Yaaziel Melgarejo-Ramírez
Biomedical engineeringPathologyCopolymerAdipose tissueEnzymeChemistryMaterials scienceMesenchymal stem cellGraftingBiocompatibilityPolyurethaneWound healingFibroblastAmnionChemical engineeringPolymerizationTissue engineeringViability assayBiofilmContact anglePorosityMedicineCell biology
15Publications
5H-index
38Citations
Publications 15
Newest
#2Ilian Haide Serrano-Aguilar (UNAM: National Autonomous University of Mexico)
Last. Cristina VelasquilloH-Index: 10
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Abstract A novel brush-like poly(2-aminoethyl methacrylate) (PAEMA) was grafted onto chitosan (CS) through gamma radiation-induced polymerization. The copolymer (CS-g-PAEMA) was used to prepare a sodium acetate leached poly(urethane-urea) scaffold. The above derivatives were developed, synthesized, and characterized to meet the specific characteristics of biomaterials. The results revealed that this method is an easy and successful route for grafting PAEMA onto CS. The feasibility of preparing a...
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Last. José González-Valdez (Tec: Monterrey Institute of Technology and Higher Education)H-Index: 14
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Abstract This work aims to study the bio-interfacial properties of poly(ester-urethane) composite scaffolds based on poly (3-hydroxybutyrate) [PHB] and modified by surface plasma-radiation-induced graft polymerization of N-isopropylacrylamide (NIPAAm). The delivering power of the Argon radio-frequency plasma was increased from 5−20 W. The yields over the polyurethane surface, grafting density, topographical dimensions, architecture, surface energy, and wettability were surveyed in the establishe...
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#1Eric Ivan Ochoa-Segundo (UNAM: National Autonomous University of Mexico)H-Index: 1
Last. Rogelio Rodríguez-Talavera (UNAM: National Autonomous University of Mexico)H-Index: 2
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Abstract This study aimed at investigating the synthesis, characterization, and search for a biotechnological application proposal for poly [(R)-3-hydroxybutyric acid] (PHB) grafted with the n-hydroxyethyl acrylamide (HEAA) monomer. The novel copolymer was prepared by 60Co gamma radiation-induced-graft polymerization. The effect of different solvents in the graft polymerization; the degree of grafting, crystallinity, and hydrophilicity; the morphology and the thermal properties were evaluated. T...
2 CitationsSource
#2Alberto Ramírez-Mata (BUAP: Benemérita Universidad Autónoma de Puebla)H-Index: 5
Last. Cristina VelasquilloH-Index: 10
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Abstract A poly(ester-urethane) nanocomposite based on 1,6-hexamethylene diisocyanate-trimer, poly(3-hydroxybutyrate), and silica nanoparticles was prepared. The porosity model involved the sodium-acetate in situ particulate leaching technique. Also, the diversity of applications (multifunctionality) of these composite scaffolds is currently unknown. Herein, the scaffold surface topography, cell adhesion, viability, and the use of Azospirillum brasilense to produce biofilms were investigated. Th...
1 CitationsSource
#1Valentina Alejandra Segovia-Hernández (IPN: Instituto Politécnico Nacional)H-Index: 1
Last. Rosa María Ribas-Aparicio (IPN: Instituto Politécnico Nacional)H-Index: 10
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Abstract The synthesis of the poly(ester-urethanes) using poly(3-hydroxybutyrate) has gained increasing interest as scaffolds for use in tissue engineering despite their moderate hydrophobicity and biocompatibility. However, it is not yet known if the grafting of poly(N‐hydroxyethyl acrylamide) is suitable to improve the degree of hydrophilicity of the surface. This study aims to tailor the surface of these biopolymers by plasma-induced graft polymerization of N‐hydroxyethyl acrylamide. The synt...
3 CitationsSource
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#1Maykel González-Torres (Tec: Monterrey Institute of Technology and Higher Education)H-Index: 6
#1Maykel González-Torres (Tec: Monterrey Institute of Technology and Higher Education)H-Index: 1
Last. Rogelio Rodríguez-Talavera (UNAM: National Autonomous University of Mexico)H-Index: 2
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Background: The search for innovative anti-tubercular agents has received increasing attention in tuberculosis chemotherapy because Mycobacterium tuberculosis infection has steadily increased over the years. This underlines the necessity for new methods of preparation for polymer-drug adducts to treat this important infectious disease. The use of poly(ethylene glycol)(PEG) is an alternative producing anti-tubercular derivatives. However, it is not yet known whether PEGylated isonicotinylhydrazid...
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#2J. García-LópezH-Index: 3
Last. A. M. Brena-MolinaH-Index: 4
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Abstract In Mexico, burns are considered a public health problem; approximately 93% of all burned patients are treated at public hospitals. For patients undergoing extensive burns, prompt skin coverage avoids potential complications, is life-saving, and is the key for acceptable functional and aesthetic results. Many efforts have been undertaken to find new strategies for the treatment of burns. The aim of this study was to create a human Dermo-Epidermal Skin Substitute (hDE-SS) by combining het...
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#1Mario Alberto Pérez-Díaz (IPN: Instituto Politécnico Nacional)H-Index: 5
#1Mario Alberto Pérez-Díaz (IPN: Instituto Politécnico Nacional)H-Index: 2
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Background Treatment of severe or chronic skin wounds is an important challenge facing medicine and a significant health care burden. Proper wound healing is often affected by bacterial infection; where biofilm formation is one of the main risks and particularly problematic because it confers protection to microorganisms against antibiotics. One avenue to prevent bacterial colonization of wounds is the use of silver nanoparticles (AgNPs); which have proved to be effective against non-multidrug-r...
11 CitationsSource
#2Alejandra Romero-Montero (UNAM: National Autonomous University of Mexico)H-Index: 3
Last. Miquel Gimeno (UNAM: National Autonomous University of Mexico)H-Index: 18
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Abstract The poly(gallic acid), produced by laccase-mediated oxidation of gallic acid in aqueous media (pH 5.5) to attain a novel material with well-defined molecular structure and high water solubility (500 mg/mL at 25 °C), has been investigated to understand its potential biological activities. In this regard, a biomedical approach based on cytoprotective effect on human fibroblast cells exposed to UV-irradiation in the presence of the polymer has been demonstrated. The results also shows that...
5 CitationsSource