Esat Mahmut Ozsahin
University Hospital of Lausanne
Internal medicineRadiologySurgeryOncologyRandomized controlled trialLinear particle acceleratorClinical endpointHazard ratioProstateHead and neck cancerClonidineChemoradiotherapyMucositisConcomitantLymphocyte apoptosisClonidine LauriadBreast FibrosisNuclear medicineRare cancerVolumetric modulated arc therapyIn patientRadiation inducedAnesthesiaRadiation therapyMedicine
Publications 16
#1Jordi GiraltH-Index: 30
#2Yungan Tao (Institut Gustave Roussy)H-Index: 23
Last. René-Jean BensadounH-Index: 28
view all 17 authors...
Abstract Purpose Oral mucositis (OM) is a frequent and painful sequelae of concomitant chemoradiation (CRT) used for the treatment of head and neck cancer (HNC) for which there is no effective intervention. This randomized, placebo-controlled study evaluated the efficacy of a novel, mucoadhesive topical tablet formulation of clonidine in mitigating CRT-induced OM in HNC patients. Patients and Methods Patients with HNC undergoing adjuvant radiotherapy (60-66 Gy; 5 x 1.8-2.2 Gy/wk) with concomitan...
#1D. AzriaH-Index: 19
#2Gilles CrehangeH-Index: 10
Last. Esat Mahmut OzsahinH-Index: 6
view all 19 authors...
#1Bora Tas (Yeni Yüzyıl University)H-Index: 2
#2Ismail Faruk Durmus (Yeni Yüzyıl University)H-Index: 2
Last. Esat Mahmut Ozsahin (CHUV: University Hospital of Lausanne)H-Index: 6
view all 7 authors...
Abstract Purpose To report the feasibility, accuracy, and reliability of volumetric modulated arc therapy (VMAT)-based total-body irradiation (TBI) treatment in patients with acute myeloid leukemia (AML) or acute lymphoblastic leukemia (ALL). Materials and methods From 2015 to 2018, 30 patients with AML or ALL were planned and treated with VMAT-based TBI, which consisted of three isocenters and three overlapping arcs. TBI dose was prescribed to 90% of the planning treatment volume (PTV) receivin...
// Celine Bourgier 1 , Florence Castan 1 , Olivier Riou 1 , Tan-Dat Nguyen 2 , Karine Peignaux 3 , Claire Lemanski 1 , Jean-Leon Lagrange 4 , Youlia Kirova 5 , Eric Lartigau 6 , Yazid Belkacemi 4 , Sofia Rivera 7 , Georges Noel 8 , Sebastien Clippe 9 , Francoise Mornex 10 , Christophe Hennequin 11 , Sophie Gourgou 1 , Muriel Brengues 1 , Pascal Fenoglietto 1 , Esat Mahmut Ozsahin 12 and David Azria 1 1 Institute de Recherche en Cancerologie de Montpellier, Inserm U1194, Universite de Montpellier...
#1Yungan TaoH-Index: 23
#2Jordi GiraltH-Index: 30
Last. Michael HenkeH-Index: 27
view all 14 authors...
#1Berardino De BariH-Index: 18
#2Raphael JumeauH-Index: 7
Last. Esat Mahmut Ozsahin (CHUV: University Hospital of Lausanne)H-Index: 6
view all 11 authors...
Background and purpose Intensity-modulated radiotherapy (IMRT), also using volumetric modulated arc therapy (VMAT) and helical tomotherapy (HT) techniques, has been only recently introduced for treating anal cancer patients. We report efficacy and safety HT, and daily image-guided RT (IGRT) for anal cancer. Materials and methods We retrospectively analyzed efficacy and toxicity of HT with or without chemotherapy for anal cancer patients. Local control (LC) and grade 3 or more toxicity rate (CTC-...
article i nfo Background: Monocentric cohorts suggested that radiation-induced CD8 T-lymphocyte apoptosis (RILA) can predict late toxicity after curative intent radiotherapy (RT). We assessed the role of RILA as a predictor of breast fibrosis (bf+) after adjuvant breast RT in a prospective multicenter trial. Methods: A total of 502 breast-cancer patients (pts) treated by conservative surgery and adjuvant RT were re- cruitedatten centers. RILAwasassessedbeforeRTby flowcytometry.ImpactofRILAonbf+(...
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