Xiaoye Yang
Shandong University
Drug carrierFabricationElectrospinningControlled releaseNanotechnologyNanocarriersMaterials scienceIn vivoBiocompatibilityBiodistributionDrug deliveryDoxorubicinDoxorubicin HydrochlorideDrug releaseNanoscopic scaleTissue engineeringDosage formPharmacology
Publications 2
#1Huiling Cheng (SDU: Shandong University)H-Index: 1
#2Xiaoye Yang (SDU: Shandong University)H-Index: 2
Last. Guangxi Zhai (SDU: Shandong University)H-Index: 1
view all 5 authors...
Abstract Electrospinning, as a nanotechnology, is able to produce polymeric fibers materials with nanoscale structure which are also named electrospun fibers material (EFM). These EFMs can be used in many biomedical applications such as wound dressing, tissue engineering, and medical textile materials. Over the last decades, electrospun nanofibers also have been applied to drug delivery such as orodispersible film, solid dispersion and various controlled release dosage forms due to many properti...
43 CitationsSource
#1Baomei Zhang (SDU: Shandong University)H-Index: 4
#2Xiaoye Yang (SDU: Shandong University)H-Index: 2
Last. Guangxi Zhai (SDU: Shandong University)H-Index: 45
view all 4 authors...
Abstract A novel nanocarrier of heparin (Hep) modified graphene oxide (GO) was fabricated via a linker (adipic dihydrazide) and used as a pH-sensitive drug delivery system for controlling the release of anticancer drug doxorubicin (DOX) for anti-tumor therapy. The finally obtained nanocarrier was GO-ADH-Hep with better stability, blood compatibility and biocompatibility confirmed by the hemolytic test and in vitro cytotoxicity study. Its safety issue was greatly improved via Hep modification. Th...
24 CitationsSource