George Hamilton
Royal Free Hospital
Endothelial stem cellInternal medicineRadiologyBiomedical engineeringSurgeryCardiologyChemistryMaterials scienceCompliance (physiology)EndotheliumVascular surgeryVascular diseaseAsymptomaticAbdominal aortic aneurysmStenosisBlood vessel prosthesisTissue engineeringMedicineNanocomposite
418Publications
70H-index
10.3kCitations
Publications 412
Newest
#1Gaia Franzetti (UCL: University College London)H-Index: 2
#2Mirko Bonfanti (UCL: University College London)H-Index: 4
Last. Stavroula Balabani (UCL: University College London)H-Index: 24
view all 8 authors...
Peripheral arteriovenous malformations (pAVMs) are congenital lesions characterised by abnormal high-flow, low-resistance vascular connections—the so-called nidus—between arteries and veins. The mainstay treatment typically involves the embolisation of the nidus, however the complexity of pAVMs often leads to uncertain outcomes. This study aims at developing a simple, yet effective computational framework to aid the clinical decision making around the treatment of pAVMs using routinely acquired ...
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#1Helena Smith (Royal Free London NHS Foundation Trust)
#2Chung Sim Lim (NIHR: National Institute for Health Research)H-Index: 1
Last. Jocelyn Brookes (Royal Free London NHS Foundation Trust)H-Index: 1
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Objective null Current data on the nature and rate of major complications for embolo-sclerotherapy (EST) of vascular malformations are scarce. However, even fewer studies focus on vascular malformations specific to the head and neck, which confer an increased specific risk of airway compromise, neurologic and ophthalmologic injury. More understanding is required surrounding the type and incidence of complications to improve treatment planning and informed consent. Therefore, this study aimed to ...
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#1Leeying Giet (Royal Free London NHS Foundation Trust)H-Index: 1
#2Nicholas Evans (Royal Free London NHS Foundation Trust)H-Index: 1
Last. Chung Sim Lim (UCL: University College London)H-Index: 1
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OBJECTIVE Embolo-sclerotherapy (EST) is the mainstay therapy for peripheral vascular malformations that involves the exposure of patients to ionizing radiation. We analyzed the radiation exposure to patients from EST of peripheral vascular malformations during a 5-year period in a single specialist center. METHODS All patients who had undergone EST at a single specialist center for peripheral vascular malformations from January 1, 2013 to January 8, 2018 were identified from a prospectively coll...
1 CitationsSource
#1Calver Pang (UCL: University College London)H-Index: 1
#2Nicholas Evans (Royal Free London NHS Foundation Trust)H-Index: 1
Last. Jocelyn Brookes (Royal Free London NHS Foundation Trust)H-Index: 1
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#1Calver Pang (Royal Free London NHS Foundation Trust)H-Index: 1
#2Nicholas Evans (Royal Free London NHS Foundation Trust)H-Index: 1
Last. Jocelyn Brookes (Royal Free London NHS Foundation Trust)H-Index: 1
view all 9 authors...
OBJECTIVE Recently, studies have shown that sirolimus is clinically efficacious in the treatment of some low-flow vascular malformations (LFVM). This study aimed to assess the efficacy and safety of sirolimus in treating complex head and neck (H&N) LFVM that were challenging and/or refractory to standard treatment. METHODS Each patient had baseline and 6-months assessments consisting of clinical history and examination, quality of life (QoL) questionnaires, laboratory investigations, MRI and med...
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#1Calver Pang (UCL: University College London)H-Index: 1
#2Michael Gibson (Royal Free London NHS Foundation Trust)
Last. Chung Sim Lim (UCL: University College London)H-Index: 1
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ABSTRACT Objective Patients with vascular malformations suffer from chronic debilitating symptoms that have been shown to contribute negatively to their quality of life (QoL) and mental health. Despite this, the current literature evaluating the QoL and mental health of patients with vascular malformations remains scarce. The aim was to evaluate the QoL and mental health of patients with vascular malformations. Methods We prospectively analyzed the validated health-related QoL (HRQoL) questionna...
1 CitationsSource
#1Muhammad Asif Kabeer (University Hospitals of North Midlands NHS Trust)
#2Jennifer Cross (Royal Free Hospital)H-Index: 5
Last. George Hamilton (Royal Free Hospital)H-Index: 70
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Contrast-induced nephropathy (CIN) is common. Risk factors include preexisting renal impairment, diabetes, elderly age, and dehydration. In a single-centre prospective study, we investigated which factors are implicated for CIN in patients with peripheral arterial disease due for angiography. Serum creatinine was measured before, 1, 2, and 7 days post-angiography. We also considered the chronic kidney disease stage of the patients at admission and 48 hours post-contrast. All patients received 50...
1 CitationsSource
#1Chung Sim Lim (NIHR: National Institute for Health Research)H-Index: 1
#2Nicholas Evans (Royal Free London NHS Foundation Trust)H-Index: 1
Last. Jocelyn Brookes (Royal Free London NHS Foundation Trust)H-Index: 1
view all 8 authors...
ObjectiveThe current literature on the major complications of embolo-sclerotherapy of upper and lower extremity vascular malformations is scarce. Evaluating and understanding the rates and types of...
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#2George HamiltonH-Index: 70
#1Stephen J.X. Murphy (Boston Children's Hospital)H-Index: 6
#2Soon Tjin Lim (Boston Children's Hospital)H-Index: 4
Last. Dominick J. H. McCabe (Boston Children's Hospital)H-Index: 21
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Background The relationship between von Willebrand factor antigen (VWF:Ag), VWF propeptide (VWFpp), VWFpp/VWF:Ag ratio, ADAMTS13 activity, and microembolic signal (MES) status in carotid stenosis is unknown. Methods This prospective, multicenter study simultaneously assessed plasma VWF:Ag levels, VWFpp levels and ADAMTS13 activity, and their relationship with MES in asymptomatic versus symptomatic moderate-to-severe (≥50–99%) carotid stenosis patients. One-hour transcranial Doppler ultrasound of...
2 CitationsSource