R Zeuner
University of Kiel
Internal medicineEndocrinologyAntibodyDermatologyAutoantibodyB-cell activating factorProspective cohort studyImmunologyIn vivoLupus erythematosusSystemic lupus erythematosusArthritisInsulin resistanceRheumatoid arthritisPlasmapheresisAutoimmune diseaseClinical trialMedicineBiologyGastroenterology
Publications 41
#1Josephine LassenH-Index: 1
#2R ZeunerH-Index: 12
Last. Janne GierthmühlenH-Index: 16
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#1Ulf M GeisenH-Index: 1
#1Ulf GeisenH-Index: 3
Last. Bimba F. HoyerH-Index: 23
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Introduction In light of the SARS-CoV-2 pandemic, protecting vulnerable groups has become a high priority. Persons at risk of severe disease, for example, those receiving immunosuppressive therapies for chronic inflammatory cdiseases (CIDs), are prioritised for vaccination. However, data concerning generation of protective antibody titres in immunosuppressed patients are scarce. Additionally, mRNA vaccines represent a new vaccine technology leading to increased insecurity especially in patients ...
50 CitationsSource
#1Konrad Aden (CAU: University of Kiel)H-Index: 16
#2Ateequr Rehman (CAU: University of Kiel)H-Index: 29
Last. Philip Rosenstiel (CAU: University of Kiel)H-Index: 93
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Background & Aims Altered interactions between the mucosal immune system and intestinal microbiota contribute to pathogenesis of inflammatory bowel diseases (IBD). It is not clear how inhibitors of cytokines, such as antagonists of tumor necrosis factor (anti-TNF), affect the intestinal microbiome. We investigated the effects of anti-TNF agents on gut microbe community structure and function in a longitudinal 2-step study of patients with IBD. We correlated our findings with outcomes of treatmen...
74 CitationsSource
#1Sabine M. El-Helou (University of Freiburg)H-Index: 1
#1Sabine M. El-Helou (University of Freiburg)H-Index: 1
Last. Bodo GrimbacherH-Index: 79
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Introduction: The German PID-NET registry was founded in 2009, serving as the first national registry of patients with primary immunodeficiencies (PID) in Germany. It is part of the European Society for Immunodeficiencies (ESID) registry. The primary purpose of the registry is to gather data on the epidemiology, diagnostic delay, diagnosis, and treatment of PIDs. Methods: Clinical and laboratory data was collected from 2,453 patients from 36 German PID centres in an online registry. Data was ana...
23 CitationsSource
2 CitationsSource
#1Dominik M. Schulte (CAU: University of Kiel)H-Index: 20
#2K. Paulsen (CAU: University of Kiel)H-Index: 1
Last. Matthias Laudes (CAU: University of Kiel)H-Index: 27
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Abstract Background and aims Chronic inflammatory diseases (CID) are associated with a profound increase in cardiovascular (CV) risk resulting in reduced life expectancy. However, LDL-cholesterol is reported to be low in CID patients which is referred to as the “LDL paradoxon”. The aim of the present study was to investigate whether LDL-particles in CID exhibit an increased content of the highly atherogenic small-dense LDL subfraction (sdLDL). Methods and results In this prospective, single cent...
11 CitationsSource
#1M JüptnerH-Index: 2
#2Friederike Flachsbart (CAU: University of Kiel)H-Index: 18
Last. Johann O. SchröderH-Index: 8
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ObjectivesLow copy numbers and deletion of complement C4 genes are potent risk factors for systemic lupus erythematosus (SLE). However, it is not known whether this genetic association affects the ...
19 CitationsSource
#1Konrad AdenH-Index: 16
Last. P RosenstielH-Index: 3
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Background Patient reported outcome measures are comprised of either sets of questionnaires or patient global assessment based on visual analogue scale (VAS). These patient-reported outcome measures lack accuracy and/or clinical feasibility when comparing heterogeneous patient groups with different diseases, or when characterizing patients with systemic disease involving different organ systems. Objectives Developing a clinical feasible patient-reported outcome measure based VAS assessment of di...
#1Konrad AdenH-Index: 16
#2Ateequr RehmanH-Index: 29
Last. Philip RosenstielH-Index: 93
view all 9 authors...