Mukesh Kumar Meher
Indian Institute of Technology Roorkee
Regenerative medicineSelf-healing hydrogelsSurface modificationTargeted drug deliveryBiodegradable wasteBiocompatible materialFabricationNanomaterialsNuclear chemistryMagnetic resonance imagingTransmission electron microscopyDynamic light scatteringGlycosaminoglycanSolubilityNanoparticleRegeneration (biology)NanotechnologyMinimum inhibitory concentrationEnzymeNanocarriersChemistryParticle sizeRenewable energyMaterials scienceContrast (vision)BiocompatibilityEthylene glycolBiopolymer3D bioprintingDrug deliveryNano-CommercializationCandida glabrataCandida albicansPolyolCoatingPeritoneal dialysis fluidCellular MicroenvironmentGadolinium oxideFungal myceliumMaximum efficiencyPolymer compositesChemical reductionSurface coatingAgricultural wasteOral retinoidContrast enhancementChain lengthAntibacterial agentBone replacementDrug releaseSilver nanoparticleEnvironmental scienceChemical engineeringBioplasticNuclear magnetic resonanceReactive oxygen speciesAntimicrobialTissue engineeringRectificationPolymerZincProtonWaste managementBiofilmThermal stabilityNuclear magnetic resonance spectroscopyMagnetic nanoparticlesMicrobiologyNanocomposite
13Publications
4H-index
47Citations
Publications 13
Newest
#1Mukesh Kumar Meher (IITR: Indian Institute of Technology Roorkee)H-Index: 4
#2Krishna Mohan Poluri (IITR: Indian Institute of Technology Roorkee)H-Index: 15
Abstract Synthesis and characterization of nanoparticles with different morphologies coupled to minimal chemical interventions for sustainable applications is one of the contemporary topics in the field of nanotechnology. In the current study, heparinized silver nanoparticles were synthesized using a chemical reduction method. Different concentrations of heparin were used to investigate its role in the stability and morphological properties of silver nanoparticles. Interestingly, it has been obs...
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#1Payal Gupta (IITR: Indian Institute of Technology Roorkee)H-Index: 4
#2Apoorva Goel (IITR: Indian Institute of Technology Roorkee)H-Index: 2
Last. Krishna Mohan Poluri (IITR: Indian Institute of Technology Roorkee)H-Index: 15
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Abstract Global antimicrobial crisis and advent of drug resistant fungal strains has substantially distressed disease management for clinicians. Biodegradable silver nanoparticles (AgNps) emerge as an excellent alternative remedial option. In the current study, the anti-biofilm activity of microwave irradiated kappa-carrageenan (CRG) capped AgNps against Candida albicans, and Candida glabrata was investigated in terms of their effect on reactive oxygen species (ROS) generation, cellular morpholo...
1 CitationsSource
#1Anamika Chaturvedi (BHU: Banaras Hindu University)H-Index: 1
#2Pranjali Pranjali (BHU: Banaras Hindu University)H-Index: 2
Last. Anupam GuleriaH-Index: 12
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Magnetic nanoparticles (MNPs) have widely demonstrated their applicability in many biomedical applications including magnetic resonance imaging (MRI), hyperthermia, and drug delivery. However, the effectiveness of MNPs can be limited for in vivo applications due to their hydrophobic surfaces leading to nanoparticle agglomeration and thus requires appropriate surface modification to enhance colloidal stability. Glycols are widely used coating material for surface modifications of MNPs to improve ...
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#1Kshitij Joshi (IITR: Indian Institute of Technology Roorkee)H-Index: 1
#2Mukesh Kumar Meher (IITR: Indian Institute of Technology Roorkee)H-Index: 4
Last. Krishna Mohan Poluri (IITR: Indian Institute of Technology Roorkee)H-Index: 15
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Recent advances in the field of biomaterials, and an ever-growing need to curb the alarming rate of pollution levels have led to the utilization of biodegradable waste to fabricate sustainable materials with tunable properties. The current study investigated the growth kinetics and morphology of Pleurotus ostreatus (P. ostreatus) mycelium grown on different agricultural wastes such as wheat bran, sugarcane, sawdust and the mixture of these substrates. Further, it delineated the fabrication proce...
1 CitationsSource
#2Sharanya SarkarH-Index: 3
Last. Krishna Mohan PoluriH-Index: 15
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Abstract Fabrication of cellular microenvironment-responsive nanomaterials has revolutionized the novel drug-delivery system for the last decade. pH-responsive nanosystems are considered to be one of the best choices for smart drug delivery. Synthesis of pH-sensitive nanocomposites requires polymeric materials with specific chemical functionalities, which respond to the pH alteration/redox potential in the cellular microenvironment. These drug-loaded nanomaterials when exposed to a different pH ...
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#1Pranjali PranjaliH-Index: 2
#2Mukesh Kumar Meher (IITR: Indian Institute of Technology Roorkee)H-Index: 4
Last. Anupam GuleriaH-Index: 12
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Owing to the peculiar broad-spectrum antimicrobial activities of zinc oxide nanoparticles (ZnO NPs), we envisaged their use to treat bacterial/mycobacterial/fungal infections during peritoneal dialysis (PD) of end-stage renal failure patients. However, a recent study from our lab showed that ZnO-NPs cannot be employed for the same in their naked form owing to their rapid agglomeration. Also, the naked ZnO-NPs showed strong interaction with organic acids present in the PD fluid (i.e., lactate and...
4 CitationsSource
#1Anupam GuleriaH-Index: 12
#2Pranjali PranjaliH-Index: 2
Last. Dinesh KumarH-Index: 17
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We present the impact of surface modifications on the magnetic resonance imaging (MRI) contrast enhancement abilities of gadolinium oxide nanoparticles. A series of gadolinium oxide nanoparticles surface-coated with polyols of different reductive abilities such as diethylene glycol (DEG), triethylene glycol (TEG), tetraethylene glycol (TeEG), and polyethylene glycol (PEG 200) were synthesized. Particle sizes of synthesized Gd2O3 nanoparticles were found to be in correlation with the chain length...
2 CitationsSource
#1Apoorva Goel (IITR: Indian Institute of Technology Roorkee)H-Index: 2
#2Mukesh Kumar Meher (IITR: Indian Institute of Technology Roorkee)H-Index: 4
Last. Krishna Mohan Poluri (IITR: Indian Institute of Technology Roorkee)H-Index: 15
view all 6 authors...
Abstract Maturation of bacterial biofilms and their resistance to recurrent antimicrobial agents results in convoluted infectious diseases. In the current study, kappa-Carrageenan (κ-Carrageenan/CRG), was used to formulate CRG-silver nanocomposites through a facile microwave green synthesis approach. CRG-Ag nanoparticles of size 50 ± 10 nm were obtained by using CRG as a reducing and stabilizing agent. CRG-Ag nanoparticles were highly effective against both S. aureus and P. aeruginosa mediated b...
21 CitationsSource