Ying Zhang
Southern Medical University
Self-healing hydrogelsH&E stainInternal medicineEndocrinologyFinite element methodBiomedical engineeringSoft tissueSurgeryArtificial boneStromal cellBone remodelingChemistryMedullary cavityIn vitroScanning electron microscopeHumerusHarris Hip ScoreBone graftingSittingOsteotomyDynamic hip screwExternal fixationBone mineralHalloysiteDextranNanotubePelvisHemostasisBone tissueAnklePubic symphysisSubtalar jointChitosanCubitus varusDeformityCalcaneal fractureAcetabular fractureWound healingSanders classificationFemurHeterotopic ossificationInternal fixationGroup ACoxa varaValgusElbowCortical boneCalcium Sulfate HemihydrateLower anteriorRat Bone MarrowOrthodontics3d simulationNuclear medicineBlood lossComputer aidSignificant differenceDextran sulfate3d printedBone morphogenetic proteinRecombinant DNAChemical engineeringAdhesiveMedicineAcetabulumStainingBone healingAdhesionScaffoldReticular connective tissue
10Publications
1H-index
16Citations
Publications 9
Newest
#1Zhan Li (Southern Medical University)
#2Binglin Li (Southern Medical University)H-Index: 3
Last. Ying Zhang (Southern Medical University)H-Index: 1
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Abstract A series of halloysite nanotube (HNT)-doped chitosan (CS)/oxidized dextran (ODEX) adhesive hydrogels were developed through a Schiff base reaction. The resultant CS/ODEX/HNT hydrogels could not only form in situ on wounds within only 1 s when injected, but could also adapt to wounds of different shapes and depths after injection. We established four rat and rabbit hemorrhage models and demonstrated that the hydrogels are better than the clinically used gelatin sponge for reducing hemost...
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#1Xiangling YeH-Index: 1
#2Lihua LiH-Index: 15
Last. Ying ZhangH-Index: 1
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Abstract We developed the 3D-printed poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/calcium sulfate hemihydrate (PHBV/CaSH) scaffolds by using fused deposition modelling (FDM) technique and then coated the scaffolds with chitosan (CS) acetic acid solution. After drying and neutralization, CS hydrogel was formed on the surface of the scaffolds. The resultant PHBV/CaSH/CS scaffolds could promote the adhesion and proliferation of rat bone marrow stromal cells (rBMSCs) and enhance the osteogenesis of ...
13 CitationsSource
#1Zepeng ChenH-Index: 1
#2Yuanjun XiaH-Index: 1
Last. Ying ZhangH-Index: 1
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Objective To investigate the osteogenic ability of dextran sulfate/recombinant human bone morphogenetic protein-2/chitosan (DS/rhBMP2/CS) nano microspheres combined with coralline hydroxyapatite (CHA) in repair of segmental bone defects. Methods DS/rhBMP2/CS microspheres prepared by ionic crosslinking method were adsorbed into CHA by lyophilization. Seventy-two New Zealand rabbits were randomly divided into 3 equal groups after they had been made into models of bone defect at the right radius. T...
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Objective: To evaluate the osteogenic effect of dextran sulfate/recombinant human bone morphogenetic protein 2/chitosan (DS/rhBMP-2/CS) combined with coralline hydroxyapatite (CHA) in repairing large segmental bone defects by radiographic feature. 方法: 取 57 只 24 周龄雄性新西兰大白兔,制备右桡骨 20 mm 长骨缺损模型。将其中 54 只兔随机分为 3 组( n=18),A、B、C 组分别将 CHA、DS/rhBMP-2/CS/CHA 和 rhBMP-2/CHA 人工骨植入骨缺损区域中;余 3 只兔不植入材料作为空白对照组。术后观察动物大体情况;术后 4、8、12 周取材行 X 线片观察,Micro-CT 扫描及三维重建获取新生骨体积。. Results: The experimental animals recovered we...
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Objective To compare the biomechanical stability of 4 internal fixations in treatment of acetabular fracture of the lower anterior column through finite element analysis. Methods One normal adult male pelvis was subjected to 0. 7mm thin-section CT scanning and 379 CT pictures were obtained. Finite element modeling software was used to establish internal fixation models for acetabular fracture of the lower anterior column, including lag screws(A), anterior column reconstruction plate(B), subcutan...
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UNLABELLED: OBJECTIVE To evaluate the ectopic osteogenesis of recombinant human bone morphogenetic protein 2 (rhBMP-2) loaded chitosan (CS)/dextran sulfate (DS) by micro-CT. METHODS: rhBMP-2/CS/DS microspheres were prepared by the ionic crosslinking and its shape was observed under the scanning electron microscope. The release of rhBMP-2 was determined from resultant microspheres by ELISA assay. Forty-eight Sprague Dawley male rats were randomly divided into 4 groups (n = 12), quadriceps muscle ...
To design and produce a lesser trochanteric reduction fixation system and verify its value and effectiveness.A lesser trochanteric reduction fixation system was designed and produced according to the anatomical features of the lesser trochanteric fractures. Sixty-six patients with intertrochanteric fractures of Evans type III were included between January 2010 and July 2012. Of 66 patients, 32 were treated with dynamic hip screw (DHS) assisted with the lesser trochanteric reduction fixation syst...
Objective Supracondylar closing wedge osteotomy is a standard operation for the management of post-traumatic cubitus varus deformity.There are many fixation methods for the broken ends of bone.However,most of these fixation methods are fraught with various complications.To evaluate the methods and functional results of double volume internal fixation for correction of adult post-traumatic cubitus varus deformity.Methods The clinical data were retrospectively reviewed,from 22 cases of adults post...
1 Citations
OBJECTIVE: To precisely treat complicated calcaneal fracture by 3D simulation through computer aid designed operation. METHODS: From November 2007 to March 2008, 38 patients of calcaneal fracture were treated. There were 29 males and 9 females aged 14-69 years old (average 29.8 years old). According to Sanders classification, there were 4 patients of type I, 14 of type II, 12 of type III, and 8 of type IV. The time between injury and surgery was 3 hours to 5 days. The CT images of calcaneal frac...