Alfred M. Sciuto
PathologyMolecular biologyElectrophoretic mobility shift assayInflammationRespiratory tractSulfur mustardNuclear proteinLung injuryRespiratory systemTranscription factorBiology
Publications 1
#1Michele M. DanneH-Index: 2
#2James A. BlankH-Index: 6
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Abstract : Vesicants, such as sulfur mustard (HD), pose an insidious threat to the respiratory tract. Exposure causes acute lung injury characteristic of an inflammatory response. Nuclear Factor-KAPPA B (NF- square B) is a redox sensitive transcription factor important in regulating genes involved in the inflammation. This study evaluated levels of NF-square B following exposure to HD. Male rats were euthanized at 3, 6, or 24 hr following intravenous HD or isopropanol (IPA controls) exposure. Nu...