Heather M. Dann
University of Illinois at Urbana–Champaign
GeneCattle feedingInternal medicineEndocrinologyAnimal scienceNutrientGene expressionRegulation of gene expressionAdipose tissueChemistryMicroarrayIce calvingLactationKetosisDairy cattleGlycogenCarnitineFatty liverTriglyceridePregnancyNEFADry matterNet energyLiver functionBlood serumFood scienceFatty acidBiochemistryMetabolismBeta oxidationBiology
20Publications
13H-index
1,774Citations
Publications 20
Newest
#2Shawn S. DonkinH-Index: 33
Last. Arleen B. RifkindH-Index: 30
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#1N.B. Litherland (UIUC: University of Illinois at Urbana–Champaign)H-Index: 6
#2Heather M. Dann (UIUC: University of Illinois at Urbana–Champaign)H-Index: 13
Last. James K. Drackley (UIUC: University of Illinois at Urbana–Champaign)H-Index: 74
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Abstract We determined the effects of day relative to parturition and prepartum plane of nutrition on hepatic partitioning of palmitate metabolism to CO 2 , acid-soluble products (ASP), and esterified products (EP). Multiparous Holsteins (n=74) were fed different amounts of nutrients during the dry period in a 3 (far-off period diet) × 2 (close-up period diet) factorial arrangement. During the far-off period (d −60 to −25) cows received a low-energy control diet fed ad libitum (100NRC) to meet N...
31 CitationsSource
#1Walter Grünberg (Purdue University)H-Index: 15
#2Rudolf Staufenbiel (FU: Free University of Berlin)H-Index: 12
Last. James K. Drackley (UIUC: University of Illinois at Urbana–Champaign)H-Index: 74
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Abstract Hepatic lipidosis and hypophosphatemia are frequently observed in high-yielding periparturient dairy cows. Objectives of this study were to investigate the association of the liver P content with the degree of liver fat accumulation and serum P concentration and to characterize the change in liver P content throughout the transition period. In a cross-sectional study, liver biopsies obtained from 33 Holstein-Friesian cows 14 d postpartum (p.p.) were assayed for total lipid (TLip), triac...
17 CitationsSource
11 CitationsSource
#1Juan J. Loor (UIUC: University of Illinois at Urbana–Champaign)H-Index: 68
#2Robin E. Everts (UIUC: University of Illinois at Urbana–Champaign)H-Index: 27
Last. Harris A. Lewin (UIUC: University of Illinois at Urbana–Champaign)H-Index: 74
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Dairy cows are highly susceptible after parturition to developing liver lipidosis and ketosis, which are costly diseases to farmers. A bovine microarray platform consisting of 13,257-annotated oligonucleotides was used to study hepatic gene networks underlying nutrition-induced ketosis. On day 5 postpartum, 14 Holstein cows were randomly assigned to ketosis-induction ( n = 7) or control ( n = 7) groups. Cows in the ketosis-induction group were fed at 50% of day 4 intake until they developed sign...
264 CitationsSource
#1N.A. Janovick-Guretzky (UIUC: University of Illinois at Urbana–Champaign)H-Index: 1
#2Heather M. Dann (UIUC: University of Illinois at Urbana–Champaign)H-Index: 13
Last. James K. Drackley (UIUC: University of Illinois at Urbana–Champaign)H-Index: 74
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Abstract Selection of appropriate housekeeping genes (HKG) for normalization of quantitative PCR data for genes of interest is critical for interpretation of results. Ideally, copy number of the chosen HKG mRNA will not vary with experimental treatments or physiological state in the tissue studied, which improves accuracy in detecting changes in genes of interest. Because of the liver's dynamic role in metabolism, physiological state or dietary treatments could alter mRNA expression of commonly ...
113 CitationsSource
3 CitationsSource
#1James K. Drackley (UIUC: University of Illinois at Urbana–Champaign)H-Index: 74
Last. Heather M. DannH-Index: 13
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Interest has surged recently in use of highstraw low-energy diets for dry cows. When implemented correctly, these diets have been successful in decreasing incidences of peripartal health disorders. These diets may work by controlling overall energy intake by cows and thereby prevent metabolic changes similar to those that develop in fat cows. By formulating high-bulk TMR that will limit total energy intake but provide adequate amounts of protein and other nutrients, cows can be allowed to consum...
5 Citations
#2Heather M. DannH-Index: 13
Last. James K. DrackleyH-Index: 74
view all 6 authors...
4 Citations
#1D.B. Carlson (UIUC: University of Illinois at Urbana–Champaign)H-Index: 6
#2N.B. Litherland (UIUC: University of Illinois at Urbana–Champaign)H-Index: 6
Last. James K. Drackley (UIUC: University of Illinois at Urbana–Champaign)H-Index: 74
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Abstract l-Carnitine is required for mitochondrial fatty acid oxidation, but the effects of carnitine supplementation on nutrient metabolism during dry matter intake depression have not been determined in dairy cows. Studies in other species have revealed responses to l-carnitine that may be of specific benefit to dairy cows during the periparturient period. Eight lactating Holstein cows (132±36 d in milk) were used in a replicated 4×4 Latin square experiment with 14-d periods. Treatments were f...
55 CitationsSource