Jiu-Zhi Yuan
Shenyang Pharmaceutical University
Circular dichroismPharmacognosyProinflammatory cytokineChemistryHeteronuclear single quantum coherence spectroscopyTwo-dimensional nuclear magnetic resonance spectroscopyTerpenoidIn vivoCaesalpiniaDiterpeneArthritisCytokineLipopolysaccharideRanunculaceaeAnti-inflammatoryDexamethasoneTripterygiumFolk medicineCaesalpinia minaxSemiaquilegia adoxoidesInhibitory effectAnti inflammationStereochemistryPharmacology
Publications 3
#1Ziwei Tong (SPU: Shenyang Pharmaceutical University)H-Index: 1
#2Li Cheng (SPU: Shenyang Pharmaceutical University)H-Index: 2
Last. Zhaohua WuH-Index: 2
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Abstract Ethnopharmacological relevance Seeds of Caesalpinia minax Hance called ‘Ku-Shi-Lian’ (KSL) in China have been used as Zhuang or Dai folk medicines for treatment of common cold, fever, rheumatoid arthritis and dysentery for hundred years. Aim of the study This study aimed to investigate therapeutic efficacy of KSL extract using complete Freund's adjuvant (CFA) induced arthritis in a rat model and the anti-inflammatory activity of cassane diterpenes as the main active material basis of th...
17 CitationsSource
#1Lian LianH-Index: 1
#2Xiao-Bin Li (SPU: Shenyang Pharmaceutical University)H-Index: 1
Last. Huiyuan GaoH-Index: 12
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Molecules with diterpene skeletons often possess valuable medicinal properties. Two new diterpenes 1α,6α,7β-triacetoxy-5α-hydroxy-14β-ethyl-O-vouacapane (1) and 2α-acetoxy-14,15-cyclopimara-7β,16-diol (2) were isolated from the seeds of Caesalpinia minax Hance. Their structures were established on the basis of extensive spectroscopic analyses, including HR-ESI-MS, UV, IR, 1D, and 2D NMR (HSQC, HMBC, NOESY) methods. The stereochemical structure of 1 was confirmed via the circular dichroism spectr...
5 CitationsSource
#1Feng Niu (PKU: Peking University)H-Index: 5
#2Hai-Tao Chang (PKU: Peking University)H-Index: 7
Last. Peng-Fei Tu (PKU: Peking University)H-Index: 54
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Two new ent-kaurane-type diterpenoids, E-semiaquilegin (1) and Z-semiaquilegin (2), together with eight known compounds (3–10) were isolated from the dried roots of Semiaquilegia adoxoides (DC.) Makino. The structures of compounds 1 and 2 were elucidated mainly by 2D NMR techniques including 1H–1H COSY, HSQC, HMBC, NOESY as 16α-hydroxy-ent-kaurane-17,20-di-(3,4-dihydroxy-E-cinnamoyl) ester and its (Z)-isomer.
8 CitationsSource