Fumihiro Mitsunobu
Okayama University
HistamineInternal medicineEndocrinologySurgeryImmunoglobulin ECardiologyChemistryImmunologyAllergyFEV1/FVC ratioAsthmaBronchial hyperresponsivenessInhalationLungBronchoalveolar lavageIn patientVentilatory functionRadonMedicinePulmonary function testingGastroenterology
278Publications
22H-index
1,524Citations
Publications 283
Newest
#1Takahiro Kataoka (RMIT: RMIT University)H-Index: 16
#2Norie Kanzaki (JAEA: Japan Atomic Energy Agency)H-Index: 4
Last. Fumihiro Mitsunobu (Okayama University)H-Index: 22
view all 11 authors...
Source
#1Takahiro Kataoka (RMIT: RMIT University)H-Index: 16
#2Hina Shuto (RMIT: RMIT University)H-Index: 1
Last. Hiroaki Terato (Okayama University)H-Index: 1
view all 11 authors...
Radon inhalation decreases the level of lipid peroxide (LPO); this is attributed to the activation of antioxidative functions. This activation contributes to the beneficial effects of radon therapy, but there are no studies on the risks of radon therapy, such as DNA damage. We evaluated the effect of radon inhalation on DNA damage caused by oxidative stress and explored the underlying mechanisms. Mice were exposed to radon inhalation at concentrations of 2 or 20 kBq/m3 (for one, three, or 10 day...
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#1Akihiro Sakoda (JAEA: Japan Atomic Energy Agency)H-Index: 8
#2Yuu Ishimori (JAEA: Japan Atomic Energy Agency)H-Index: 13
Last. Kiyonori Yamaoka (RMIT: RMIT University)H-Index: 28
view all 7 authors...
It is held that the skin dose from radon progeny is not negligibly small and that introducing cancer is a possible consequence under normal circumstances as there are a number of uncertainties in terms of related parameters such as activity concentrations in air and water, target cells in skin, skin covering materials, and deposition velocities. An interesting proposal has emerged in that skin exposure to natural radon-rich thermal water as part of balneotherapy can produce an immune response to...
Source
#1Takahiro KataokaH-Index: 16
#2Norie KanzakiH-Index: 4
Last. Kiyonori YamaokaH-Index: 28
view all 11 authors...
Source
#1Takahiro Kataoka (RMIT: RMIT University)H-Index: 16
#2Norie Kanzaki (JAEA: Japan Atomic Energy Agency)H-Index: 4
Last. Kiyonori Yamaoka (RMIT: RMIT University)H-Index: 28
view all 11 authors...
Radon inhalation activates antioxidative functions in mouse organs, thereby contributing to inhibition of oxidative stress-induced damage. However, the specific redox state of each organ after radon inhalation has not been reported. Therefore, in this study, we evaluated the redox state of various organs in mice following radon inhalation at concentrations of 2 or 20 kBq/m3 for 1, 3 or 10 days. Scatter plots were used to evaluate the relationship between antioxidative function and oxidative stre...
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#1Yusuke Kobashi (RMIT: RMIT University)H-Index: 2
#2Takahiro Kataoka (RMIT: RMIT University)H-Index: 16
Last. Kiyonori Yamaoka (RMIT: RMIT University)H-Index: 28
view all 9 authors...
Radon therapy has been traditionally performed globally for oxidative stress-related diseases. Many researchers have studied the beneficial effects of radon exposure in living organisms. However, the effects of thoron, a radioisotope of radon, have not been fully examined. In this study, we aimed to compare the biological effects of radon and thoron inhalation on mouse organs with a focus on oxidative stress. Male BALB/c mice were randomly divided into 15 groups: sham inhalation, radon inhalatio...
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#1Reo Etani (RMIT: RMIT University)H-Index: 5
#2Takahiro Kataoka (RMIT: RMIT University)H-Index: 16
Last. Kiyonori Yamaoka (RMIT: RMIT University)H-Index: 28
view all 9 authors...
: Radon therapy using radon (222Rn) gas is classified into two types of treatment: inhalation of radon gas and drinking water containing radon. Although short- or long-term intake of spa water is effective in increasing gastric mucosal blood flow, and spa water therapy is useful for treating chronic gastritis and gastric ulcer, the underlying mechanisms for and precise effects of radon protection against mucosal injury are unclear. In the present study, we examined the protective effects of hot ...
Source
#1Yuu Ishimori (JAEA: Japan Atomic Energy Agency)H-Index: 13
#2Hiroshi Tanaka (JAEA: Japan Atomic Energy Agency)H-Index: 7
Last. Fumihiro Mitsunobu (Okayama University)H-Index: 22
view all 6 authors...
The purpose of this study is to investigate the biokinetics of inhaled radon, radon activity concentrations in mouse tissues and organs were determined after mice had been exposed to about 1 MBq/m3 of radon in air. Radon activity concentrations in mouse blood and in other tissues and organs were measured with a liquid scintillation counter and with a well-type HP Ge detector, respectively. Radon activity concentration in mouse blood was 0.410 ± 0.016 Bq/g when saturated with 1 MBq/m3 of radon ac...
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