49
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Summary null null Diabetes represents a group of diseases involving persistent hyperglycaemia. Exocrine disorders of the pancreas are increasingly recognised to cause or precede the onset of diabetes, which in this context is referred to as pancreatogenic or type 3c diabetes. Diabetes, as a sequela of acute pancreatitis, is observed across the spectrum of severity in acute pancreatitis and can be associated with other clinical complications. The pathophysiology of acute pancreatitis-related diab...
#1Yasuki Hori (Nagoya City University)H-Index: 13
#2Suresh T. Chari (Mayo Clinic)H-Index: 103
Last. Akira Satou (Aichi Medical University)H-Index: 8
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Biliary strictures caused by inflammation or fibrosis lead to jaundice and cholangitis which often make it difficult to distinguish malignant strictures. In cases when malignancy cannot be excluded, surgery is often performed. The concept of immunoglobulin G4 (IgG4)-related sclerosing cholangitis (SC) as a benign biliary stricture was recently proposed. The high prevalence of the disease in Asian countries has resulted in multiple diagnostic and treatment guidelines; however, there is need to fo...
#1Mark O. Goodarzi (NIH: National Institutes of Health)
#2Maxim S. PetrovH-Index: 28
Last. Phil A. HartH-Index: 29
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PURPOSE OF REVIEW The purpose of this review is to delineate risk factors for the development of diabetes in patients with chronic pancreatitis. The natural history including progression to diabetes and complications that develop once diabetes occurs in chronic pancreatitis is also reviewed. RECENT FINDINGS Studies have found that predictors of diabetes in chronic pancreatitis include both risk factors for type 2 diabetes (e.g., obesity, genetic variants) as well as pancreas-specific factors (e....
#1Stephen A. Firkins (The Ohio State University Wexner Medical Center)
#2Phil A. HartH-Index: 29
Last. Somashekar G. KrishnaH-Index: 21
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OBJECTIVES There is a paucity of studies evaluating predictors of new-onset diabetes mellitus (DM) after acute pancreatitis (AP-related DM). We used a population-based database to evaluate predictors of AP-related DM. METHODS The Nationwide Readmissions Database (2010-2014) was used to identify all nondiabetic adults with an index primary diagnosis of AP. Multiple exclusions were applied to identify cohorts with and without AP-related DM. A case-control study was conducted to identify risk facto...
#1Mitchell L. Ramsey (The Ohio State University Wexner Medical Center)H-Index: 4
#2Luis F. LaraH-Index: 22
Last. Darwin L. ConwellH-Index: 53
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OBJECTIVES We hypothesized that hospitalizations in cystic fibrosis (CF) would reflect the development of age-related comorbidities. METHODS A retrospective analysis was performed using the Nationwide Inpatient Sample (2002-2017). Hospitalizations for which the principal diagnosis was CF were analyzed regarding age at discharge and presence of comorbidities. Trends were assessed for significance using the Cochran-Armitage test. RESULTS The mean age of patients hospitalized for CF increased from ...
#1Christopher J. Langmead (CMU: Carnegie Mellon University)H-Index: 21
#2Peter Lee (HUP: Hospital of the University of Pennsylvania)H-Index: 9
Last. Georgios I. Papachristou (University of Pittsburgh)H-Index: 49
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INTRODUCTION Existing laboratory markers and clinical scoring systems have shown suboptimal accuracies for early prediction of persistent organ failure (POF) in acute pancreatitis (AP). We used information theory and machine learning to select the best-performing panel of circulating cytokines for predicting POF early in the disease course and performed verification of the cytokine panel's prognostic accuracy in an independent AP cohort. METHODS The derivation cohort included 60 subjects with AP...