Ye-Qing Zhang
Nanjing University of Chinese Medicine
Matrix (chemical analysis)ChemistryElectrosprayBranPaeoniflorinDysbiosisIleumChinese patent medicinePathogenic bacteriaSulfonateBioactive compoundXanthineSulfur dioxideTriterpeneLinoleic acidFumigationSpleenHypoxanthineResidue (chemistry)Moutan cortexLiu-wei-di-huang wanMedicinal herbsMass spectrometricUplc esi qtof msTandem mass spectrometryFood scienceChromatographySulfurGut floraPharmacology
4Publications
2H-index
12Citations
Publications 4
Newest
#1Ye-Ting Zou (Nanjing University of Chinese Medicine)H-Index: 3
#2Jing Zhou (Nanjing University of Chinese Medicine)H-Index: 8
Last. Song-Lin Li (Nanjing University of Chinese Medicine)H-Index: 26
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Abstract Ethnopharmacological relevance Poria cocos (Schw.) Wolf (Poria) is a well-known traditional medicinal fungus. It has been considered to possess spleen-invigorating (Jianpi) effects in traditional Chinese medicine, and is used clinically to treat spleen deficiency (Pixu) with symptoms of intestinal disorders such as diarrhea, indigestion, mucositis and weight loss. The aim of this study To investigate the protective effects of Poria and its three component fractions (Water-soluble polysa...
2 CitationsSource
#1Ye-Ting Zou (Nanjing University of Chinese Medicine)H-Index: 3
#2Fang Long (Nanjing University of Chinese Medicine)H-Index: 3
Last. Song-Lin Li (Nanjing University of Chinese Medicine)H-Index: 26
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INTRODUCTION: Triterpene acids from the dried sclerotia of Poria cocos (Schw.) Wolf (poria) were recently found to possess anti-cancer activities. Identification of more triterpene acid analogues in poria is worthwhile for high throughput screening in anti-cancer drug discovery. OBJECTIVE: To establish an efficient dereplication strategy for identifying triterpene acid analogues in poria based on ultra-performance liquid chromatography with electrospray ionisation quadrupole time-of-flight tande...
2 CitationsSource
#1Ya-Yun Xu (Nanjing University of Chinese Medicine)H-Index: 3
#2Fang Long (Nanjing University of Chinese Medicine)H-Index: 3
Last. Song-Lin Li (Nanjing University of Chinese Medicine)H-Index: 26
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Abstract In traditional Chinese medicine practice, crude herbs are often subjected to traditional processing (Paozhi in Chinese) for a special medicinal purpose. Bran-frying is one of processing methods for Paeoniae Radix Alba (PRA). Previous studies found that paeoniflorin and paeoniflorin sulfonate, a principle bioactive compound and its sulfur-fumigation induced characteristic sulfur-containing derivative, could be used together with sulfur dioxide residue as chemical markers for the quality ...
5 CitationsSource
#1Xiu-Yang Li (Nanjing University of Chinese Medicine)H-Index: 6
#2Fang Long (Nanjing University of Chinese Medicine)H-Index: 3
Last. Song-Lin Li (Nanjing University of Chinese Medicine)H-Index: 26
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Abstract Sulfur fumigation can induce chemical transformation of bioactive components, consequently the alteration of bioactivities or even toxicities of medicinal herbs. Inspecting Chinese patent medicines (CPM) contained sulfur-fumigated constituent herbs is crucial for ensuring the safety and efficacy of CPM. Paeonifiorin sulfonate is a sulfur-fumigation induced compound of Moutan Cortex (MC), one of the main constituent herbs of a commonly used CPM Liu-Wei-Di-Huang-Wan (LWDHW). Herein, we in...
7 CitationsSource