Carlos López de Silanes
Interquartile rangeInternal medicineLogistic regressionPsychologyRandomized controlled trialCognitionCognitive psychologyEffects of sleep deprivation on cognitive performanceProspective cohort studyAdverse effectImmunologyHazard ratioWorking memoryObservational studyExecutive functionsSerostatusDimethyl fumarateSeroconversionLongitudinal studyTolerabilitySeroprevalenceDiscontinuationJC virusMultiple sclerosisExpanded Disability Status ScaleAtrophyPopulationCognitive disabilitiesAnatomical structuresSerologyPharmacotherapyBrain sizeMedicineCohortVerbal fluency testPhysical medicine and rehabilitation
5Publications
2H-index
24Citations
Publications 5
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#2Julia SabinH-Index: 1
#3Victoria GalanH-Index: 4
Last. Yolanda AladroH-Index: 7
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BACKGROUND Dimethyl fumarate (DMF) has demonstrated efficacy in phase III studies. However, real-world data are still limited. OBJECTIVE The objective of this study was to describe the profile of patients who receive DMF and to assess the effectiveness of DMF regarding relapses, disability progression, magnetic resonance imaging activity, and NEDA (No Evidence Disease Activity)-3 status in a Spanish population in a real-world setting. METHODS We conducted a multicenter prospective study of patie...
1 CitationsSource
#2Ignacio CasanovaH-Index: 8
Last. Carlos López de SilanesH-Index: 2
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BACKGROUND: Dimethyl fumarate (DMF) tolerability and safety in multiple sclerosis (MS) has been analyzed in randomized clinical trials. Real-life studies are needed to assess possible harms of this therapy in a wider MS population. OBJECTIVE: To evaluate DMF tolerability, safety and persistence in MS in a real-world setting. METHODS: We conducted a multicenter prospective study of patients who started DMF, attended in 16 public hospitals of Spain. A specific database was elaborated to collect da...
11 CitationsSource
#1Yolanda Aladro (UEM: European University of Madrid)H-Index: 7
#2Rodrigo Terrero (UEM: European University of Madrid)H-Index: 1
Last. José Meca-Lallana (Universidad Católica San Antonio de Murcia)H-Index: 11
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Abstract Objective To estimate the seroprevalence of anti-JCV antibodies, seroconverting rates and evolution of antibody levels in a multiple sclerosis (MS) Spanish cohort. Methods Multicenter, retrospective cross-sectional and longitudinal study. The JCV seroprevalence was analyzed in 711 MS patients by using 1st (STRATIFY-1) and 2nd generation (STRATIFY-2) two-step ELISA over 2.65 (±0.97) years. Seroconversion rate was obtained over 2 samples from 314 patients, and index stability from 301 pat...
14 CitationsSource