Maykel González-Torres
Monterrey Institute of Technology and Higher Education
Self-healing hydrogelsBiomedical engineeringNanoparticleDermatologyNanotechnologyChemistryExtracellular matrixMaterials scienceScanning electron microscopeGraftingBiocompatibilityCurcuminBiomaterialSwellingPolyurethaneChitosanDrug deliveryDrugXanthan gumFood scienceChemical engineeringPolymerizationTissue engineeringPolymerViability assayPorosityMedicinePharmacology
37Publications
6H-index
153Citations
Publications 37
Newest
Surfactants are essential in the manufacture of polymeric nanoparticles by emulsion formation methods and to preserve the stability of carriers in liquid media. The deposition of non-ionic surfactants at the interface allows a considerable reduction of the globule of the emulsion with high biocompatibility and the possibility of oscillating the final sizes in a wide nanometric range. Therefore, this review presents an analysis of the three principal non-ionic surfactants utilized in the manufact...
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#1María L. Del Prado-Audelo (Tec: Monterrey Institute of Technology and Higher Education)H-Index: 7
#2Isaac H. Caballero-Florán (IPN: Instituto Politécnico Nacional)H-Index: 5
Last. Gerardo Leyva-Gómez (UNAM: National Autonomous University of Mexico)H-Index: 12
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The research of self-healable polymers intended for medical use has increased in the last 20 years. These materials can self-repair and recover their functionality after damage; thus, they are of significant interest in diverse academic areas, including the biomedical field. In this regard, numerous synthetic and natural polymers are being used to develop self-healing hydrogels for tissue engineering applications, particularly for the restoration of bones, cartilage, skin, and even the central n...
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Polyhydroxybutyrate (PHB) scaffolds, produced by electrospinning and coated by plasma polymerization of pyrrole, were used as cell culture substrate for beta cells. PHB is a natural polymer that is biocompatible and bioresorbable. The electrospinning conditions used, produced scaffolds with large surface area and high porosity. The scaffold surface was modified by plasma polymerization of pyrrole doped with iodine (PPyI). The morphology of the scaffolds was characterized by scanning electron mic...
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#2María Luisa Del Prado-Audelo (Tec: Monterrey Institute of Technology and Higher Education)
Last. Gerardo Leyva-GómezH-Index: 12
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Nanoparticles possess a huge potential to be employed in numerous biomedical purposes; their applications may include drug delivery systems, gene therapy, and tissue engineering. However, the in vivo use in biomedical applications requires that nanoparticles exhibit sterility. Thus, diverse sterilization techniques have been developed to remove or destroy microbial contamination. The main sterilization methods include sterile filtration, autoclaving, ionizing radiation, and nonionizing radiation...
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#2Ilian Haide Serrano-Aguilar (UNAM: National Autonomous University of Mexico)
Last. Cristina VelasquilloH-Index: 10
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Abstract A novel brush-like poly(2-aminoethyl methacrylate) (PAEMA) was grafted onto chitosan (CS) through gamma radiation-induced polymerization. The copolymer (CS-g-PAEMA) was used to prepare a sodium acetate leached poly(urethane-urea) scaffold. The above derivatives were developed, synthesized, and characterized to meet the specific characteristics of biomaterials. The results revealed that this method is an easy and successful route for grafting PAEMA onto CS. The feasibility of preparing a...
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Last. José González-Valdez (Tec: Monterrey Institute of Technology and Higher Education)H-Index: 14
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Abstract This work aims to study the bio-interfacial properties of poly(ester-urethane) composite scaffolds based on poly (3-hydroxybutyrate) [PHB] and modified by surface plasma-radiation-induced graft polymerization of N-isopropylacrylamide (NIPAAm). The delivering power of the Argon radio-frequency plasma was increased from 5−20 W. The yields over the polyurethane surface, grafting density, topographical dimensions, architecture, surface energy, and wettability were surveyed in the establishe...
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#1Gabriela Olmos-Olmos (BUAP: Benemérita Universidad Autónoma de Puebla)
#2Bernardo Teutle-Coyotecatl (UAEM: Universidad Autónoma del Estado de México)H-Index: 1
Last. María de los Angeles Moyaho-Bernal (BUAP: Benemérita Universidad Autónoma de Puebla)H-Index: 3
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Reinforced glass ionomer cements have been widely used in pediatric dentistry to prevent dental caries. However, the influence of biomaterial light-curing and its anti-cariogenic effects remain unclear. This study evaluates the influence of the light-curing time on fluoride release, surface topography, and bacterial adhesion in two types of resin-modified glass ionomer cements (RMGICs). One hundred disks were made, and samples were divided into two groups (n = 50 per group), according to each de...
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#1Analizet Villar-Padilla (UNAM: National Autonomous University of Mexico)
#2María L. Del Prado-Audelo (UNAM: National Autonomous University of Mexico)H-Index: 7
Last. Gerardo Leyva-Gómez (UNAM: National Autonomous University of Mexico)H-Index: 12
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Bacterial vaginosis is a vaginal infection that affects 60% of women of reproductive age worldwide. It is mainly caused by the bacterium Gardnerella vaginalis and is a factor that increases the probability of getting sexually transmitted diseases. We aimed to develop a new pharmaceutical form for the treatment of vaginal infections. We employed the solving-casting method to fabricate a polymeric film with Xanthan gum, a natural polymer produced by the bacterium Xanthomonas campestris, and metron...
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#1Fernanda Kamila Godoy-Alvarez (UNAM: National Autonomous University of Mexico)
Last. Gerardo Leyva-Gómez (UNAM: National Autonomous University of Mexico)H-Index: 12
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Hyaluronic acid (HA) is one of the most attractive natural polymers employed in biomaterials with biological applications. This polysaccharide is found in different tissues of the body because it is a natural component of the extracellular matrix; furthermore, it has crucial functions in cell growth, migration, and differentiation. Since its biological characteristics, HA has been utilized for the new biomaterial’s development for tissue engineering, such as hydrogels. These hydrophilic macromol...
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#1Hernán CortésH-Index: 10
#2Octavio D. Reyes-Hernández (UNAM: National Autonomous University of Mexico)H-Index: 6
Last. Gerardo Leyva-Gómez (UNAM: National Autonomous University of Mexico)H-Index: 12
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Parkinson’s disease (PD) is one of the most prevalent neurodegenerative disorders worldwide. It is caused by the degeneration of dopaminergic neurons from the substantia nigra pars compacta. This neuronal loss causes the dopamine deficiency that leads to a series of functional changes within the basal ganglia, producing motor control abnormalities. L-DOPA is considered the gold standard for PD treatment, and it may alleviate its clinical manifestations for some time. However, its prolonged admin...
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