Tarun Singhal
Brigham and Women's Hospital
The InternetInternal medicineRadiologySurgeryPathologyBusinessNeurologyNorepinephrine transporterNew product developmentStandardized uptake valuePositron emission tomographyTranslocator proteinMultiple sclerosisExpanded Disability Status ScaleWhite matterPopulationNuclear medicinePet imagingComputer scienceSupply chain managementKnowledge managementMedicineInternet of Things
68Publications
12H-index
793Citations
Publications 64
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#1Steven Cicero (Brigham and Women's Hospital)H-Index: 1
#2Eero Rissanen (Brigham and Women's Hospital)
Last. Tarun Singhal (Brigham and Women's Hospital)H-Index: 12
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An increasing number of disease-modifying therapies (DMTs) are being approved for treatment of multiple sclerosis …
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#1Tarun SinghalH-Index: 12
#2Eero RissanenH-Index: 15
Last. Howard L. Weiner (Brigham and Women's Hospital)H-Index: 164
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A 64-year-old man with primary progressive multiple sclerosis (Expanded Disability Status Scale 3.5) underwent PET using F-PBR06, a second-generation 18-kDa translocator protein ligand targeting activated brain microglia and astrocytes. Voxel-by-voxel statistical comparison of patient's PET images (acquired 60-90 minutes postinjection) with a healthy control data set was performed to generate a 3-dimensional z-score map of increased radiotracer uptake, which showed widespread increased glial act...
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#1Tarun SinghalH-Index: 12
#2Steven CiceroH-Index: 1
Last. Howard L. WeinerH-Index: 164
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Objective The goal of our study is to assess the role of microglial activation in MS-associated fatigue (MSAF) using [F-18]PBR06-PET. Methods Fatigue severity was measured using the Modified Fatigue Impact Scale (MFIS) in 12 subjects with MS (7 relapsing-remitting and 5 secondary progressive) and 10 healthy control participants who underwent [F-18]PBR06-PET. The MFIS provides a total fatigue score as well as physical, cognitive, and psychosocial fatigue subscale scores. Standardized Uptake Value...
1 CitationsSource
#1Feras Akbik (Emory University)H-Index: 1
#2Matthew Robertson (Brigham and Women's Hospital)H-Index: 4
Last. Henrikas Vaitkevicius (Brigham and Women's Hospital)H-Index: 15
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In the original article, Figure 5 has incorrect EEG images and the corrected version is shown below.
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The research study presents the study of the agile supply chain working as the backbone for an online retail e-commerce system and validates the success factors for an online retail system leading to customer retention. There are some evident reasons for the customers to shop online such as low prices, shopping convenience, easy to compare, free shipping, time-saving, ease of buying and range of products. There needs to be a real-time alignment of both data and physical flow of goods in order to...
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Currently, industry is going through the fourth Industrial Revolution, also termed Industry 4.0. It is characterized mainly by the cyber-physical systems dominated by digital technologies such as the Internet of Things (IoT). Organizations are making significant effort to understand customer needs and subsequently align them to the business goals for achieving market leadership. It is imperative for the longevity of the organization that goods and services be made available to the customer at th...
1 CitationsSource
#1Eleonora Tavazzi (SUNY: State University of New York System)H-Index: 22
#2Robert Zivadinov (SUNY: State University of New York System)H-Index: 83
Last. Niels Bergsland (SUNY: State University of New York System)H-Index: 40
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Introduction: Conventional imaging measures remain a key clinical tool for the diagnosis multiple sclerosis (MS) and monitoring of patients. However, most measures used in the clinic show unsatisfactory performance in predicting disease progression and conversion to secondary progressive MS.Areas covered: Sophisticated imaging techniques have facilitated the identification of imaging biomarkers associated with disease progression, such as global and regional brain volume measures, and with conve...
1 CitationsSource
#1Feras Akbik (Emory University)H-Index: 1
#2Matthew Robertson (Brigham and Women's Hospital)H-Index: 4
Last. Henrikas Vaitkevicius (Brigham and Women's Hospital)H-Index: 15
view all 6 authors...
BACKGROUND: Determining the cause of refractory seizures and/or interictal continuum (IIC) findings in the critically ill patient remains a challenge. These electrographic abnormalities may represent primary ictal pathology or may instead be driven by an underlying infectious, inflammatory, or neoplastic pathology that requires targeted therapy. In these cases, it is unclear whether escalating antiepileptic therapy will be helpful or harmful. Herein, we report the use of serial [F-18] fluorodeox...
1 CitationsSource
One of the defining technological forces which are reshaping world today is the easy accessibility to the Internet. The Internet has changed the way people communicate with each other. Social media whose development was first marshaled by Web 2.0, has revolutionized the entire world of communication. The most intriguing fact is that the world of social media is constantly changing. The platforms which are topping the charts today may not be tomorrow. Also, it can be observed that the power has s...
1 CitationsSource