Wei Ren
Chongqing Medical University
Internal medicineEndocrinologyGenotypeOdds ratioInsulin resistanceFatty liverInsulin tolerance testInsulinGrowth hormone deficiencyBody mass indexMetabolic syndromePopulationLipid Accumulation ProductPhysiologyCancer researchBreast cancerDiabetes mellitusAnthropometryMedicineBiology
32Publications
11H-index
381Citations
Publications 35
Newest
#1Wanhua Xu (CQMU: Chongqing Medical University)H-Index: 1
#2Rong Li (CQMU: Chongqing Medical University)H-Index: 8
Last. Qifu Li (CQMU: Chongqing Medical University)H-Index: 20
view all 8 authors...
Inflammatory biomarker high-sensitivity C-reactive protein (hsCRP) is considered as a major predictor of cardiovascular events. Apolipoprotein B (ApoB) directly reflects the number of plasma atherogenic lipoproteins, and may play a major role in vascular inflammation. We aimed to assess whether an association between ApoB and hsCRP exists and, furthermore, to examine whether ApoB is more predictive of the inflammatory status than other cardiovascular risk factors. This was a cross-sectional stud...
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#1Xiao-ya Zheng (CQMU: Chongqing Medical University)H-Index: 4
#2Wei Ren (CQMU: Chongqing Medical University)H-Index: 11
Last. Ping Li (CQMU: Chongqing Medical University)H-Index: 2
view all 10 authors...
TCF7L2 and SLC30A8 have been found to be associated with type 2 diabetes mellitus (T2DM) as well as with impaired proinsulin processing recently, enzymes encoded by PCSK1 and PCSK2 are reported to play an important role in the process of proinsulin conversion. To investigate whether the single nucleotide polymorphisms (SNPs) of TCF7L2, SLC30A8, PCSK1 and PCSK2 were associated with T2DM as well as with proinsulin conversion in a Han Chinese population from Chongqing. A case–control study was perf...
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#1Xiao-ya Zheng (CQMU: Chongqing Medical University)H-Index: 4
#2Wei Ren (CQMU: Chongqing Medical University)H-Index: 11
Last. Ping Li (CQMU: Chongqing Medical University)H-Index: 2
view all 10 authors...
Amylin is the major constituent of pancreatic islet amyloid whose accumulation characterizes patients with type 2 diabetes mellitus (T2DM). Although amylin is tightly linked with T2DM, in many cases, proamylin may be the more toxic species. As the precursor of amylin, however, the pathophysiological role of proamylin remains unknown. In this study, we investigate whether serum levels of proamylin or amylin or the proamylin/amylin ratios are different among normal subjects and patients with impai...
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RT-PCR and immunohistochemistry were used to measure the mRNA and protein expression of insulin receptor substrate 2 (IRS-2) in the muscle of smoking rats. The mRNA and protein expressions of IRS-2 in the smoking subgroups fed with normal diet or high-fat diet were significantly lower than those in corrsponding control groups (0.27±0.02 vs 0.41±0.25, 0.40±0.04 vs 0.51±0.02 for mRNA; 2.91±0.42 vs 4.90±0.29, 2.43±0.36 vs 3.80±0.30 for protein, all P 0.05). The variation of gene expression of IRS-2...
Source
#1Wei Ren (Chongqing University)H-Index: 11
#2Suhua ZhangH-Index: 5
Last. Yin-xing NiH-Index: 1
view all 4 authors...
Background It has been shown that the presence of leptin is associated with deabefes, glucose wefabolism and insulin metablism. In this research, we evaluated the presence of the leptin C - 2 5 4 9 →A polymorphism in the Chinese population in Chongqing and verified its association with plasma leptin levels and anthropometric, metabolic, and clinical parameters. Methods Two hundred and sixty-nine patients with diabetes, 135 non-diabetic first-degree relatives of the patients, and 85 healthy contr...
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