Shoudong Li
University of Texas MD Anderson Cancer Center
Telomerase reverse transcriptaseViral replicationPathologymicroRNAPermissiveMesenchymal stem cellMicrovesiclesIn vivoVirusSystemic administrationGlioblastomaOncolytic adenovirusTemozolomideGliomaHamsterStem cellCancer researchFlow cytometryMedicineOncolytic virusBiologyImmune system
4Publications
1H-index
1Citations
Publications 3
Newest
#1Lynette Phillips (University of Texas MD Anderson Cancer Center)H-Index: 4
#2Shoudong Li (University of Texas MD Anderson Cancer Center)H-Index: 1
Last. Frederick F. Lang (University of Texas MD Anderson Cancer Center)H-Index: 76
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BACKGROUND Oncolytic adenoviruses are promising new treatments against solid tumors, particularly for glioblastoma (GBM), and preclinical models are required to evaluate the mechanisms of efficacy. However, due to the species selectivity of adenovirus, there is currently no single animal model that supports viral replication, tumor oncolysis, and a virus-mediated immune response. To address this gap, we took advantage of the Syrian hamster to develop the first intracranial glioma model that is b...
Source
#1Lynette Phillips (University of Texas MD Anderson Cancer Center)H-Index: 4
#2Shoudong Li (University of Texas MD Anderson Cancer Center)H-Index: 1
Last. Frederick Lang (University of Texas MD Anderson Cancer Center)H-Index: 10
view all 9 authors...
Source
#1Shinji Yamashita (University of Miyazaki)H-Index: 6
#2Tal ShaharH-Index: 19
Last. Frederick F. Lang (University of Texas MD Anderson Cancer Center)H-Index: 76
view all 10 authors...
Glioblastoma is the most malignant type of glioma (World Health Organization grade 4) and has a median survival time of only 14.6 months even after the standard treatment of surgical resection followed by radiotherapy with concomitant and adjuvant temozolomide administration. Although some novel and promising anti-glioma agents have been developed, therapeutic advancement has remained disappointing due to the lack of efficient delivery tools. Here we focused on exosomes derived from mesenchymal ...
1 CitationsSource