Moying Li
Shanghai Jiao Tong University
Circular dichroismSystems biologyMass spectrometryChemistryPeroxisome proliferator-activated receptorDecoctionGlycosideRadixIn vivoMetabolomicsAlkaloidMonoterpeneIridoidBile acidCoreopsisRubiaceaeTriterpeneCharacterization (materials science)AnthraquinonesGlucosidePaederia scandensActive componentsProtein degradationChemical constituentsTandem mass spectrometryElectrospray ionizationChromatographyActive ingredientExtraction (chemistry)Lipid metabolismTraditional medicineSignal transductionStereochemistryMechanism (biology)Pharmacology
5Publications
3H-index
12Citations
Publications 5
Newest
#1Moying Li (SJTU: Shanghai Jiao Tong University)H-Index: 3
#2Yongjian GaoH-Index: 1
Last. Tong WuH-Index: 1
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Abstract Systems biology is an approach that employs modern biological techniques and methods to combine the overall regulation of the body by Chinese herbal formulas with systems analysis at the molecular level. In this study, the underlying immunomodulatory mechanisms of yupingfeng granules (YPFG) were investigated based on the integration of metabolomics and network pharmacology methods. Selected routine peripheral blood indicators, body weight, and organ indices related to immunity were firs...
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#1Moying Li (SJTU: Shanghai Jiao Tong University)H-Index: 3
#2Xinyi YueH-Index: 1
Last. Tong WuH-Index: 1
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Yupingfeng granules (YPFG) were isolated from a traditional Chinese medicine (TCM) formulation composed of three herbs (Astragali Radix, Atractylodis Macrocephalae Rhizoma, and Saposhnikoviae Radix). This formulation is used in TCM to tonify qi, and it can help strengthen exterior and reduce sweating. Nevertheless, the active components of YPFG remain unclear. In this study, the chemical constituents of YPFG were systematically characterized by ultra-performance liquid chromatography coupled wit...
1 CitationsSource
#1Liu Xu (Fudan University)H-Index: 1
#2Moying LiH-Index: 3
Last. Tong WuH-Index: 1
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: The Wen-Jing decoction, a traditional Chinese medicine formula, has been used as a blood-activating and stasis-eliminating drug to treat gynaecological syndromes, such as dysmenorrhea, amenorrhea, and menstrual disorders. However, its pharmacodynamic material basis and mechanism of action have not been thoroughly elucidated to date. The goal of this study was to characterize and identify multiple constituents and metabolites in Wen-Jing decoction. An ultra high performance liquid chromatograph...
4 CitationsSource
#1Xue ZhangH-Index: 3
#2Hai-Feng ZhouH-Index: 3
Last. Tong WuH-Index: 1
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Three new anthraquinones, 1-methyl-2,4-dimethoxy-3-hydroxyanthraquinone (6), 1-methoxy-3-hydroxy-2-ethoxymethylanthraquinone (7), and 2-methyl-3-O-β-D-primeveroside (14), together with 15 known compounds, including seven anthraquinones, one iridoid glucoside, three phenolic compounds, three flavone glucosides, and one flavone, were isolated from Paederia scandens. The isolated compounds were elucidated by extensive spectroscopic methods. To the best of our knowledge, six known anthraquinones (1,...
2 CitationsSource
#1Yan RenjieH-Index: 1
#2Moying LiH-Index: 3
Last. Tong WuH-Index: 1
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AbstractTwo new biflavonone compounds, sikokianin D (1) and sikokianin E (2), were isolated from the capitulum of Coreopsis tinctoria. The structures of these compounds were elucidated by spectroscopic techniques including NMR, HRESIMS and circular dichroism (CD).
4 CitationsSource